List of publications

G. Visconti, J. Boccard, M. Feinberg, and S. Rudaz, From fundamentals in calibration to modern methodologies: A tutorial for small molecules quantification in liquid chromatography–mass spectrometry bioanalysis, Analytica chimica acta, 1240, 340711 (2023).
D. Pamies, T. Vujic, D. Schvartz, J. Boccard, C. Repond, C. Nunes, S. Rudaz, J.-Ch. Sanchez, V. González-Ruiz, and M.-G. Zurich , Digoxin Induces Human Astrocyte Reaction In Vitro, Molecular Neurobiology, 60, 84–97 (2023).

B. L. Duivelshof, A. Beck, D. Guillarme, and V. D’Atri, Bispecific antibody characterization by a combination of intact and site-specific/chain-specific LC/MS techniques, Talanta, 236, 122836 (2022).
Th. Dumas, F. Courant, Ch. Almunia, J. Boccard, D. Rosain, G. Duporté , J. Armengaud, H. Fenet, and E. Gomez, An integrated metabolomics and proteogenomics approach reveals molecular alterations following carbamazepine exposure in the male mussel Mytilus galloprovincialis, Chemosphere, 286, 131793 (2022).
S. Ferré, V. Gonzalez-Ruiz, J. Zangari, S. Girel, J.-C. Martinou, R. Sardella, and S. Rudaz, Separation and determination of cysteine enantiomers in plasma after derivatization with 4-fluoro-7-nitrobenzofurazan, Journal of Pharmaceutical and Biomedical Analysis, 209, 114539 (2022).
G. Visconti, E. Olesti, V. Gonzalez-Ruiz, G. Glauser, D. Tonoli, P. Lescuyer, N. Vuilleumier, and S. Rudaz, Internal calibration as an emerging approach for endogenous analyte quantification: Application to steroids, Talanta, 240, 123149 (2022).
F. Marquet, V. D’Atri, D. Guillarme, and G. Borchard, A New Practice to Monitor the Fabrication Process of Fab-Targeting Ligands from Bevacizumab by LC-MS: Preparation and Analytical Characterization , Scientia Pharmaceutica, 90(1), 5 (2022).
N. Nupur, S. Joshi, D. Guillarme, and A. S. Rathore, Analytical Similarity Assessment of Biosimilars: Global Regulatory Landscape, Recent Studies and Major Advancements in Orthogonal Platforms, Frontiers in Bioengineering and Biotechnology, 10, 832059 (2022).
E. Tobolkina, V. González-Ruiz, I. Meister, M. de Figueiredo, D. Guillarme, J. Boccard, and S. Rudaz, Challenges in ESI-MS-based Untargeted Metabolomics, Chimia, 76, 90-100 (2022).
K. Plachká, T. Gazárková, J. Škop, D. Guillarme, F. Svec, and L. Nováková, Fast Optimization of Supercritical Fluid Chromatography–Mass Spectrometry Interfacing Using Prediction Equations, Analytical Chemistry, 94, 4841−4849 (2022).
V. González-Ruiz, A. Cores, M. M. Caja, V. Sridharan, M. Villacampa, M. A. Martin, A. Olives, and J. C. Menéndez , Fluorescence Sensors Based on Hydroxycarbazole for the Determination of Neurodegeneration-Related Halide Anions, Biosensors , 12(3), 175 (2022).
I. A. Haidar Ahmad, G. L. Losacco, V. Shchurik, X. Wang, R. D. Cohen, A. N. Herron, S. Aiken, D. Fiorito, H. Wang, M. Reibarkh, T. Nowak, A. A. Makarov, D. R. Stoll, D. Guillarme, I. Mangion, V. K. Aggarwal, J.-Q. Yu, and E. L. Regalado, Trapping-Enrichment Multi-dimensional Liquid Chromatography with On-Line Deuterated Solvent Exchange for Streamlined Structure Elucidation at the Microgram Scale, Angewandte Chemie International Edition , 61, (2022).
R. Deidda, G. L. Losacco, C. Schelling, E. L. Regalado, J.-L. Veuthey, and D. Guillarme, Sub/supercritical fluid chromatography versus liquid chromatography for peptide analysis, Journal of Chromatography A, 1676, 463282 (2022).
A. Murisier, M. Andrie, S. Fekete, M. Lauber, V. D’Atri, K. Iwan, and D. Guillarme, Direct coupling of size exclusion chromatography and mass spectrometry for the characterization of complexmonoclonal antibody products, Journal of Separation Science, 45, 1997-2007 (2022).
H. Lardeux, A. Goyon, K. Zhang, J. M. Nguyen, M. A. Lauber, D. Guillarme, and V. D’Atri, The impact of low adsorption surfaces for the analysis of DNA and RNA oligonucleotides, Journal of Chromatography A, 1677, 463324 (2022).
Th. Bouvarel, B. L. Duivelshof, J. Camperi, T. Schlothauer, A. Knaupp, C. Stella, and D. Guillarme, Extending the performance of FcRn and FcyRIIIa affinity liquid chromatography for protein biopharmaceuticals , Journal of Chromatography A, 1682 , 463518 (2022).
A. Murisier, V. D’Atri, V. Larraillet, S. Pirner, and D. Guillarme, Boosting the Liquid Chromatography Separation of ComplexBispecific Antibody Products by Using the Multi-Isocratic Elution Mode, Separations, 9, 243 (2022).
D. Guillarme, Th. Bouvarel, F. Rouvière, and S. Heinisch, A simple mathematical treatment for predicting linear solvent strength behavior in gradient elution: Application to biomolecules, Journal of Separation Science, 45, 3276–3285 (2022).
S. Fleury-Souverain, J. Maurin, D. Guillarme, S. Rudaz, and P. Bonnabry, Development and application of a liquid chromatography coupled to mass spectrometry method for the simultaneous determination of 23 antineoplastic drugs at trace levels, Journal of Pharmaceutical and Biomedical Analysis, 221, 115034 (2022).
B. Duivelshof, A. Zöldhegyi, D. Guillarme, M. Lauber, and S. Fekete, Expediting the chromatographic analysis of COVID-19 antibody therapeutics with ultra-short columns, retention modeling and automated method development, Journal of Pharmaceutical and Biomedical Analysis, 221, 115039 (2022).
M. K. Aebischer, H. Gizardin-Fredon, H. Lardeux, D. Kochardt, C. Elger, M. Haindl, R. Ruppert, D. Guillarme and V. D’Atri, Anion-Exchange Chromatography at the Service of Gene Therapy: Baseline Separation of Full/Empty Adeno-Associated Virus Capsids by Screening of Conditions and Step Gradient Elution Mode, International Journal of Molecular Sciences, 23(20), 12332 (2022).
A. Murisier, V. D’Atri, S. Pirner, V. Larraillet, S. Fekete, M. Lauber, and D. Guillarme, Ultra-Fast Middle-Up Reversed Phase Liquid Chromatography Analysis of Complex Bispecific Antibodies Obtained in Less Than One Minute, Pharmaceutics, 14, 2315 (2022).
A. Lathuiliere, R. Vernet, E. Charrier, M. Urwyler, O. Von Rohr, M.-C. Belkouch, V. Saingier, Th. Bouvarel, D. Guillarme, A. Engel, P. Salmon, Th. Laumonier, J. Grogg, and N. Mach, Immortalized human myoblast cell lines for the delivery of therapeutic proteins using encapsulated cell technology, Molecular Therapy: Methods & Clinical Development, 26, 441-458 (2022).
A. C. Manna, S. Leo, S. Girel, V. González-Ruiz, S. Rudaz, P. François, and A. L. Cheung, Teg58, a small regulatory RNA, is involved in regulating argininebiosynthesis and biofilm formation in Staphylococcus aureus, Scientific reports, 12(1), 14963 (2022).
R. C. Barrientos, G. L. Losacco, M. Azizi, H. Wang, A. Nguyet Nguyen, V. Shchurik, A. Singh, D. Richardson, I. Mangion, D. Guillarme, E. L. Regalado, and I. A. Haidar Ahmad, Automated Hydrophobic Interaction Chromatography Screening Combined with In Silico Optimization as a Framework for Nondenaturing Analysis and Purification of Biopharmaceuticals, Analytical Chemistry, 94, 17131−17141 (2022).
M. de Figueiredo, S. Giannoukos, S. Rudaz, R. Zenobi, and J. Boccard, Efficiently handling high-dimensional data from multifactorial designs with unequal group sizes using Rebalanced ASCA (RASCA), Journal of Chemometrics, e3401, 1-15 (2022).
T. Vujic, D. Schvartz, I. Liranço Furlani, I. Meister, V. González-Ruiz, S. Rudaz, and J.-Ch. Sanchez, Oxidative Stress and Extracellular Matrix Remodeling Are Signature Pathways of Extracellular Vesicles Released upon Morphine Exposure on Human Brain Microvascular Endothelial Cells, Cells , 11 (23), 3926 (2022).
N. E. Moskaleva, K. M. Shestakova, A. V. Kukharenko, P. A. Markin, M. V. Kozhevnikova, E. O. Korobkova, A. Brito, S. N. Baskhanova, N. V. Mesonzhnik, Y. N. Belenkov, N. V. Pyatigorskaya, E. Tobolkina, S. Rudaz, and S. A. Appolonova, Target Metabolome Profiling-Based Machine Learning as a Diagnostic Approach for Cardiovascular Diseases in Adults, Metabolites, 12 (12) , 1185 (2022).
J.-M. Roussel, C. Schelling, M. Righezza, and J.-L. Veuthey, Application of prediction intervals to the interpretation of the robustness study of a UHPLC method for the separation of cannabinoids, Journal of Pharmaceutical and Biomedical Analysis, 220, 114977 (2022).
A. F. Harris, J. Lacombe, N. M. Sanchez-Ballester, S. Victor, K. A. J. Curran, A. R. Nordquist, B. Thomas, J. Gu, J.-L. Veuthey, I. Soulairol, and F. Zenhausern, Decellularized Spinach Biomaterials Support Physiologically Relevant Mechanical Cyclic Strain and Prompt a Stretch-Induced Cellular Response, ACS Appl. Bio Mater., 5 , 5682-5692 (2022).
L. Leonardo Saldanha, P.-M. Allard, G. Dilarri, S. Codesido, V. González-Ruiz, E. Ferreira Queiroz, H. Ferreira, and J.-L. Wolfender, Metabolomic- and Molecular Networking-Based Exploration of the Chemical Responses Induced in Citrus sinensis Leaves Inoculated with Xanthomonas citri, Journal of Agricultural and Food Chemistry , 70 (46), 14693-14705 (2022).
V. González-Ruiz, A. Cores, M. M. Caja, V. Sridharan, M. Villacampa, M.A. Martín, A.I. Olives, and J.C. Menéndez, Fluorescence Sensors Based on Hydroxycarbazole for the Determination of Neurodegeneration-Related Halide Anions, Biosensors , 12, 175 (2022).

R. Deidda, C. Schelling, J.-M. Roussel, A. Dispas, Ch. De Bleye, E. Ziemons, Ph. Hubert, and J.-L. Veuthey, The analysis of cannabinoids in cannabis samples by supercritical fluid chromatography and ultra-high-performance liquid chromatography: A comparison study, Analytical Science Advances, 2, 2-14 (2021).
E. Olesti, J. Boccard, G. Visconti, V. Gonzalez-Ruiz, and S. Rudaz, From a single steroid to the steroidome: Trends and analytical challenges, Journal of Steroid Biochemistry and Molecular Biology, 206, 105797 (2021).
S. Codesido, D. Guillarme, and S. Fekete, Algorithms to optimize multi-column chromatographic separations of proteins, Journal of Chromatography A, 1637, 461838 (2021).
B. L. Duivelshof, A. Murisier, J. Camperi, S. Fekete, A. Beck, D. Guillarme, and V. D'Atri, Therapeutic Fc-fusion proteins: Current analytical strategies, Journal of Separation Science, 44, 35–62 (2021).
S. Codesido, M. Hanafi, Y. Gagnebin, V. González-Ruiz, S. Rudaz, and J. Boccard, Network principal component analysis: a versatile tool for the investigation of multigroup and multiblock datasets , Bioinformatics, 1-7, (2021).
S. Fekete, A. Murisier, J. M. Nguyen, M. J. Bolton, J. Belanger, A. Beck, J.-L. Veuthey, K. Wyndham, M. A. Lauber, and D. Guillarme, Use of Ultrashort Columns for Therapeutic Protein Separations, Part 2: Designing the Optimal Column Dimension for Reversed-Phase Liquid Chromatography, Analytical Chemistry, 93, 1285-1293 (2021).
S. Fekete, B. Bobaly, J. M. Nguyen, A. Beck, J.-L. Veuthey, K. Wyndham, M. A. Lauber, and D. Guillarme, Use of Ultrashort Columns for Therapeutic Protein Separations. Part 1: Theoretical Considerations and Proof of Concept, Analytical Chemistry, 93, 1277-1284 (2021).
J. Camperi, A. Goyon, D. Guillarme, K. Zhang, and C. Stella, Multi-dimensional LC-MS: the next generation characterization of antibody-based therapeutics by unified online bottom-up, middle-up and intact approaches, Analyst, 146, 747–769 (2021).
S. Olesik, C. West, D. Guillarme, D. Mangelings, and L. Nováková, Analytical challenges encountered and the potential of supercritical fluid chromatography: A perspective of five experts, Analytical Science Advances, Volume 2 (1-2), 76-80 (2021).
K. Plachka, J. Pezzatti, A. Musenga, R. Nicoli, T. Kuuranne, S. Rudaz, L. Nováková, and D. Guillarme, Ion mobility-high resolution mass spectrometry in anti-doping analysis. Part I: Implementation of a screening method with the assessment of a library of substances prohibited in sports, Analytica Chimica Acta, 1152, 338257 (2021).
S. Fekete, A. Murisier, A. Beck, J. Lawhorn, H. Ritchie, B. Boyes, and D. Guillarme, New wide-pore superficially porous stationary phases with low hydrophobicity applied for the analysis of monoclonal antibodies, Journal of Chromatography A, 1642, 462050 (2021).
S. Fekete, A. Murisier, K. Sandra, and D. Guillarme, Hydrophobic Interaction Chromatography (HIC) for the Characterization of Therapeutic Monoclonal Antibodies and Related Products, Part 1: Theoretical Aspects, LC-GC Europe, 34 (3), (2021).
H. Lardeux, B. L. Duivelshof, O. Colas, A. Beck, D. V. McCalley, D. Guillarme, and V. D’Atri, Alternative mobile phase additives for the characterization of protein biopharmaceuticals in liquid chromatography - Mass spectrometry, Analytica Chimica Acta, 1156, 338347 (2021).
G. L. Losacco, J. Oliviera DaSilva, J. Liu, E. L. Regalado, J.-L. Veuthey, and D. Guillarme, Expanding the range of sub/supercritical fluid chromatography: Advantageous use of methanesulfonic acid in water-rich modifiers for peptide analysis., Journal of Chromatography A, 1642, 462048 (2021).
D. Guillarme, B. Bobably, and J.-L. Veuthey, Free Excel Software for Performing Virtual Liquid Chromatography, LC-GC North America, 39(3), (2021).
O. Moyne, F. Castelli, D.J. Bicout, J. Boccard, B. Camara, B. Cournoyer, E. Faudry, S. Terrier, D. Hannani, S. Huot-Marchand, C. Leger, M. Maurin, T. Dung Ngo, C. Plazy, R.A. Quinn, I. Attree, F. Fenaille, B. Toussaint, and A. Le Gouëllec, Metabotypes of Pseudomonas aeruginosa Correlate with Antibiotic Resistance, Virulence and Clinical Outcome in Cystic Fibrosis Chronic Infections, Metabolites, 11(2), 63 (2021).
E. Olesti, V. González-Ruiz, M. F. Wilks, J. Boccard, and S. Rudaz, Approaches in metabolomics for regulatory toxicology applications , Analyst, 146, 1820-1834 (2021).
G. L. Losacco, J.-L. Veuthey, and D. Guillarme, Metamorphosis of supercritical fluid chromatography: A viable tool for the analysis of polar compounds?, Trends in Analytical Chemis, 141 , 116304 (2021).
J. M. Nguyen, X. Liu, M. DeLoffi, A. Murisier, S. Fekete, D. Guillarme, and M. A. Lauber , Aptamer-based immunoaffinity LC-MS using an ultra-short column for rapid attomole level quantitation of intact mAbs , Journal of Chromatography B, 1173, 122694 (2021).
F. Mueller, G.L. Losacco, R. Nicoli, Guillarme, A. Thomas, and E. Grata, Enantiomeric methadone quantitation on real post-mortem dried matrix spots samples: Comparison of liquid chromatography and supercritical fluid chromatography coupled to mass spectrometry, Journal of Chromatography B, 1177, 122755 (2021).
S. Fekete, A. Murisier, G. L. Losacco, J. Lawhorn, J. M. Godinho, H. Ritchie, B. E. Boyes, and D. Guillarme, Using 1.5 mm internal diameter columns for optimal compatibility with current liquid chromatographic systems, Journal of Chromatography A, 1650, 462258 (2021).
E. Deslignière, A. Ehkirch, B. L. Duivelshof, H. Toftevall, J. Sjögren, D. Guillarme, V. D’Atri, A. Beck, O. Hernandez-Alba, and S. Cianférani, State-of-the-Art Native Mass Spectrometry and Ion Mobility Methods to Monitor Homogeneous Site-Specific Antibody-Drug Conjugates Synthesis, Pharmaceuticals, 14, 498 (2021).
S. Fekete, A. Murisier, M. Lauber and D. Guillarme, Empirical correction of non-linear pH gradients and a tool for application to protein ion exchange chromatography, Journal of Chromatography A, 1651, 462320 (2021).
R. Deidda, F. Coppey, D. Damergi, C. Schelling. L. Coïc, J.-L. Veuthey, P.-Y. Sacré, Ch. De Bleye, Ph. Hubert, P. Esseiva, and E. Ziemons, New perspective for the in-field analysis of cannabis samples using handheld near-infrared spectroscopy: A case study focusing on the determination of ? 9-tetrahydrocannabinol , Journal of Pharmaceutical and Biomedical Analysis, Volume 202, 114150 (2021).
A. Dispas, A. Clarke, A. Grand-Guillaume Perrenoud, L.G. Losacco, J-L. Veuthey, Q. Gros, J. Molineau, A. Noireau, C. West, F. Salafia, M. Zoccali, L. Mondello, A. Guillen, J. Wang, K. Zhang, P. Jochems, G. Schad, K. Nakajima, …P. Hubert, Interlaboratory study of a supercritical fluid chroamtography method for the determination of pharmaceutical impurities: Evaluation of multi-systems reproducibility, Journal of Pharmaceutical and Biomedical Analysis, 203, 114206 (2021).
K. Plachka, J. Pezzatti, A. Musenga, R. Nicoli, T. Kuuranne, S. Rudaz, L. Nováková, and D. Guillarme, Ion mobility-high resolution mass spectrometry in doping control analysis. Part II: Comparison of acquisition modes with and without ion mobility, Analytica Chimica Acta, 1175, 338739 (2021).
J. Camperi, I. Grunert, K. Heinrich, M. Winter, S. Ozipek, S. Hoelterhoff, Th. Weindl, K. Mayr, P. Bulau, M. Meier, M. Mølhøj, M. Leiss, Davy Guillarme, A. Bathke, and C. Stella, Inter-laboratory study to evaluate the performance of automated online characterization of antibody charge variants by multi-dimensional LC-MS/MS, Talanta, 234, 122628 (2021).
A. Murisier, S. Fekete, D. Guillarme, and V. D'Atri, The importance of being metal-free: The critical choice of column hardware for size exclusion chromatography coupled to high resolution mass spectrometry, Analytica Chimica Acta, 1183, 338987 (2021).
A. Murisier, B. Duivelshof, S. Fekete, J. Bourquin, A. Schmudlach, M. A. Lauber, J. M. Nguyen and A. Beck, Towards a simple on-line coupling of ion exchange chromatography and native mass spectrometry for the detailed characterization of monoclonal antibodies, Journal of chromatography, 1655, 462499 (2021).
J. A. Navarro-Huerta, A. Murisier, J. M. Nguyen, M. A. Lauber, A. Beck, D. Guillarme, and S. Fekete, Ultra-short ion-exchange columns for fast charge variants analysis of therapeutic proteins, Journal of Chromatography A, 1657, 462568 (2021).
B. L. Duivelshof, S. Denorme, K. Sandra, X. Liu, A. Beck, M. A. Lauber, D. Guillarme, and V. D’Atri, Quantitative N-Glycan Profiling of Therapeutic Monoclonal Antibodies Performed by Middle-Up Level HILIC-HRMSAnalysis, Pharmaceutics, 13, 1744 (2021).
D. Pamies, C. Sartori, D. Schvartz, V. Gonzalez-Ruiz, L. Pellerin, C. Nunes, D. Tavel, V. Maillard, J. Boccard, S. Rudaz, J.-C. Sanchez, and M.-G. Zurich, Neuroinflammatory Response to TNF-alpha and IL1-beta Cytokines Is Accompanied by an Increase in Glycolysis in Human Astrocytes In Vitro , International Journal of Molecular Sciences, 22 (8), 4065 (2021).
O. Salamin, R. Nicoli, T. Langer, J. Boccard, C. Schweizer Grundisch, C. Xu, S. Rudaz, N. Pitteloud, M. Saugy, and T. Kuuranne, Longitudinal evaluation of multiple biomarkers for the detection of testosterone gel administration in women with normal menstrual cycle, Drug Testing and Analysis, , 1-18 (2021).
O. Salamin, R. Nicoli, C. Xu, J. Boccard, S. Rudaz, M. Saugy, N. Pitteloud, and T. Kuuranne, Steroid profiling by UHPLC-MS/MS in dried blood spots collected from healthy women with and without testosterone gel administration, Journal of Pharmaceutical and Biomedical Analysis, 204, 114280 (2021).
S. Sannicolo, M. Giaj Levra, A. Le Gouellec, C. Aspord, J. Boccard, L. Chaperot, B. Toussaint, D. Moro-Sibilot, D. Hannani, and A.-C. Toffart, Identification of a predictive metabolic signature of response to immune checkpoint inhibitors in non-small cell lung cancer: METABO-ICI clinical study protocol, Respiratory Medicine and Research, 80, 100845 (2021).
J. Boccard, D. Schvartz, S. Codesido, M. Hanafi, Y. Gagnebin, B. Ponte, F. Jourdan, and S. Rudaz, Gaining Insights Into Metabolic Networks Using Chemometrics and Bioinformatics: Chronic Kidney Disease as a Clinical Model, Frontiers in Molecular Biosciences, 8, 682559 (2021).
S. Ferré, N. Drouin, V. Gonzalez-Ruiz, and S. Rudaz, Evaluation of a nanoflow interface based on the triple-tube coaxial sheath-flow sprayer for capillary electrophoresis-mass spectrometry coupling in metabolomics, Journal of Chromatography A, 1641, 461982 (2021).
S. Codesido, N. Drouin, S. Ferré, J. Schappler, S. Rudaz, and V. Gonzalez-Ruiz, New insights into the conversion of electropherograms to the effective electrophoretic mobility scale, Electrophoresis , 42, 1875–1884 (2021).
E. Tobolkina and S. Rudaz, Capillary Electrophoresis Instruments for Medical Applications and Falsified Drug Analysis/Quality Control in Developing Countries, Analytical Chemistry , 93(23), 8107-8115 (2021).
J. Franzen, F. Jermann, P. Ghisletta, S. Rudaz, G. Bondolfi, and N. Toan Tran, Psychological Distress and Well-Being among Students of Health Disciplines: The Importance of Academic Satisfaction , International Journal of Environmental Research and Public Health, 18, 215 (2021).
N. Guichard, J. Boccard, S. Rudaz, P. Bonnabry, and S. Fleury-Souverain, Wipe-sampling procedure optimisation for the determination of 23 antineoplastic drugs used in the hospital pharmacy, European Journal Hospital Pharmacy, 28(2), 94-99 (2021).
J.A. Harrill, M.R. Viant, C.L. Yauk, M. Sachana, T.W. Gant, S.S. Auerbach, R.D. Beger, M. Bouhifd, J. O’Brien, L. Burgoon, F. Caiment, D. Carpi, T. Chen, B.N. Chorley, J. Colbourne, R. Corvi, L. Debrauwer, C. O’Donovan, T. Ebbels, D. Ekman, F. Faulhammer, L. Gribaldo, G. Hilton, S. Jones, A. Kende, T. Lawson, S. Leite, P. Leonards, M. Luijten, A. Martin, L. Moussa, S. Rudaz, O. Schmitz, T. Sobanski, V. Strauss, M. Vaccari, V. Vijay, R. Weber, A. J. Williams, A. Williams, R. S. Thomas, and M. Whelan, Progress Towards an OECD Reporting Framework for Transcriptomics and Metabolomics in Regulatory Toxicology, Regulatory Toxicology and Pharmacology , 125 , 105020 (2021).
A.F. Hernandez Jerez, P. Adriaanse, A. Aldrich, P. Berny, T. Coja, S. Duquesne, A. Focks, M. Marinovich, M. Millet, O. Pelkonen, S. Pieper, A. Tiktak, C. J. Topping, A. Widenfalk, M. Wilks, G. Wolterink, U. Gundert?Remy, J. Louisse, S. Rudaz, E. Testai, A. Lostia, J.?L. Dorne, and J. M. Parra Morte, Scientific Opinion of the Scientific Panel on Plant Protection Products and their Residues (PPR Panel) on testing and interpretation of comparative in vitro metabolism studies, EFSA Journal, 19, 6970 (2021).
S. Fekete, A. Murisier, J. M. Nguyen, M. A. Lauber, and D. Guillarme, Negative gradient slope methods to improve the separation of closely eluting proteins , Journal of Chromatography A, 1635, 461743 (2021).
L. Pellissier, A. Koval, L. Marcourt, E. Ferreira Queiroz, N. Lecoultre, S. Leoni, L. M. Quiros Guerrero, M. Barthélémy, B. L. Duivelshof, D. Guillarme, V. Eparvier, K. Perron, J. Chave, D. Stien, K. Gindro, V. Katanaev, and J.L. Wolfender, Isolation and identification of isocoumarin derivatives with specific inhibitory activity against Wnt pathway and metabolome characterization of Lasiodiplodia venezuelensis , Frontiers in Chemistry, 9, 664489 (2021).
C. Barbas, B. Chamkvetadze, S. Furnaleto, M. Ganzera, J. Haginaka, S. Li, R. Moddel, S. Ozkan, and J-L. Veuthey, Preface, Journal of Pharmaceutical and Biomedical Analysis, 113898, 196 (2021).

J. Lacombe, T. Cretignier, L. Meli, E. M. K. Wijeratne, J.-L. Veuthey, M. Cuendet, A. A. L. Gunatilaka, and F. Zenhausern, Withanolide D Enhances Radiosensitivity of Human Cancer Cells by Inhibiting DNA Damage Non-homologous End Joining Repair Pathway, Frontiers in Oncology, 9, 1468 (2020).
D. V. Mc Calley and D. Guillarme, Evaluation of additives on reversed-phase chromatography of monoclonal antibodies using A 1000? A stationary phase, Journal of Chromatography A, 1610, 460562 (2020).
L. Pucciarini, V. González-Ruiz, J. Zangari, J.-C. Martinou, B. Natalini, R. Sardella, and S. Rudaz, Development and validation of a chiral UHPLC-MS method for the analysis of cysteine enantiomers in biological samples, Journal of Pharmaceutical and Biomedical Analysis, 177, 112841 (2020).
E. Olesti, A. Garcia, R. Rahban, M. F. Rossier, J. Boccard, S. Nef, V. González-Ruiz, and S. Rudaz, Steroid profile analysis by LC-HRMS in human seminal fluid, Journal of Chromatography B, 1136, 121929 (2020).
N. Drouin, T. Kloots, J. Schappler, S. Rudaz, I. Kohler, A. Harms, P. Wilhelmus Lindenburg, and Th. Hankemeier, Electromembrane Extraction of Highly Polar Compounds: Analysis of Cardiovascular Biomarkers in Plasma, Metabolites, 10, 4 (2020).
L. Pucciarini, G. Saluti, R. Galarini, A. Carotti, A. Macchiarulo, S. Rudaz, and R. Sardella, Optimized one-pot derivatization and enantioseparation of cysteine: Application to the study of a dietary supplement, Journal of Pharmaceutical and Biomedical Analysis, 180, 113066 (2020).
Y. Gagnebin, J. Pezzatti, P. Lescuyer, J. Boccard, B. Ponte, and S. Rudaz, Combining the advantages of multilevel and orthogonal partial least squares data analysis for longitudinal metabolomics: Application to kidney transplantation, Analytica Chimica Acta, 1099, 26-38 (2020).
J. Pezzatti, J. Boccard, S. Codesido, Y. Gagnebin, A. Joshi, D. Picard, V. Gonzalez-Ruiz, and S. Rudaz, Implementation of liquid chromatography-high resolution mass spectrometry methods for untargeted metabolomic analyses of biological samples: A tutorial, Analytica Chimica Acta, 1105, 28-44 (2020).
M. Patt, K. R. Beck, T. Di Marco, M.- Ch. Jäger, V. González-Ruiz, J. Boccard, S. Rudaz, R. W. Hartmann, M. Salah, Ch. J. van Koppen, M. Grill, and A. Odermatt, Profiling of anabolic androgenic steroids and selective androgen receptor modulators for interference with adrenal steroidogenesis, Biochemical Pharmacology, 172, 113781 (2020).
J. Camperi, D. Guillarme, M. Lei, and C. Stella, Automated middle-up approach for the characterization of biotherapeutic products by combining on-line hinge-specific digestion with RPLC-HRMS analysis, Journal of Pharmaceutical and Biomedical Analysis, 182, 113130 (2020).
E. Wagner, O. Colas, S. Chenu, A. Goyon, A. Murisier, S. Cianferanic, Y. François, S. Fekete, D. Guillarme, V. D’Atri, and A. Beck, Determination of size variants by CE-SDS for approved therapeutic antibodies: Key implications of subclasses and light chain specificities, Journal of Pharmaceutical and Biomedical Analysis, 184, 113166 (2020).
E. Farsang, D. Guillarme, J.-L. Veuthey, A. Beck, M. Lauber, A. Schmudlach, and S. Fekete, Coupling non-denaturing chromatography to mass spectrometry for the characterization of monoclonal antibodies and related products, Journal of Pharmaceutical and Biomedical Analysis, 185, 113207 (2020).
A. Goyon, L. Dai, T. Chen, B. Wei, F. Yang, N. Andersen, R. Kopf, M. Leiss, M. Mølhøj, D. Guillarme, and C. Stella, From proof of concept to the routine use of an automated and robust multi-dimensional liquid chromatography mass spectrometry workflow applied for the charge variant characterization of therapeutic antibodies, Journal of Chromatography A, 1615, 460740 (2020).
M. Lapteva, M. A. Sallam, A. Goyon, D. Guillarme, J.-L. Veuthey, and Y. N. Kalia, Non-invasive targeted iontophoretic delivery of cetuximab to skin, Expert Opinion on Drug Delivery , 17, 589-602 (2020).
G. L. Losacco, E. Marconetto, R. Nicoli, T. Kuuranne, J. Boccard, S. Rudaz, J. -L Veuthey, and D. Guillarme, Supercritical fluid chromatography–mass spectrometry in routine anti-doping analyses: Estimation of retention time variability under reproducible conditions, Journal of Chromatography A, 1616 , 460780 (2020).
S. Fekete, H. Ritchie, J. Lawhorn, J.-L. Veuthey, and D. Guillarme, Improving selectivity and performing online on-column fractioning in liquid chromatography for the separation of therapeutic biopharmaceutical products, Journal of Chromatography A, 1618, 460901 (2020).
D. Guillarme and C. West, Editorial for the virtual special issue SEP 2019, Journal of Chromatography A, 1619, 460888 (2020).
G. L. Losacco, O. Ismail, J. Pezzatti, V. González-Ruiz, J. Boccard, S. Rudaz, J.-L. Veuthey, D. Guillarme, Applicability of Supercritical fluid chromatography–Mass spectrometry to metabolomics. II–Assessment of a comprehensive library of metabolites and evaluation of biological matrices, Journal of Chromatography A, 1620, 461021 (2020).
J. Camperi, L. Dai, D. Guillarme, and C. Stella, Development of a 3D-LC/MS Workflow for Fast, Automated, and Effective Characterization of Glycosylation Patterns of Biotherapeutic Products, Analytical Chemistry, 92, 4357−4363 (2020).
M. Hernández-Mesa, V. D’Atri, G. Barknowitz, M. Fanuel, J. Pezzatti, N. Dreolin, D. Ropartz, F. Monteau, E. Vigneau, S. Rudaz, S. Stead, H. Rogniaux, D. Guillarme, G. Dervilly, and B. Le Bizec, Interlaboratory and Interplatform Study of Steroids Collision Cross Section by Traveling Wave Ion Mobility Spectrometry, Analytical Chemistry, 92, 5013-5022 (2020).
L. M. Schmidtke, G. Antalick, K. Šuklje, J. W. Blackman, J. Boccard, and A. Deloire, Cultivar, site or harvest date: the gordian knot of wine terroir, Metabolomics, 16, 52 (2020).
M. Fernández-García, F. Rey-Stolle, J. Boccard, V. P. Reddy, A. García, B. M. Cumming, A. J. C. Steyn, S. Rudaz, and C. Barbas, Comprehensive Examination of the Mouse Lung Metabolome Following Mycobacterium tuberculosis Infection Using a Multiplatform Mass Spectrometry Approach, Journal of Proteome Research, 19, 2053-2070 (2020).
S. Fekete and D. Guillarme, Editorial for the Special Issue Titled "Biopharmaceuticals 2020" , Journal of Pharmaceutical and Biomedical Analysis, 183, 113198 (2020).
J. Camperi, L. Dai, D. Guillarme, and C. Stella, Fast and Automated Characterization of Monoclonal Antibody Minor Variants From Cell Cultures by Combined Protein-A and Multidimensional LC/MS Methodologies , Analytical Chemistry, 92, 8506−8513 (2020).
B. L. Duivelshof, E. Deslignière, O. Hernandez-Alba, A. Ehkirch, H. Toftevall, J. Sjögren, S. Cianferani, A. Beck, D. Guillarme, and V. D’Atri, Glycan-Mediated Technology for Obtaining Homogeneous Site-Specific Conjugated Antibody? Drug Conjugates: Synthesis and Analytical Characterization by Using Complementary Middle-up LC/HRMS Analysis, Analytical Chemistry, 92, 8170−8177 (2020).
E. Farsang, K. Horváth, A. Beck, Q. Wang, M. Lauber, D. Guillarme, and S. Fekete, Impact of the column on effluent pH in cation exchange pH gradient chromatography, a practical study, Journal of Chromatography A, 1626 , 461350 (2020).
V. D'Atri, A. Murisier, S. Fekete, J.-L. Veuthey, and D. Guillarme, Current and future trends in reversed-phase liquid chromatography-mass spectrometry of therapeutic proteins, Trends in Analytical Chemistry, 130, 115962 (2020).
G. L. Losacco, S. Fekete, J.-L. Veuthey, and D. Guillarme, Investigating the use of unconventional temperatures in supercritical fluid chromatography, Analytica Chimica Acta, 1134, 84-95 (2020).
A. Goyon, D. McDonald, S. Fekete, D. Guillarme, C. Stella, Development of an innovative salt-mediated pH gradient cation exchange chromatography method for the characterization of therapeutic antibodies, Journal of Chromatography B, 1160, 122379 (2020).
N. Drouin, A. Mielcarek, Ch. Wenz, and S. Rudaz, Evaluation of ion mobility in capillary electrophoresis coupled to mass spectrometry for the identi!cation in metabolomics, Electrophoresis, , 1-8 (2020).
O. Salamin, A. Garcia, V. González-Ruiz, F. Rossi, X. Bigard, J. Déglon, Y. Daali, R. Faiss, M. Saugy, and S. Rudaz, Is pain temporary and glory forever? Detection of tramadolusing dried blood spot in cycling competitions, Drug Testing and Analysis, , 1-9 (2020).
F. Zufferey, N. Donzé, R. Rahban, A. Senn, E. Stettler, S. Rudaz, S. Nef, and M. Rossier, Semen endocannabinoids are correlated to sperm quality in a cohort of 200 young Swiss men, Andrology, 8, 1126–1135 (2020).
N. Drouin, M. van Mever, W. Zhang, E. Tobolkina, S. Ferre, A.-C. Servais, M. J. Gou, L.. Nyssen, M. Fillet, G. S.M. Lageveen-Kammeijer, J. Nouta, A. J. Chetwynd, I. Lynch, J. A. Thorn, J. Meixner, Ch. Loßner, M. Taverna, S. Liu, N. T. Tran, Y. Francois, A. Lechner, R. Nehme, G. Al Hamoui Dit Banni, R. Nasreddine, C. Colas, H. H. Lindner, K. Faserl, Ch. Neusuß, M. Nelke, S. Lammerer, C. Perrin, C. Bich-Muracciole, C. Barbas, A. Lopez Gonzalvez, A. Guttman, M. Szigeti, Ph. Britz-McKibbin, Z. Kroezen, M. Shanmuganathan, P. Nemes, E. P. Portero, T. Hankemeier, S. Codesido, V. Gonzalez-Ruiz, S. Rudaz, and R. Ramautar, Capillary Electrophoresis-Mass Spectrometry at Trial by Metabo-Ring: Effective Electrophoretic Mobility for Reproducible and Robust Compound Annotation, Analytical Chemistry, 92, 14103−14112 (2020).
Th. Dumas, J. Boccard, E. Gomez, H. Fenet, and F. Courant, Multifactorial Analysis of Environmental Metabolomic Data in Ecotoxicology: Wild Marine Mussel Exposed to WWTP Effluent as a Case Study, Metabolites, 10(7), 269 (2020).
J. Massana-Codina, S. Schnee, P.-M. Allard, A. Rutz, J. Boccard, E. Michellod, M. Cléroux, S. Schürch, K. Gindro, and J.-L. Wolfender, Insights on the Structural and Metabolic Resistance of Potato (Solanum tuberosum) Cultivars to Tuber Black Dot (Colletotrichum coccodes), Frontiers in Plant Science, 11, 1-19 (2020).
B. Yanibada, U. Hohenester, M. Pétéra, C. Canlet, S. Durand, F. Jourdan, J. Boccard, C. Martin, M. Eugène, D. P. Morgavi, and H. Boudra, Inhibition of enteric methanogenesis in dairy cows induces changes in plasma metabolome highlighting metabolic shifts and potential markers of emission, Scientific Reports, 10, 15591 (2020).
M. Bergé, J. Pezzatti, V. González-Ruiz, L. Degeorges, S. Rudaz, P. H. Viollier, Bacterial cell cycle control by citrate synthase independent of enzymatic activity, eLife, 9, e52272 (2020).
O. Salamin, F. Ponzetto, J. Boccard, S. Rudaz, M. Saugy, T. Kuuranne, R. Nicoli, Development and validation of an UHPLC-MS/MS method for extended serum steroid profiling in female populations, Bioanalysis , 12, (2020).
J. Camperi, D. Guillarme, and C. Stella, Targeted Bottom-up Characterization of Recombinant Monoclonal Antibodies by Multidimensional LC/MS, Analytical Chemistry, 92, 13420−13426 (2020).
C. Barbas, B. Chankvetadze, S. Furlanetto, M. Ganzera, J. Haginaka, S. Li, R. Moaddel, S. Ozkan, and J.-L. Veuthey, Preface, Journal of Pharmaceutical and Biomedical Analysis, 182, 113162 (2020).
K. Sandra and D. Guillarme, Reshaping The Landscape, LCGC Europe, 33, 5 (2020).
J. Pezzatti, V. González-Ruiz, J. Boccard, D. Guillarme, and S. Rudaz, Evaluation of Different Tandem MS Acquisition Modes to Support Metabolite Annotation in Human Plasma Using Ultra High-Performance Liquid Chromatography High Resolution Mass Spectrometry for Untargeted Metabolomics, Metabolites, 10(11), 464 (2020).
B. van de Velde, D. Guillarme, and I. Kohler, Supercritical fluid chromatography – Mass spectrometry in metabolomics: Past, present, and future perspectives, Journal of Chromatography B, 1161, 122444 (2020).
S. Fekete, A. Murisier, J. M. Nguyen, M. A. Lauber, and D. Guillarme, Negative gradient slope methods to improve the separation of closely eluting proteins, Journal of Chromatography A, 1635, 461743 (2020).
G. L. Losacco, M. Rentsch, K. Plachká, F. Monteau, E. Bichon, B. Le Bizec, L. Nováková, R. Nicoli, T. Kuuranne, J.-L. Veuthey, and D. Guillarme, Ultra-high performance supercritical fluid chromatography coupled to tandem mass spectrometry for antidoping analyses: Assessment of the inter-laboratory reproducibility with urine samples, Analytical Science Advances, 2, 68-75 (2020).
N. Guichard, E. Tobolkina, L. El Morabit, P. Bonnabry, N. Vernaz, and S. Rudaz, Determination of antiretroviral drugs for buyers’ club in Switzerland using capillary electrophoresis methods, Electrophoresis, , 1-11 (2020).
S. Yildiz, J. P. Pereira Bonifacio Lopes, M. Bergé, V. González-Ruiz, D. Baud, J. Kloehn, I. Boal-Carvalho, O. P. Schaeren, M. Schotsaert, L. J. Hathaway, S. Rudaz, P. H. Viollier, S. Hapfelmeier, P. Francois, and M. Schmolke, Respiratory tissue-associated commensal bacteria offer therapeutic potential against pneumococcal colonization, eLife, 9, (2020).
V. Borcic, A. Calmy, S. Hurst, Y. Jackson, F. Negro, A. Perrier, H. Wolff, L. Getaz, A.-C. Bréchet, P. Valladores, S. Rudaz, and N. Vernaz, Buyers' club: an alternative for access to treatment?, Revue medicale suisse , 16, 2228-2231 (2020).
Y. Gagnebin, D. A. Jaques, S. Rudaz, S. de Seigneux, J. Boccard, and B. Ponte, Exploring blood alterations in chronic kidney disease and haemodialysis using metabolomics , Scientific Reports , 10, 19502 (2020).
Th. Dumas, B. Bonnefille, E. Gomez, J. Boccard, N. Ariza Castro, H. Fenet, and F. Courant, Metabolomics approach reveals disruption of metabolic pathways in the marine bivalve Mytilus galloprovincialis exposed to a WWTP effluent extract, Science of the Total Environment, 712, 136551 (2020).
D. Guillarme, and K. Sandra, Editorial for the special issue entitled “Advances in pharmaceutical analysis” , LC-GC Europe, 33 (s10), 5 (2020).

V. D’Atri, S. Fekete, A. Clarke, J.-L. Veuthey, and D. Guillarme, Recent Advances in Chromatography for Pharmaceutical Analysis, Analytical Chemistry, 91, 210-239 (2019).
V. D’Atri, L. Nováková, S. Fekete, D. Stoll, M. Lauber, A. Beck, D. Guillarme, Orthogonal Middle-up Approaches for Characterization of the Glycan Heterogeneity of Etanercept by Hydrophilic Interaction Chromatography Coupled to High-Resolution Mass Spectrometry, Analytical Chemistry, 91, 873-880 (2019).
N. Guichard, S. Fekete, D. Guillarme, P. Bonnabry, S. Fleury-Souverain, Computer-assisted UHPLC–MS method development and optimization for the determination of 24 antineoplastic drugs used in hospital pharmacy, Journal of Pharmaceutical and Biomedical Analysis, 164, 395-401 (2019).
V. D’Atri, R. Pell, A. Clarke, D. Guillarme, S. Fekete, Is hydrophobic interaction chromatography the most suitable technique to characterize site-specific antibody-drug conjugates?, Journal of Chromatography A, 1586, 149-153 (2019).
J. Pezzatti, V. González-Ruiz, S. Codesido, Y. Gagnebin, A. Joshi, D. Guillarme, J. Schappler, D. Picard, J. Boccard, and S. Rudaz , A scoring approach for multi-platform acquisition in metabolomics, Journal of Chromatography A, 1592, 47-54 (2019).
A. Murisier, E. Farsang, K. Horváth, M. Lauber, A. Beck, D. Guillarme, S. Fekete, Tuning selectivity in cation-exchange chromatography applied formonoclonal antibody separations, part 2: Evaluation of recent stationary phases, Journal of Pharmaceutical and Biomedical Analysis, 172, 320-328 (2019).
E. Farsang, A. Murisier, K. Horváth, O. Colas, A. Beck, D. Guillarme, and S. Fekete, Optimization of MS-Compatible Mobile Phases for IEX Separation of Monoclonal Antibodies, LCGC Europe , 32, 28-34 (2019).
E. L. Regalado, I. A. Haidar Ahmad, R. Bennett, V. D’Atri, A. A. Makarov, G. R. Humphrey, I. Mangion, D. Guillarme, The Emergence of Universal Chromatographic Methods in the Research and Development of New Drug Substances , Accounts of Chemical Research, 52, 1990-2002 (2019).
E. Ferreira Queiroz, A. Alfattani, A. Afzan, L. Marcourt, D. Guillarme, J.-L. Wolfender, Utility of dry load injection for an efficient natural products isolationat the semi-preparative chromatographic scale, Journal of Chromatography A, , 85-91 (2019).
B. L. Duivelshof, S. Fekete, D. Guillarme, V. D’Atri, A generic workflow for the characterization of therapeutic monoclonal antibodies—application to daratumumab, Analytical and Bioanalytical Chemistry, 411, 4615-4627 (2019).
A. Beck, V. D’Atri, A. Ehkirch, S. Fekete, O. Hernandez-Alba, R. Gahoual, E. Leize-Wagner, Y. François, D. Guillarme, and S. Cianférani, Cutting-edge multi-level analytical and structural characterization of antibody-drug conjugates: present and future, Expert Review of Proteomics, 16, 337-362 (2019).
A. Murisier, M. Lauber, J. Shiner, D. Guillarme, S. Fekete, Practical considerations on the particle size and permeability of ion-exchange columns applied to biopharmaceutical separations, Journal of Chromatography A, 1604, 460487 (2019).
B. L. Duivelshof, W. Jiskoot, A. Beck, J.-L. Veuthey, D. Guillarme, V. D’Atri, Glycosylation of biosimilars: Recent advances in analytical characterization and clinical implications, Analytica Chimica Acta, 1089, 1-18 (2019).
S. Ferré, V. González-Ruiz, D. Guillarme, S. Rudaz, Analytical strategies for the determination of amino acids: Past, present and future trends, Journal of Chromatography B, 1132, 121819 (2019).
S. Fekete, A. Beck, J.-L Veuthey, and D. Guillarme, Proof of Concept To Achieve Infinite Selectivity for the Chromatographic Separation of Therapeutic Proteins, Analytical Chemistry, 91, 12954-12961 (2019).
Y. Gagnebin, J. Pezzatti, P. Lescuyer, J. Boccard, B. Ponte, S. Rudaz, Toward a better understanding of chronic kidney disease with complementary chromatographic methods hyphenated with mass spectrometry for improved polar metabolome coverage, Journal of Chromatography B, 1116, 9-18 (2019).
J. Pezzatti, M. Bergé, J. Boccard, S. Codesido, Y. Gagnebin, P. H. Viollier, V. González-Ruiz and S. Rudaz, Choosing an Optimal Sample Preparation in Caulobacter crescentus for Untargeted Metabolomics Approaches, Metabolites, 9, 193 (2019).
G. L. Losacco, J.-L Veuthey, D. Guillarme, Supercritical fluid chromatography - Mass spectrometry: Recent evolution and current trends, Trends in Analytical Chemistry, 118, 731-738 (2019).
J. Camperi, A. J. Schick, D. Guillarme, A. T. Wecksler, Utilizing Multidimensional LC–MS for Hydroxyl Radical Footprinting Analysis, LC GC North America, 37s, 36-39 (2019).
A. Goyon, M. Kim, L. Dai, Ch. Cornell, F. Jacobson, D. Guillarme, and C. Stella, Streamlined Characterization of an Antibody? Drug Conjugate by Two-Dimensional and Four-Dimensional Liquid Chromatography/Mass Spectrometry, Analytical Chemistry, 91, 14896−14903 (2019).
S. Codesido, S. Rudaz, D. Guillarme, K. Horváth, S. Fekete, Apparent efficiency of serially coupled columns in gradient elution liquid chromatography: Extension to the combination of any column formats, Journal of Chromatography A, 1588, 159–162 (2019).
A. Beck, D. Guillarme, S. Fleury-Souverain, E. Bodier-Montagutelli, and R. Respaud, Anticorps Monoclonaux Biosimilaires, Med Sci (Paris), 35, 1146 - 1152 (2019).
E. Farsang, A. Murisier, K. Horváth, O. Colas, A. Beck, D. Guillarme, and S. Fekete, Optimization of MS-Compatible Mobile Phases for IEX Separation of Monoclonal Antibodies, LCGC North America, 37 (s6), 34-38 (2019).
D. Guillarme, D. S. Hage, Characterization of charge variants for antibody-based biopharmaceuticals by mass spectrometry, Journal of Chromatography B , 121879, 1134–1135 (2019).
N. Marsousi, S. Rudaz, J. A. Desmeules, and Y. Daali, Liquid Chromatography-Tandem Mass Spectrometry Method for Ticagrelor and its Active Metabolite Determination in Human Plasma: Application to a Pharmacokinetic Study, Current Analytical Chemistry, 15, 1-7 (2019).
N. Drouin, P. Kuban, S. Rudaz, S. Pedersen-Bjergaard, J. Schappler, Electromembrane extraction: Overview of the last decade, Trends in Analytical Chemistry, 113 , 357-363 (2019).
D. Neyroud, A. J. Cheng, Ch. Donnelly, N. Bourdillon, A.-L Gassner, L. Geiser, S. Rudaz, B. Kayser, H. Westerblad, and N. Place, Toxic doses of caffeine are needed to increase skeletal muscle contractility, American Journal of Physiology Cell Physiology, 316, C246-C251 (2019).
V. González-Ruiz, D. Schvartz, J. Sandström, J. Pezzatti, F. Jeannere, D. Tonoli, J. Boccard, F. Monnet-Tschudi, J.-C. Sanchez, and S. Rudaz, An Integrative Multi-Omics Workflow to Address Multifactorial Toxicology Experiments, Metabolites, 9, 79 (2019).
N. Guichard, S. Rudaz, P. Bonnabry, S. Fleury-Souverain, Validation and uncertainty estimation for trace amounts determination of 25 drugs used in hospital chemotherapy compounding units, Journal of Pharmaceutical and Biomedical Analysis, 172, 139 - 148 (2019).
S. Codesido, G. M. Randazzo, F. Lehmann, V. González-Ruiz, A. García, I. Xenarios, R. Liechti, A. Bridge, J. Boccard, and S. Rudaz, DynaStI: A Dynamic Retention Time Database for Steroidomics, Metabolites, 9, 85 (2019).
D. Schvartz, V. González-Ruiz, N. Walter, P. Antinori, F. Jeanneret, D. Tonoli, J. Boccard, M.-G. Zurich, S. Rudaz, F. Monnet-Tschudi, J. Sandström, J.-Ch. Sanchez, Protein pathway analysis to study development-dependent effects of acute and repeated trimethyltin (TMT) treatments in 3D rat brain cell cultures, Toxicology in Vitro, 60, 281–292 (2019).
E. H. A. Diop, E. Ferreira Queiroz, L. Marcourt, S. Kicka, S. Rudaz, T. Diop, T. Soldati, J.-L. Wolfender, Antimycobacterial activity in a single-cell infection assay of ellagitannins from Combretum aculeatum and their bioavailable metabolites, Journal of Ethnopharmacology, 238, 111832 (2019).
F. Ponzetto, J. Boccard, R. Nicoli, T. Kuuranne, M. Saugy & S. Rudaz, Steroidomics for highlighting novel serum biomarkers of testosterone doping, Bioanalysis, 11, 1169–1185 (2019).
S. Codesido, S. Rudaz, J.-L. Veuthey, D. Guillarme, G. Desmet, S. Fekete, Impact of particle size gradients on the apparent efficiency of chromatographic columns, Journal of Chromatography A, 1603, 208-215 (2019).
E. H. A. Diop, J. Jacquat, N. Drouin, E. Ferreira Queiroz, J.-L. Wolfender, T. Diop, J. Schappler, S. Rudaz, Quantitative CE analysis of punicalagin in Combretum aculeatum extracts traditionally used in Senegal for the treatment of tuberculosis, Electrophoresis, 40, 2820–2827 (2019).
E. Farsang, A. Murisier, K. Horváth, A. Beck, R. Kormány, D. Guillarme, and S. Fekete, Tuning selectivity in cation-exchange chromatography applied for monoclonal antibody separations, part 1: Alternative mobile phases and fine tuning of the separation, Journal of Pharmaceutical Biomedical Analysis, 168, 138-147 (2019).
V. D'Atri and V. Gabelica, DNA and RNA Telomeric G-Quadruplexes: what Topology Features can be Inferred from Ion Mobility Mass Spectrometry? , Analyst , 144, 6074-6088 (2019).
N. C. Aquino, E. F. Queiroz, L. Marcourt, L. B. N. Freitas, E. V. O. Araújo, L. K. A. M. Leal, A. M. E. Bezerra, J. Boccard, J. -L. Wolfender, and E. R. Silveira, Chemical Composition and Anti-Inflammatory Activity of the Decoction from Leaves of a Cultivated Specimen of Myracrodruon urundeuva, Journal of the Brazilian Chemical Society, 30, 1616-1623 (2019).
J. Boccard, D. Tonoli, P. Strajhar, F. Jeanneret, A. Odermatt, and S. Rudaz,, Removal of batch effects using stratified subsampling of metabolomic data for in vitro endocrine disruptors screening, Talanta, 195, 77–86 (2019).
N. Guichard, J. Boccard, S. Rudaz, P. Bonnabry, and S. Fleury Souverain, Wipe-sampling procedure optimisation for the determination of 23 antineoplastic drugs used in the hospital pharmacy, European Journal of Hospital Pharmacy, Science and Practice, 1-6 (2019).
C. Palaric, S. Pilard, J.?X. Fontaine, J. Boccard, D. Mathiron, S. Rigaud, D. Cailleu, F. Mesnard, Y. Gut, T. Renaud, A. Petit, J.?Y. Beaumal, and R. Molinié, Processing of NMR and MS metabolomics data using chemometrics methods: a global tool for fungi biotransformation reactions monitoring, Metabolomics, 15, (2019).
J. Sandström, D. V. Kratschmar, A. Broyer, O. Poirot, Ph. Marbet, B. Chantong, F. Zufferey, T. Dos Santos, J. Boccard, R. Chrast, A. Odermatt, F. Monnet?Tschudi, In vitro models to study insulin and glucocorticoids modulation of trimethyltin (TMT)-induced neuroinflammation and neurodegeneration, and in vivo validation in db/db mice, Archives of Toxicology, 93, 1649–1664 (2019).
E. Farsang, S. Fekete, and K. Horvath, Tömegspetrométer-barát mozgófázis alkalmazása terápiás fehérjék ioncserés elválasztásához, Kromatográfus, 6, 24-27 (2019).
S. Fekete , A fehérje-kromatográfia alapvet? problémái, Kromatográfus, 6, 18 - 21 (2019).
R. Kormany and S. Fekete, Az ultranagy-hatékonyságú folyadékkromatográfia határai, Magyar Kemiai Folyoirat, 125, 134-142 (2019).

A. Goyon, S. Fekete, A. Beck, J.-L. Veuthey, D. Guillarme, Unraveling the mysteries of modern size exclusion chromatography – the way to achieve confident characterization of therapeutic proteins, Journal of Chromatography B, 1092, 368-378 (2018).
V. Desfontaine, G.L. Losacco, Y. Gagnebin, J. Pezzatti, W.P. Farrell, V. González-Ruiz, S. Rudaz, J.-L. Veuthey, D. Guillarme, Applicability of supercritical fluid chromatography – mass spectrometry to metabolomics. I – Optimization of separationconditions for the simultaneous analysis of hydrophilic and lipophilic substances, Journal of Chromatography A, 1562, 96–107 (2018).
B. Bobaly, J.-L. Veuthey, D. Guillarme, S. Fekete, New development and possibilities of wide-pore superficially porous particle technology applied for the liquid chromatographic analysis of therapeutic proteins, Journal of Pharmaceutical and Biomedical Analysis, 158, 225-235 (2018).
S. Fekete, V. Sadat-Noorbakhsh, C. Schelling, I. Molnat, D. Guillarme, S. Rudaz, J.-L. Veuthey, Implementation of a generic liquid chromatographic method development workflow: Application to the analysis of phytocannabinoids and Cannabis sativa extracts, Journal of Pharmaceutical and Biomedical Analysis, 155, 116-124 (2018).
S. Fekete, A. Goyon, J.-L. Veuthey, and D. Guillarme, Size Exclusion Chromatography of Protein Biopharmaceuticals: Past, Present and Future, American Pharmaceutical Review, 21, 84-87 (2018).
D. Guillarme, V. Desfontaine, S. Heinisch, J.-L. Veuthey, What are the current solutions for interfacing supercritical fluid chromatography and mass spectrometry ?, Journal of Chromatography B, 1083, 160-170 (2018).
O. Ciclet, D. Barron, S. Bajic, J.-L. Veuthey, D. Guillarme, A. Grand-Guillaume-Perrenoud, Natural compounds analysis using liquid and supercritical fluid chromatography hyphenated to mass spectrometry: Evaluation of a new design of atmospheric pressure ionization source, Joural of Chromatography B, 1083, 1-11 (2018).
V. Desfontaine, F. Capetti, R. Nicoli, T. Kuuranne, J.-L. Veuthey, D. Guillarme, Systematic evaluation of matrix effects in supercritical fluid chromatography versus liquid chromatography coupled to mass spectrometry for biological samples, Journal of Chromatography B, 1079, 51-61 (2018).
V. Desfontaine, A. Goyon, J.-L. Veuthey, J. Charve, D. Guillarme, Development of a LC-MS/MS method for the determination of isomeric glutamyl peptides in food ingredients, Journal of Separation Science, , (2018).
V. D'Atri, T. Causon. O. Hernandez-Alba, A. Mutabazi, J.-L. Veuthey, S. Cianferani, D. Guillarme, Adding a new separation dimention to MS and LC-MS: What is the utility of ion mobility spectrometry ?, Journal of Separation Science, 41, 20-67 (2018).
B. Bobaly, S. Fleury-Souverain, A. Beck, J.-L. Veuthey, D. Guillarme, S. Fekete, Current possibilities of liquid chromatography for the caracterization of antibody-drug conjugates, Journal of Pharmaceutical and Biomedical Analysis, 147, 493-505 (2018).
Y. Gagnebin, J. Boccard, B. Ponte, S. Rudaz, Metabolomics in chronic kidney disease: Strategies for extended metabolome coverage, Journal of Pharmaceutical and Biomedical Analysis, 161, 313-325 (2018).
S. Fekete, S. Codesido, S. Rudaz, D. Guillarme, K. Horváth, Apparent efficiency of serially coupled columns in isocratic and gradient elution modes, Journal of Chromatography A, 1571, 121-131 (2018).
N. Drouin, S. Rudaz, J. Schappler, New supported liquid membrane for electromembrane extraction ofpolar basic endogenous metabolites, Journal of Pharmaceutical and Biomedical Analysis, 159, 53-59 (2018).
N. Marsousi, Y. Daali, P. Fontana, J.-L. Reny, V. Ancrenaz-Sirot, A. Calmy, S. Rudaz, J. A. Desmeules. C. F. Samer, Impact of Boosted Antiretroviral Therapy on the Pharmacokinetics and Efficacy of Clopidogrel and Prasugrel Active Metabolites, Clinical Pharmacokinetics , 57, 1347-1354 (2018).
G. Jaffuel, L. Chappuis, D. Guillarme, T. C. J. Turlings, G. Glauser, Improved separation by at-column dilution in préparative hydrophilic interaction chromatography, Journal of Chromatography A, 1532, 136-143 (2018).
S. Fekete, D. Guillarme, Influence of connection tubing in modern size exclusion chromatography and its impact on the caracterization of mAbs, Journal of Pharmaceutical and Biomedical Analysis, 149, 22-32 (2018).
J. Giorgetti, V. D'Atri, J. Canonge, A. Lechner, D. Guillarme, O. Colas, E. Wagner-Rousset, A. Beck, E. Leize-Wagner, Y.-N. François, Monoclonal antibody N-glycosylation profiling using capilarry electrophoresis - Mass spectrometry: Assessment and method validation, Talanta, 178, 530-537 (2018).
N. Marsousi, J,A, Desmeules, S. Rudaz, Y. Daali, Prediction of drug-drug interactions using physiologically-based pharmacokinetic models of CYP450 modulators included inSimcyp software, Biopharm Drug Disposition, 39, 3-17 (2018).
N. Drouin, S. Rudaz, J. Schappler, Sample preparation for polar metabolites in bioanalysis, Analyst, 143, 16-20 (2018).
A. Ehkirch, V. D'Atri, F. Rouvière, O. Hernandez-Alba, A. Goyon, O. Colas, M. Sarrut, A. Beck, D. Guillarme, S. Heinisch, S. Cianferani, An Online Four-Dimensional HIC×SEC-IM×MS Methodology for Proof-of-Concept Characterization of Antibody Drug Conjugates, Analytical Chemistry, 90, 1578-1586 (2018).
A. Goyon, L. Sciascera, A. Clarke, D. Guillarme, R. Pell, Extending the limits of size exclusion chromatography: Simultaneousseparation of free payloads and related species from antibody drugconjugates and their aggregates, Journal of Chromatography A, 1539, 19-29 (2018).
V. D'Atri, S. Fekete, D. Stoll, M. Lauber, A. Beck, D. Guillarme, Characterization of an antibody-drug conjugate by hydrophilic interaction chromatography coupled to mass spectrometry, Journal of Chromatography B, 1080, 37-41 (2018).
B. Bobaly, M. Lauber, A. Beck, D. Guillarme, S. Fekete, Utility of a high coverage phenyl-bonding and wide-pore superficially porous particle for the analysis of monoclonal antibodies and related product, Journal of Chromatography A, 1549, 63-76 (2018).
A. Ehkirch, O. Hernandez-Alba, O. Ciclet, A. Beck, D. Guillarme, S. Cianférani, Hyphenation of size exclusion chromatography to native ion mobility mass spectrometry for the analytical characterization of therapeutic antibodies and related products, Journal of Chromatography B, 1086, 176-183 (2018).
N. Guinchard, M. Ogereau, L. Falaschi, S. Rudaz, P. Bonnabry, S. Souverain, Determination of 16 antineoplastic drugs by capillary electrophoresis with UV detection: Applications in quality control, Electrophoresis, , 1-9 (2018).
ElHadji A. Diop, E. Ferreira Queiroz, S. Kicka, S. Rudaz, T. Diop, T. Soldati, J.-L. Wolfender, Survey on medicinal plants traditionally used in Senegal for the treatment of tuberculosis (TB) and assessment of their antimycobacterial activity, Journal of Ethnopharmacology, 216, 71-78 (2018).
P. Strajhar, D. Tonoli, F. Jeanneret, R. M. Imhof, V. Malagnino, M. Patt, D. V. Kratschmar, J. Boccard, S. Rudaz, A. Odermatt, Steroid profiling in H295R cells to identify chemicals potentially disrupting the production of adrenal steroids, Toxicology, 381, 51-63 (2018).
D.R. Stoll, D.C. Harmes, G.O. Staples, O.G. Potter, C.T. Dammann, D. Guillarme, A. Beck, Development of Comprehensive Online Two-Dimensional Liquid Chromatography/Mass Spectrometry Using Hydrophilic Interaction and Reversed-Phase Separations for Rapid and Deep Profiling of Therapeutic Antibodies, Analytical Chemistry, 90, 5923-5929 (2018).
S. Fekete, D. Guillarme, D. R. Stoll, Tips, Tricks, and Troubleshooting for Separations of Biomolecules, Part 1: Contemporary Reversed-Phase Protein Separations, LC/GC Europe, 37/8, 427-431 (2018).
S. Fekete, D. Guillarme, D. R. Stoll, LC TROUBLESHOOTING Tips, Tricks, and Troubleshooting for Separations of Biomolecules, Part I: Contemporary Reversed-Phase Protein Separations , LC/GC North America, 36/7, 440/446 (2018).
B. Bobály, V. D'Atri, M. Lauber, A. Beck, D. Guillarme, S. Fekete, Characterizing various monoclonal antibodies with milder reversed phase chromatography conditions, Journal of Chromatography B , 1096, 1-10 (2018).
A. Goyon, Y. N. Francois, O. Colas, A. Beck, J.-L Veuthey, D. Guillarme, High-resolution separation of monoclonal antibodies mixtures and their charge variants by an alternative and generic CZE method, Electrophoresis, 39, 2083-2090 (2018).
V. D'Atri, A. Goyon, B. Bobalya, A. Beck, S. Fekete, D. Guillarme,, Protocols for the analytical characterization of therapeutic monoclonal antibodies. III – Denaturing chromatographic techniques hyphenated to mass spectrometry, Journal of Chromatography B, 1096, 95-106 (2018).
J. Camperi, A. Combes, J. Guibourdenche, D. Guillarme, V. Pichon, T. Fournier, N. Delaunay, An attempt to characterize the human Chorionic Gonadotropinprotein by reversed phase liquid chromatography coupled withhigh-resolution mass spectrometry at the intact level, Journal of Pharmaceutical and Biomedical Analysis, 161, 35-44 (2018).
D. Guillarme, J.-L Veuthey, Supercritical fluid chromatography – mass spectrometry, Journal of Chromatography B, 1095, 275 (2018).
A. Dispasa, R. Marini, V. Desfontaine, J.-L Veuthey, D. Kotoni, L. G. Losacco, A. Clarke, C. Muscat Galea, D. Mangelings, B. M. Jocher, E. L. Regalado, K. Plachká, L. Nováková, B. Wuyts, I. Francois, M. Gray, A. J. Aubin, Abhijit Tarafder, M. Cazes, Ch. Desvignes, L. Villemet, M. Sarrut, A. Raimbault, E. Lemasson, E. Lesellier, C. West, T. Leek, M. Wong, L. Dai, K. Zhang, A. Grand-Guillaume Perrenoud, C. Brunelli, Ph. Hennig, S. Bertin, F. Mauge, N. Da Costa, W. P. Farrell, M. Hills, N. Desphande, M. Grangrade, S. Sadaphule, R. Yadav, S. Rane, S. Shringare, M. Iguiniz, S. Heinisch, J. Lefevre, E. Corbel, N. Roques, Y. Vander Heyden, D. Guillarme, Ph. Hubert, First inter-laboratory study of a Supercritical Fluid Chromatographymethod for the determination of pharmaceutical impurities, Journal of Pharmaceutical and Biomedical Analysis, 161, 414-424 (2018).
A. Azzollini, L. Boggia, J. Boccard, B. Sgorbini, N. Lecoultre, P-M Allard, P. Rubiolo, S. Rudaz, K. Gindro, C. Bicchi and J-L Wolfender, Dynamics of Metabolite Induction in Fungal Co-cultures by Metabolomics at Both Volatile and Non-volatile Levels, Frontiers in Microbiology, 9, (2018).
F. Zuffereya, R. Rahban, A. Garciac, Y. Gagnebinc, J. Boccardc, D. Tonolic, F. Jeanneret, E. Stettler, A. Senn, S. Nef, S. Rudaz, R. Michel F., Steroid profiles in both blood serum and seminal plasma are not correlated and do not reflect sperm quality: Study on the male reproductive health of fifty young Swiss men, Clinical Biochemistry, 62, 39-46 (2018).
S. Rudaz, M. Feinberg, From method validation to result assessment: Established facts and pending questions, Trends in Analytical Chemistry, 105, 68-74 (2018).
N. Drouin, J. Pezzatti, Yoric Gagnebin, Víctor Gonzalez-Ruiz, Julie Schappler, Serge Rudaz*, Effective mobility as a robust criterion for compound annotation and identification in metabolomics: Toward a mobility-based library, Analytica Chimica Acta , 1032, 178 - 187 (2018).
V. Gonzalez-Ruiz, N. Drouin, S. Codesido, S. Rudaz, J. Schappler, ROMANCE: A new software tool to improve data robustness and feature identification in CE-MS metabolomics, Electrophoresis, , 1-11 (2018).

A. Goyon, A. Beck, J.-L. Veuthey, D. Guillarme, S. Fekete, Comprehensive study on the effect of sodium and potassium additives in size exclusion chromatographic separation of protein biopharmaceuticals, Journal of Pharmaceutical and Biomedical Analysis, 144, 242-251 (2017).
V. Desfontaines, A. Tarafder, J. Hill, J. Fairchild. A. Grand-Guillaume-Perrenoud, J.-L. Veuthey, D. Guillarme, A systematic investigation of sample diluents in modern supercriticalfluid chromat, Journal of Chromatography A, 1511, 122-131 (2017).
S. Fekete, J.-L. Veuthey, D. Guillarme, Achievable separation performance and analysis time in current liquid chromatographic practice for monoclonal antibody separations, Journal of Pharmaceutical and Biomedical Analysis, 141, 59-69 (2017).
A. Périat, D. Guillarme, J.-L. Veuthey, J. Boccard, S. Moco, D. Barron, A. Grand-Guillaume Perrenoud, Optimized selection of liquid chromatography conditions for widerange analysis of natural compounds, Journal of Chromatography A, 1504, 91-104 (2017).
D. Guillarme, J.-L. Veuthey, Alternative Strategies to Reversed-Phase Liquid Chromatography for the Analysis of Pharmaceutical Compounds, American Pharmaceutical Review, 20, 48-51 (2017).
D. Guillarme, J.-L. Veuthey, HPLC Teaching Assistant: A New Tool for Learning and Teaching Liquid Chromatography - Part I, LC GC europe, 30, 22-29 (2017).
B. Bobaly, G.M. Randazzo, S. Rudaz, J.-L. Veuthey D. Guillarme, S. Fekete, Optimization of non-linear gradient in hydrophobic interaction chromatography for the analytical characterization of antibody-drug conjugates, Journal of Chromatography A, 1481, 82-91 (2017).
A. Dispas, V. Desfontaine, B. Andri, P. Lebrun, D. Kotoni, A. Clarke, D. Guillarme, Ph. Hubert, Quantitative determination of salbutamol sulfate impurities using achiral supercritical fluid chromatography, Journal of pharmaceutical and biomedical analysis, 134, 170-180 (2017).
A. Goyon, D. Guillarme, S. Fekete, The importance of system band broadening in modern size exclusion chromatography, Journal of Pharmaceutical and Biomedical Analysis, 135, 50-60 (2017).
Y. Gagnebin, D. Tonoli, P. Lescuyer, B. Ponte, S. de Seigneux, P.-Y. Martin, J. Schappler, J. Boccard, S. Rudaz, Metabolomic analysis of urine samples by UHPLC-QTOF-MS: Impact of normalization strategies , Analytica Chimia Acta, 955, 27-35 (2017).
S. Fekete, I. Molnar, D. Guillarme, Separation of antibody drug conjugate species by RPLC: A genericmethod development approach, Journal of Pharmaceutical and Bioanalytical Analysis, 137, 60-69 (2017).
G.M. Randazzo, E. Vigneau, Ph. Courcoux, C. Harrouet, Y. Lijour, P. Dardenne, J. Boccard, S. Rudaz, Indirect quantitative structure-retention relationship for steroid identification: A chemometric challenge at “Chimiométrie 2016”, Chemometrics and Intelligent Laboratory Systems, 160, 52-58 (2017).
V. Desfontaine, J.-L. Veuthey, D. Guillarme, Hyphenated Detectors: Mass Spectrometry, Supercritical Fluid Chromatography - Handbook, xx, 213-243 (2017).
V. D'Atri, S. Fekete, A. Beck, M. Lauber, D. Guillarme, Hydrophilic Interaction Chromatography Hyphenated with Mass Spectrometry: A Powerful Analytical Tool for the Comparison of Originator and Biosimilar Therapeutic Monoclonal Antibodies at the Middle-up Level of Analysis, Analytical Chemistry, 89, 2086-2092 (2017).
E. Wagner-Rousset, S. Fekete, L. Morel-Chevillet, O. Colas, N. Corvaïa, S. Cianférani, D. Guillarme, A. Beck, Development of a fast workflow to screen the charge variants oftherapeutic antibodies, Journal of Chromatography A, 1498, 147-154 (2017).
B. Bobaly, V. D'Atri, A. Goyon, O. Colas, A. Beck, S. Fekete, D. Guillarme, Protocols for the analytical characterization of therapeutic monoclonal antibodies. II – Enzymatic and chemical sample preparation, Journal of Chromatography B, 1060, 325-335 (2017).
B. Bobaly, V. D'Atri, A. Beck, D. Guillarme, S. Fekete, Analysis of recombinant monoclonal antibodies in hydrophilicinteraction chromatography: A generic method developmentapproach, Journal of Pharmaceutical and Biomedical Analysis, 145, 24-32 (2017).
N. Guichard, D. Guillarme, P. Bonnabry, S. Fleury-Souverain, Antineoplastic drugs and their analysis: a state of the art review, Analyst , 142, 2273 (2017).
S. Fekete, R. Kormàny, D. Guillarme, Computer-Assisted Method Development for Small and Large Molecules, Recent Developments in HPLC and UHPLC, , 1-7 (2017).
A. Goyon, V. D'Atri, B. Bobaly, E. Wagner-Rousset, A. Beck, S. Fekete, D. Guillarme, Protocols for the analytical characterization of therapeutic monoclonal antibodies. I – Non-denaturing chromatographic techniques, Journal of Chromatography B, 1058, 73-84 (2017).
A. Bujard, C. Petit, P. - A. Carrupt, S. Rudaz , J. Schappler, HDM - PAMPA to predict gastrointestinal absorption, binding percentage, equilibrium and kinetics constant with human serum albumin and using 2 end-point measurements, Journal Pharmaceutical Sciences, 97, 143-150 (2017).
G. M. Randazzo, E. G. M. Randazzo, E. Vigneau, P. Courcoux, C. Harrouet, Y. Lijour, P. Dardenne, J. Boccard, S. Rudaz, Indirect Quantitative Structure- Retention Relationship for Steroid Identification: A chemometric challenge at “Chimiométrie 2016», Chem. Intel. Lab. Sys., 160, 52-58 (2017).
Y. Gagnebin, D. Tonoli, P. Lescuyer, B. Ponte, S. De Seigneux, P. - Y. Martin, J. Schappler, J. Boccard, S. Rudaz, Metabolomic analysis of urine samples by UHPLC-QTOF-MS: impact of normalization strategies, , Anal Chim. Acta, 955, 82-91 (2017).
P. Strajhar, D. Tonoli, F. Jeanneret, R. Imhof, V. Malagnino, M. Patt, D. Kratschma r, J. Boccard, S. Rudaz , A. Odermatt, Steroid profiling in H295R cells to identify chemicals potentially disrupting the production of adrenal steroids , Toxicology, 381, 51-63 (2017).
F. Ponzetto, J. Boccard, N. Baume, T. Kuuranne, S. Rudaz , M. Saugy, R. Nicoli, High resolution mass spectrometry as an alternative detection method to tandem mass spectrometry for the analysis of endogenous steroids in serum, Journal of Chromatography B, 1052, 34-42 (2017).
D. Guillarme, Analytical Characterization of Biopharmaceuticals, LCGC North America, 35 / 8, 496-499 (2017).
N. Drouin, J.-F. Mandscheff, S. Rudaz, J. Schappler, Development of a New Extraction Device Based on Parallel-Electromembrane Extraction, Analytical Chemistry, 89, 6346-6350 (2017).
V. D'Atri, E. Dumont, I. Van den heede, D. Guillarme, P. Sandra, K. Sandra, Hydrophilic Interaction Chromatography for the Characterization of Therapeutic Monoclonal Antibodies at Protein, Peptide, and Glycan Levels, LC GC Europe, 30 / 8, 424-434 (2017).
M. W. Dong, D. Guillarme, UHPLC, Part 2: Benefits, LC GC Europe, 30, 416-423 (2017).
M. W. Dong, D. Guillarme, UHPLC, Part II: Benefits, LC-GC North America, 35, 486-495 (2017).
R. Kormany, K. Tamas, D. Guillarme, S. Fekete, A workflow for column interchangeability in liquid chromatographyusing modeling software and quality-by-design principles, Journal of Pharmaceutical and Biomedical Analysis, 146, 220-225 (2017).
A. Goyon, V. D'Atri, O. Colas, S. Fekete, A. Beck, D. Guillarme, Characterization of 30 therapeutic antibodies and related products by size exclusion chromatography: Feasibility assessment for future mass spectrometry hyphenation, Journal of Chromatography B, 1065-1066, 35-43 (2017).
Y. Jacquot, D. Spaggiari. J. Schappler, E. Lesniewska, S. Rudaz, G. Leclerq, ERE-dependent transcription and cell proliferation: Independency of these two processes mediated by the introduction of a sulfone function into the weak estrogen estrothiazine, European Journal of Pharmaceutical Sciences, 109, 169-181 (2017).
G. S. M. Kammeijer, B. C. Jansen, I. Kohler, A. A. M. Heemskert, O. A. Mayboroda, P. J. Hensbergen, J. Schappler, M. Wuhrer, Sialic acid linkage differentiation of glycopeptides using capillary electrophoresis - electrospray ionization - mass spectrometry, Scientific Reports, 7:3733, 1-10 (2017).
A. Goyon, M. Excoffier, M.-C. Janin-Bussat, B. Bobaly, S. Fekete, D. Guillarme, A. Beck, Determination of isoelectric points and relative charge variants of 23 therapeutic monoclonal antibodies, Journal of Chromatography B, 1065-1066, 119-128 (2017).
A. Goyon, A. Beck, O. Colas, K. Sandra, D. Guillarme, S. Fekete, Evaluation of size exclusion chromatography columns packed withsub-3 um particles for the analysis of biopharmaceutical proteins, Journal of Chromatography A, 1498, 80-89 (2017).
G. M. Randazzo, D. Tonoli, P. Strajhar, I. Xenarios, A. Odermatt, J. Boccard, and S. Rudaz, Enhanced metabolite annotation via dynamic retention time prediction: Steroidogenesis alterations as a case study, Journal of Chromatography B, 1071, 11-18 (2017).

D. Guillarme, J.-L. Veuthey, HPLC Teaching Assistant: A New Tool for Learning and Teaching Liquid Chromatography, Part II. , LCGC North America, 34, 906-915 (2016).
R. Nicoli, D. Guillarme, N. Leuenberger, N. Baume, N. Robinson, M. Saugy, J.-L. Veuthey, Stratégies analytiques pour les contrôles antidopage: besoins, challenges et perspectives, Spectra biologie, 224, 45-54 (2016).
S. Fekete, J.-L. Veuthey, A. Beck, D. Guillarme, Hydrophobic interaction chromatography for the characterization of monoclonal antibodies and related products, Journal of Pharmaceutical and Biomedical Analysis, 130, 3-18 (2016).
D. Guillarme, J.-L. Veuthey, HPLC Teaching Assistant: A New Tool for Learning and Teaching Liquid Chromatography, Part I, LCGC North America, 32, 804-811 (2016).
J.-L. Veuthey, Particules superficiellement poreuses en chromatographie liquide, Techniques de l’ingénieur, 187, 1-9 (2016).
B. Bobaly, A. Beck, J.-L. Veuthey, D. Guillarme, S. Fekete, Impact of organic modifier and temperature on protein denaturation in hydrophobic interaction chromatography, Journal of Pharmaceutical and Biomedical Analysis, 131, 124-132 (2016).
E. Tyketa, J.-L. Veuthey, G. Desmet, D. Guillarme, S. Fekete, Computer assisted liquid chromatographic method development for the separation of therapeutic proteins, Analyst, 141, 5488-5507 (2016).
A. Periat, S. Fekete, A. Cusumano, J.-L. Veuthey, A. Beck, M. Lauber, and D. Guillarme, Potential of hydrophilic interaction chromatography for the analytical characterization of protein biopharmaceuticals, Journal of Chromatography A, 1448, 81-92 (2016).
A. Grand-Guillaume Perrenoud, D. Guillarme, J. Boccard, J.L. Veuthey, D. Barron, S. Moco, Ultra-high performance supercritical fluid chromatography coupled with quadrupole-time-of-flight mass spectrometry as a performing tool for bioactive analysis, Journal of Chromatography A, 1450, 101-111 (2016).
R. Nicoli, D. Guillarme, N. Leuenberger, N. Baume, N. Robinson, M. Saugy, J.-L. Veuthey, Stratégies analytiques pour les contrôles antidopage : besoins, challenges et perspectives, Spectra Analyse, 310, 42-53 (2016).
V. Desfontaine, L. Nováková, F. Ponzetto, R. Nicoli, M. Saugy, J.-L. Veuthey, D. Guillarme, Liquid chromatography and supercritical fluid chromatography as alternative techniques to gas chromatography for the rapid screening of anabolic agents in urine, Journal of Chromatography A, 1451, 145-155 (2016).
M. Mignot, A. Périat, V. Peulon-Agasse, P. Cardinael, J.-L. Veuthey, D. Guillarme, Evaluation of thermally pretreated silica stationary phases under hydrophilic interaction chromatography conditions, Journal of Separation Sciences, 39, 1611-1618 (2016).
L. Nováková, V. Desfontaine, F. Ponzetto, R. Nicoli, M. Saugy, J.-L. Veuthey, D. Guillarme, Fast and sensitive supercritical fluid chromatography - tandem mass spectrometry multi-class screening method for the determination of doping agents in urine, Analytica Chimica Acta, 915, 102-110 (2016).
A. Périat, I. Kohler, A. Thomas, R. Nicoli, J. Boccard, J.-L. Veuthey, J. Schappler, D. Guillarme, Systematic evaluation of matrix effects in hydrophilic interaction chromatography versus reversed phase liquid chromatography coupled to mass spectrometry, Journal of Chromatography A, 1439, 42-53 (2016).
V. Desfontaine, J.-L. Veuthey, D. Guillarme, Evaluation of innovative stationary phase ligand chemistries and analytical conditions for the analysis of basic drugs by supercritical fluid chromatography, Journal of Chromatography A, 1438, 244 - 253 (2016).
R. Nicoli, D. Guillarme, N. Leuenberger, N. Baume, N. Robinson, M. Saugy, J.-L. Veuthey, Analytical Strategies for Doping Control Purposes: Needs, Challenges and Perspectives, Analytical Chemistry, 88, 508-523 (2016).
S. Fekete, M. Rodriguez-Aller, A. Cusumano, R. Hayes, H. Zhang, T. Edge, J.-L. Veuthey, D. Guillarme, Prototype sphere-on-sphere silica particles for the separation of large biomolecules, Journal of Chromatography A, 1431, 94-102 (2016).
N. Drouin, S. Rudaz, J. Schappler, Dynamic-Electromembrane Extraction: A Technical Development for the Extraction of Neuropeptides, Analytical Chemistry, 88, 5308-5315 (2016).
V. Gonzalez-Ruiz, S. Codesido, J. Far, S. Rudaz, J. Schappler, Evaluation of a new low sheath–flow interface for CE-MS, Electrophoresis, 37, 936-946 (2016).
M. Rodriguez-Aller, D. Guillarme, A. Beck, S. Fekete, Practical method development for the separation of monoclonalantibodies and antibody-drug-conjugate species in hydrophobicinteraction chromatography, part 1: optimization of the mobile phase, Journal of Pharmaceutical and Biomedical Analysis, 118, 393-4.3 (2016).
A. Cusumano, D. Guillarme, A. Beck, S. Fekete, Practical method development for the separation of monoclonalantibodies and antibody-drug-conjugate species in hydrophobicinteraction chromatoraphy, part 2: Optimization of the phase system, Journal of Pharmaceutical and Biomedical Analysis, 121, 161-173 (2016).
S. Romand, S. Rudaz, D. Guillarme, Separation of substrates and closely related glucuronide metabolitesusing various chromatographic modes, Journal of Chromatography A, 1435, 54-65 (2016).
G. M. Randazzo, D. Tonoli, S. Hambye, D. Guillarme, F. Jeanneret, A. Nurisso, L. Goracci, J. Boccard, Prediction of retention time in reversed-phase liquid chromatography as a tool for steroid identification, Analytica Chimica Acta, 916, 8-16 (2016).
S. Fekete, J. Fekete, D. Guillarme, Korszer? méretkizárásos kromatográfia: fehérje aggregátumok elválasztása, Kromatografus - kromatografiai folyoirat, , 7-10 (2016).
S. Fekete, D. Guillarme, P. Sandra, K. Sandra, Chromatographic, Electrophoretic, ans Mass Spectrometric Methods for the Analytical Characterization of Protein Biopharmaceuticals, Analytical Chemistry, 88, 480-507 (2016).
F. Jeanneret, D. Tonoli, D. Hochstrasser, J.-H. Saurat, O. Sorge, J. Boccard, S. Rudaz, Evaluation and identification of dioxin exposure biomarkers in human urine by high-resolution metabolomics, multivariate analysis and in vitro synthesis. , Toxico Letter, 240 (1), 22-31 (2016).
F. Jeanneret, D. Tonoli, M. Rossier, M. Saugy, J. Boccard, S. Rudaz, Evaluation of steroidomics by liquid chromatography hyphenated to mass spectrometry as a powerful analytical strategy for measuring human steroid perturbations, Journal of Chromatography A, 1430, 97-112 (2016).
F. Ponzetto, F. Mehl, J. Boccard, N. Baume, S. Rudaz, M. Saugy, N. Nicoli, Longitudinal monitoring of endogenous steroids in human serum by UHPLC-MS/MS as a tool to detect testosterone abuse in sport, Analytical and Bioanalytical Chemistry, 408 (3), 705-719 (2016).
S. Bertrand, A. Azzollini, A. Nievergelt, J. Boccard, M. Cuendet, J.-L. Wolfender, Statistical correlations between HPLC activity-based profiling results ans NMR/MS microfractions data to deconvolute bioactive compounds in mixture., Molecules, 21 (3), 259 (2016).
J. Boccard, S. Rudaz, Exploring Omics data from designed experiments using Analysis of Variance Multiblock Orthogonal Partial Least Squares, Analytica Chimica Acta, 920, 18-28 (2016).
E. Jaccoulet, J. Boccard, M. Taverna, A. Santos Azevedos, S. Rudaz, C. Smadja, High throughput identification of monoclonal antibodies after compounding by UV spectroscopy coupled to chemometrics analysis, Analytical and Bioanalytical Chemistry, , (2016).
D. Spaggiari, Y. Daali, S. Rudaz, An extensive cocktail approach for rapid risk assessment of in vitro CYP450 direct reversible inhibition by xenobiotic exposure. , Pharmacol., 302, 41-51 (2016).
A. Hammer, S. Rudaz, S. Ginchard, S. Kling, D. Tabibian, O. Richoz, F. Hafezi, Analysis of riboflavin compounds in the rabbit cornea in vivo, Curr. Exes Res., 41, 1-7 (2016).
C. Diez, M. Feinberg, A. Staub Spörri, E. Cognard, D. Ortelli, P. Edder, S. Rudaz, Evaluation of quantification methods to compensate for matrix effects in the analysis of Benzalkonium chloride and Didecyldimethylammonium chloride in fruits and vegetables by LC-ESI-MS/MS, Food Anal. Meth., 9, 485-499 (2016).
O. Sarr, E.H.A. Diop, A. Diop, A.G.S. Atouni, S.M. Ndiaye, C.A. Wafo Tchounga, R. Gueye, K. Thiam, T.M. Wane, A. Sarr, B. Ndiaye, S. Rudaz, Y.M. Diop, Development and validation of a capillary electrophoresis method for quality assessment of metronidazole-based drugs, Int. J. Modern Anal Sep. Sci., 5, 1-11 (2016).
N. Marsousi, C.F. Samer, P. Fontana, J.L. Reny, S. Rudaz, J.A. Desmeules, Y. Daali, Coadministration of Ticagrelor and Ritonavir: Toward Prospective Dose djustment to Maintain an Optimal Platelet Inhibition Using the PBPK Approach, Clinical Pharmacology and Therapeutics, 100, 295-304 (2016).
N. Marsousi, F. Doffey-Lazeyras, S. Rudaz, J.A. Desmeules, Y. Daali, Intestinal permeability and P-glycoprotein-mediated efflux transport of ticagrelor in Caco-2 monolayer cells, Fundamental and Clinical Pharmacology, , 1-8 (2016).
M. Sorensen, D.C. Harmes, D. R. Stoll, G. O. Staples, S. Fekete, D. Guillarme, A. Beck, Comparison of originator and biosimilar therapeutic monoclonal antibodies using comprehensive two-dimensional liquid chromatography coupled with time-of-flight mass spectrometry, MABS, 8, 1224-1234 (2016).
M. Rodriguez-Aller, A. Cusumano, A. Beck, D. Guillarme, S. Fekete, Importance of vial shape and type on the reproducibility of sizeexclusion chromatography measurement of monoclonal antibodies, Journal of Chromatography B, 1032, 131-138 (2016).
A. Azzollini, Q. Favre-Godal, J. Zhang, L. Marcourt, S. N. Ebrahimi, S. Wang, P. Fan, H. Lou, D. Guillarme, E. Ferreira Queiroz, J.-L. Wolfender, Preparative Scale MS-Guide Isolation of Bioactive Compounds Using High-Resolution Flash Chromatography: Antifungal from Chiloscyphux polyanthos as a Case Study, Planta Med, 82, 1051-1057 (2016).

M. Rodriguez-Aller, D. Guillarme, J.-L. Veuthey, R. Gurny, Strategies for formulating and delivering poorly water-soluble drugs, Journal of Drug Delivery Science and Technology, 30, 342-351 (2015).
M. Rodriguez-Aller, S. Guinchard, D. Guillarme, M. Pupier, D. Jeannerat, E. Rivara-Minten, J.-L. Veuthey, R. Gurny, New prostaglandin analog formulation for glaucoma treatment containing cyclodextrins for improved stability, solubility and ocular tolerance, European Journal of Pharmaceutics and Biopharmaceutics, 95, 203-214 (2015).
S. Fekete, J.L. Veuthey, D. Guillarme, Modern column technologies for the analytical characterization of biopharmaceuticals in various liquid chromatographic modes, LC-GC Europe, supplément, 8-15 (2015).
S. Fekete, A. Beck, J.L. Veuthey, D. Guillarme, Ion exchange chromatography for the characterization of biopharmaceuticals, Journal of Pharmaceutical and Biomedical Analysis, 113, 43-55 (2015).
S. Fekete, J.-L. Veuthey, D. Guillarme, Comparison of the most recent chromatograpohic approaches applied for fast and high resolution separations: Theory and practice, Journal of Chromatography A, 1408, 1-14 (2015).
M. Hanafi, S. S. Ouertani, J. Boccard, G. Mazerolles, S. Rudaz, Multi-way PLS regression: Monotony convergence of tri-linear PLS2 and optimality of parameters, Computational Statistics and Data Analysis, 83, 129-139 (2015).
B. Bobaly, D. Guillarme, S. Fekete, Evaluation of new superficially porous particles with carbon core andnanodiamond–polymer shell for proteins characterization, Journal of Pharmaceutical and Biomedical Analysis, 104, 130-136 (2015).
S. Fekete, A. Beck, J. Fekete, D. Guillarme, Method development for the separation of monoclonal antibodycharge variants in cation exchange chromatography, Part II: pHgradient approach, Journal of Pharmaceutical and Biomedical Analysis, 102, 282-289 (2015).
S. Fekete, A. Beck, J. Fekete, D. Guillarme, Method development for the separation of monoclonal antibodycharge variants in cation exchange chromatography, Part I: Saltgradient approach, Journal of Pharmaceutical and Biomedical Analysis, 102, 33-44 (2015).
L. Nováková , A. Grand-Guillaume Perrenoud , R. Nicoli , M. Saugy , J.-L. Veuthey , D. Guillarme, Ultra high performance supercritical fluid chromatography coupled with tandem mass spectrometry for screening of doping agents. I: Investigation of mobile phase and MS conditions, Analytica Chimica Acta , 853, 637-646 (2015).
S. Fekete, A. Beck, E. Wagner, K. Vuignier, D. Guillarme, Adsorption and recovery issues of recombinant monoclonal antibodies in reversed-phase liquid chromatography, J. Sep. Sci., 38, 1-8 (2015).
A. Périat, I. S. Krull, D. Guillarme, Applications of hydrophilic interaction chromatography to amino acids, peptides, and proteins, J. Sep. Sci. , 38, 357-367 (2015).
B. Bobály , A. Beck , J. Fekete, D. Guillarme , S. Fekete, Systematice valuation o fmobile phase additives for the LC%u2013MS characterization o ftherapeutic proteins, Talanta, 136, 60-67 (2015).
E.Tyteca, V.Desfontaine, G.Desmet, D. Guillarme, Possibilities of retention modeling and computer assisted methoddevelopment in supercritical fluid chromatography, Journal of Chromatography A, 1381, 219-228 (2015).
M. W. Dong, D. Guillarme, S. Fekete, R. Rangelova, J. Richards, D. Prudhomme, N. P. Chetwyn, Analysis of Complex Pharmaceuticals by Ultrahigh- Pressure Liquid Chromatography: Case Studies and Quality Control Implications, LC-GC Europe, 28, 88-97 (2015).
D. R. Stoll, D. C. Harmes, J. Danforth, E. Wagner, D. Guillarme, S. Fekete, A. Beck, Direct Identification of Rituximab Main Isoforms and Subunit Analysis by Online Selective Comprehensive TwoDimensional Liquid Chromatography-Mass Spectrometry, Analytical Chemistry, 87, 8307-8315 (2015).
C. Diez, D. Guillarme, A. Staub-Spörri, E. Cognard, D. Ortelli, P. Edder, S. Rudaz, Aminoglycoside analysis in food of animal origin with a switterionic stationary phase and liquid chromatography-tandem mass spectrometry, Analytica Chimia Acta, 882, 127-139 (2015).
S. Fekete, D. Guillarme, Estimation of pressure-, temperature- and frictional heating-related effects on proteins' retention under ultra-high-pressure liquid chromatographic conditions, Journal of Chromatography A, 1393, 73-80 (2015).
S. Fekete, A. Beck, D. Guillarme, Characterization of cation exchanger stationary phases applied for the separations of therapeutic monoclonal antibodies, Journal of Pharmaceutical and Biomedical Analysis, 111, 169-176 (2015).
J. Gradinaru, S. Romand, L. Geiser, P.-A. Carrupt, D. Spaggiari, S. Rudaz, Inhibition screening method of microsomal UGTs using the cocktail approach , Eur. J. Pharm. Sci, 71, 35-45 (2015).
F. Mehl, G. Marti, P. Merle, E. Delort, L. Baroux, H. Sommer, J.-L. Wolfender, S. Rudaz, J. Boccard, Integrating metabolomic data from multiple analytical platforms for a comprehensive characterisation of lemon essential oils , Flavour Fragr. J, 30, 131-138 (2015).
S. Fleury-Souverain, M. Mattiuzzo, F. Mehl, S. Nussbaumer, L. Bouchoud, L. Falaschi, M. Gex-Fabry, S. Rudaz, F. Sadeghipour, P. Bonnabry, Evaluation of chemical contamination of surfaces during the preparation of chemotherapies in 24 hospital pharmacies, European Journal of Hospital Pharmacy, xxx, xxx (2015).
D. Tonoli, C. Fürstenberger, J. Boccard, D. Hochstrasser, F. Jeanneret, A. Odermatt, S. Rudaz, Steroidomic footprinting based on ultra-high performance liquid chromatography coupled with qualitative and quantitative high-resolution mass spectrometry for the evaluation of endocrine disrupting chemicals in H295R cells, Chemical Research in Toxicology , 28, 955-966 (2015).
F. Montecucco, S. Lenglet, F. Carbone, S. Boero, G. Pelli, F. Burger, M. Bertolotto, A. Nencioni, F. Dallegri, R. A. Fraga-Silva, L. Fougere, C. Elfakir, A.-L. Gassner, S. Rudaz, N. Vuilleumier, A. Poggi, F. Mach, Treatment with KLEPTOSE® CRYSMEB reduces atherogenesis in ApoE-/- mice impacting serum lipid profile and Th1 lymphocyte-mediated inflammation, Vascular Pharmacology, 72, 197-208 (2015).
C. Diez, M. Feinberg, A. Staub Sporri, E. Cognard, D. Ortelli, P. Edder, S. Rudaz , Evaluation of quantification methods to compensate for matrix effects in the analysis of Benzalkonium chloride and Didecyldimethylammonium chloride in fruits and vegetables by LC-ESI-MS/MS, Food Analytical Methods , xxx, xxx (2015).
M. Anastasi, S. Rudaz, T. Queruau Lamerie, P. Odou, P. Bonnabry, S. Fleury-Souverain, Efficacy of Two Cleaning Solutions for the Decontamination of 10 Antineoplastic Agents in the Biosafety Cabinets of a Hospital Pharmacy, Ann. Occup. Hyg., 59, 895-908 (2015).
F. Jeanneret, D. Tonoli, D. Hochstrasser, J.-H. Saurat, O. Sorg, J. Boccard, S. Rudaz, Evaluation and identification of dioxin exposure biomarkers in human urine by high-resolution metabolomics, multivariate analysis and in vitro synthesis, Toxicology Letters, xxx, xxx (2015).
A. Hammer, S. Rudaz, S. Guinchard, S. Kling, D. Tabibian, O. Richoz, F. Hafezi, Analysis of riboflavin compounds in the rabbit cornea in vivo, Current Eye Research, xxx, xxx (2015).
F. Jeanneret, D. Tonoli, M. Rossier, M. Saugy, J. Boccard, S Rudaz, Evaluation of steroidomics by liquid chromatography hyphenated to mass spectrometry as a powerful analytical strategy for measuring human steroid perturbations, J. Chromatogr. A, xxx, xxx (2015).
A. Bujard, H. Voirol, P.-A. Carrupt, J. Schappler, Modification of a PAMPA model to predict passive gastrointestinal absorption and plasma protein binding, European Journal of Pharmaceutical Sciences, 77, 273-278 (2015).
V. Desfontaine, L. Nováková, D. Guillarme, SFC-MS vs. RPLC-MS for drug analysis in biological samples?, Bioanalysis, 7, 1193-1195 (2015).
S. Fekete, A. Beck, D. Guillarme, Chromatographic characterization of biopharmaceuticals: recent trends and new tools, American Pharmaceutical Review, American Pharmaceutical Review, 18, 59-63 (2015).
B. Bobaly, Z. Marta, J. Fekete, D. Guillarme, S. Fekete, chromatography columns in the separation of protein variants, Current Chromatography, 2, 136-144 (2015).
S. Fekete, A. Beck, J.L. Veuthey, D. Guillarme, Ion exchange chromatography for the characterization of biopharmaceuticals, Journal of Pharmaceutical and biomedical analysis, 113, 43-55 (2015).
V. Desfontaine, D. Guillarme, E. Francotte, L. Novakova, Supercritical fluid chromatography in pharmaceutical analysis, Journal of Pharmaceutical and biomedical analysis, 113, 56-71 (2015).
S. Fekete, D. Jensen, J. Zukowski, D. Guillarme, Evaluation of a new wide-pore superficially porous material with carbon core and nanodiamond-polymer shell for the separation of proteins, Journal of Chromatography A, 1414, 51-59 (2015).
S. Fekete, J.L. Veuthey, D. Guillarme, Modern column technologies for the analytical characterization of biopharmaceuticals in various chromatographic modes, LC-GC Europe, Supplement, 8-15 (2015).
M. Rodriguez-Aller, S. Guichard, D. Guillarme, M. Pupier, D. Jeannerat, E. Rivara-Minten, J.L. Veuthey, R. Gurny, New prostaglandin analog formulation for glaucoma treatment containing cyclodextrins for improved stability, solubility and ocular tolerance, European Journal of Pharmaceutics and Biopharmaceutics, 95, 203-214 (2015).
C. Diez, D. Guillarme, A. Staub Spörri, E. Cognard, D. Ortelli, P. Edder, S. Rudaz, Aminoglycoside analysis in food of animal origin with a zwitterionic stationary phase and liquid chromatography–tandem mass spectrometry, Analytica Chimia Acta, 882, 127-139 (2015).

J. Boccard, F. Badoud, N. Jan, R. Nicoli, C. Schweizer, F. Pralong, J.-L. Veuthey, N. Baume, S. Rudaz, M. Saugy, Untargeted profiling of urinary steroid metabolites after testosterone ingestion: opening new perspectives for antidoping testing, Bioanalysis, 6, 2523-2536 (2014).
L. Novakova, M. Rentsch, A. Grand-Guillaume-Perrenoud, R. Nicoli, M. Saugy, J.-L. Veuthey, D. Guillarme, Ultra high performance supercritical fluid chromatography coupled with tandem mass spectrometry for screening of doping agents. II: Analysis of biological samples, Analytica Chimica Acta, 853, 647-659 (2014).
L. Novakova, M. Rentsch, A. Grand-Guillaume-Perrenoud, R. Nicoli, M. Saugy, J.-L. Veuthey, D. Guillarme, Ultra high performance supercritical fluid chromatography coupled with tandem mass spectrometry for screening of doping agents. I: Investigation of mobile phase and MS conditions, Analytica Chimica Acta, 853, 637-646 (2014).
A. Grand-Guillaume-Perrenoud, J.-L. Veuthey, D. Guillarme, The use of columns packed with sub-2um particles in supercritical fluid chromatography, Trends in Analytical Chemistry, 63, 44-54 (2014).
S. Fekete, J. Schappler, J.-L. Veuthey, D. Guillarme, Current and future trends in UHPLC, Trends in Analytical Chemistry, 63, 2-14 (2014).
S. Fekete, A. Beck, J.-L. Veuthey, D. Guillarme, Theory and practice of size exclusion chromatography for the analysis of protein aggregates, Journal of Pharmaceutical and Biomedical Analysis, 101, 161-173 (2014).
S. Romand, J. Schappler, J.-L. Veuthey, P.-A. Carrupt, S. Martel, cIEF for rapid pKa determination of small molecules: A proof of concept, European Journal of Pharmaceutical Sciences, 63, 14-21 (2014).
A. Grand-Guillaume-Perrenoud, J.-L. Veuthey, D. Guillarme, Coupling state-of-the-art supercritical fluid chromatography and mass spectrometry: from hyphenation interface optimization to high-sensitivity analysis of pharmaceutical compounds, J. Chromatogr A, 1339, 174-184 (2014).
M. Naldi, J. Fiori, R. Gotti, A. Périat, J.-L. Veuthey, D. Guillarme, V. Andrisano, UHPLC determination of catechins for the quality control of green tea., Journal of Pharmaceutical and Biomedical Analysis, 88, 307-314 (2014).
C. Temporini, R. Nicoli, A. Tiengo, N. Barbarini, E. Calleri, M. Galliano, P. Magni, S. Rudaz, J.-L. Veuthey, L. Regazzoni, G. Aldini, G. Massolini, Online Microreactor Titanium Dioxide RPLC-LTQ-Orbitrap MS Automated Platform for Shotgun Analysis of (Phospho) Proteins in Human Amniotic Fluid, Chromatographia, 77, 39-50 (2014).
E. Dahmane, J. Boccard, C. Csajka, S. Rudaz, L. Decosterd, E. Genin, B. Duretz, M. Bromirski, K. Zaman, B. Testa, B. Rochat, Quantitative monitoring of tamoxifen in human plasma extended to 40 metabolites using liquid-chromatography high-resolution mass spectrometry: new investigation capabilities for clinical pharmacology, Anal Bioanal Chemistry, 11, 1 (2014).
F. Jeanneret, J. Boccard, C. Csajka, S. Rudaz, L. Decosterd, E. Genin, B. Duretz, M. Bromirski, K. Zaman, B. Testa, B. Rochat, Human urinary biomarkers of dioxin exposure: analysis by metabolomics and biologivally-driven data dimentionality reduction, Anal Bioanal Chemistry, xx, xx (2014).
G. Bonvin, J. Schappler, S. Rudaz, Nonaqueous capillary electrophoresis for the analysis of acidic compounds using negative electrospray ionization mass spectrometry, J. Chromatogr A, 1323, 163-173 (2014).
J. Boccard, S. Rudaz, Harnessing the complexity of metabolomic data with checometrics, J. Chemometrics, 28, 1-9 (2014).
G. Bonvin, S. Rudaz, J. Schappler, In-spray supercharging of intact proteins by capillary electrophoresis-mass spectrometry using a sheath liquid interface, Analytica Chimica Acta, 813, 97-105 (2014).
G. Marti, J. Boccard, F. Mehl, B. Debrus, L. Marcourt, Ph. Merle, E. Delors, L. Baroux, H. Sommer, S. Rudaz, J.-L. Wolfender, Comprehensive profiling and marker identification in non-volatile citrus oil residues by mass spectrometry and nuclear magnetic resonance, Food Chemistry, 150, 235-245 (2014).
B. Bobaly, D. Guillarme, S. Fekete, Systematic comparison of a new generation of columns packed with sub-2 um superficially porous particles, J. Sep. Sci., 37, 189-197 (2014).
S. Fekete, I. Kohler, S. Rudaz, D. Guillarme, Importance of instrumentation for fast liquid chromatography in pharmaceutical analysis, Journal of Pharmaceutical and Biomedical Analysis, 87, 105-119 (2014).
F. Mehl, G. Marti, J. Boccard, B. Debrus, Ph. Merle, E. Delort, L. Baroux, V. Raymo, M. I. Velazco, H. Sommer, J.-L. Wolfender, Differentiation of lemon essential oil based on volatile and non-volatile fractions with various analytical techniques: a metabolomic approach, Food Chemistry, 143, 325-335 (2014).
S. Fekete, A. Grand-Guillaume-Perrenoud, D. Guillarme, Evolution and Current Trends in Liquid and Supercritical Fluid Chromatography, Current Chromatography, 1, 15-40 (2014).
R. Kormany, J. Fekete, D. Guillarme, S. Fekete, Reliability of simulated robustness testing in fast liquid chromatography, using stete-of-the-art column technology, instrumentation and modelling software, Journal of Pharmaceutical and Biomedical Analysis, 89, 67-75 (2014).
R. Kormany, J. Fekete, D. Guillarme, S. Fekete, Reliability of simulated robustness testing in fast liquid chromatography, using stete-of-the-art column technology, instrumentation and modelling software, Journal of Pharmaceutical and Biomedical Analysis, 89, 67-75 (2014).
G. Bonvin, S. Rudaz, J. Schappler, In-spray supercharging of intact proteins by capillary electrophoresis-mass spectrometry using a sheath liquid interface, Analytica Chimica Acta, 813, 97-105 (2014).
E. Tyteca, A. Périat, S. Rudaz, G. Desmet, D. Guillarme, Retention modeling and method development in hydrophilic interaction chromatography, J. Chromatogr A, 1337, 116-127 (2014).
D. Guillarme, S. Fekete, Advantages and Applications of Revolutionary Superficially Porous Particle Columns in Liquid Chromatography, PerkinElmer publication, xx, xx (2014).
D. Guillarme, Evolutions majeures en chromatographie liquides, Techniques de l'ingénieur, p1494, 1-13 (2014).
I. Kohler, M. Augsburger, S. Rudaz, J. Schappler, New insights in carbohydrate-deficient transferrin analysis with capillary electrophoresis-mass spectrometry, Forensic Science International, 243, 14-22 (2014).
L. Novakova, A. Grand-Guillaume-Perrenoud, I. François, C. West, E. Lesellier, D. Guillarme, Modern analytical supercritical fluid chromatography using columns packed with sub-2um particles: A tutorial, Analytica Chimica Acta, 824, 18-35 (2014).
A.-L. Gassner, J. Schappler, M. Feinberg, S. Rudaz, Derivation of uncertainty functions from validation studies in biological fluids: Application to the analysis of caffeine and its major metabolites in human plasma samples, J. Chromatogr A, 1353, 121-130 (2014).
S. Fekete, D. Guillarme, Superficially Porous Particles: Perspectives, Practices, and Trends, LCGC North America, 32/6, xx (2014).
I. Kohler, D. Guillarme, Multi-target screening of biological samples using LC-MS/MS: focus on chromatographic innovations, Bioanalysis, 6(9), 1255-1273 (2014).
S. S. Ouertani, G. Mazerolles, J. Boccard, S. Rudaz, M. Hanafi , Multi-way PLS for discrimination: Compact form equivalent to the tri-linear PLS2 procedure and its monotony convergence, Chemometr. Intell. Lab, 133, 25-32 (2014).
M. W. Dong, D. Guillarme, S. Fekete, R. Rangelova, J. Richards, D. Prudhomme, N. P. Chetwyn, Analysis of Complex Pharmaceuticals by Ultrahigh-Pressure Liquid Chromatography: Case Studies and Quality Control Implications, LCGC NORTH AMERICA, 32, 1-8 (2014).
A. Périat, I. Kohler, A. Bugey, S. Bieri, F. Versace, C. Staub, D. Guillarme, Hydrophilic interaction chromatography versus reversed phase liquid chromatography coupled to mass spectrometry: Effect of electrospray ionization source geometry on sensitivity, J. Chromatogr A, 1356, 211-220 (2014).
D. Guillarme, HILIC: The Pros and Cons, The Column, 10, 17 (2014).
E. Tateca, D. Guillarme, G. Desmet, Use of individual retention modeling for gradient optimization inhydrophilic interaction chromatography: Separation of nucleobasesand nucleosidesEva, J. Chromatogr A, 1368, 125-131 (2014).
R. Kormany, I. Molnar, J. Fekete, D. Guillarme, S. Fekete, Robust UHPLC Separation Method Development for Multi‑API Product Containing Amlodipine and Bisoprolol: The Impact of Column Selection, Chromatographia, 77, 1119-1127 (2014).
P. J. Eugster, J. Boccard, B. Debrus, L. Bréant, J.-L. Wolfender, S. Martel, P.-A. Carrupt, Retention time prediction for dereplication of natural products (CxHyOz) in LC–MS metabolite profiling, Phytochemistry, 108, 196-207 (2014).
D. Spaggiari, F. Mehl, V. Desfontaine, A. Grand-Guillaume-Perrenoud, S. Fekete, S. Rudaz, D. Guillarme, Comparison of liquid chromatography and supercritical fluidchromatography coupled to compact single quadrupole massspectrometer for targeted in vitro metabolism assay, J. Chromatogr A, 1371, 244-279 (2014).
S. Fekete, D. Guillarme, Ultra-high-performance liquid chromatography for the characterization of therapeutic proteins, Trends in Analytical Chemistry, 63, 76-84 (2014).
A. Grand-Guillaume-Perrenoud, W. P. Farrell, C. M. Aurigemma, N. C. Aurigemma, S. Fekete, D. Guillarme, Evaluation of stationary phases packed with superficially porousparticles for the analysis of pharmaceutical compounds usingsupercritical fluid chromatography, J. Chromatogr A, 1360, 275-287 (2014).
F. Jeanneret, J. Boccard, F. Badoud, O. Sorg, D. Tonoli, D. Pelclova, S. Vlckova, D. N. Rutledge, C. F. Samer, D. Hochstrasser, J.-H. Saurat, S. Rudaz, Human urinarybiomarkersofdioxinexposure:Analysisby metabolomics andbiologicallydrivendatadimensionalityreduction, Toxicology Letters, 230, 234-243 (2014).
D. Spaggiari, L. Geiser, S. Rudaz, Coupling ultra-high-pressure liquid chromatography with mass spectrometry for in vitro drug metabolism studies, Trends in Analytical Chemistry, 63, 129-139 (2014).
D. Spaggiari, L. Geiser, Y. Daali, S. Rudaz, A cocktail approach for assessing the in vitro activity of human cytochrome P450s: An overview of current methodologies, Journal of Pharmaceutical and Biomedical Analysis, 101, 221-237 (2014).
D. Spaggiari, L. Geiser, Y. Daali, S. Rudaz, Phenotyping of CYP450 in human liver microsomes using the cocktail approach, Analitical and Bioanalytical Chemistry, 406, 4875-4887 (2014).
F. Been, L. Rossi, C. Ort, S. Rudaz, O. Delémont, P. Esseiva, Population Normalization with Ammonium (NH4-N) in Wastewater-Based Epidemiology: Application to Illicit Drugs Monitoring, Environ. Sci. Technol, xx, xx (2014).
R. Kormany, J. Fekete, D. Guillarme, S. Fekete, Reliability of computer-assisted method transfer between several column demensions packed with 1.3 - 5 um core-shell particles and between various instruments, Journal of pharmaceutical and biomedical analysis, 94, 188-195 (2014).
F. Mehl, G. Marti,Ph. Merle, E. Delort, L. Baroux, H. Sommer, J.-L. Wolfender, S. Rudaz J. Boccard, Integrating metabolomic data from multiple analytical platforms for a comprehensive characterisation of lemon essential oils, Flavor and Fragrance Journal, 1 (on line), 1-8 (2014).
S. Fekete, M.W. Dong, D. Guillarme, Superficially Porous Particles: Perspectives, Practices and Trend, LC-GC North America, 32, 420-433 (2014).
J. Schappler, E. Reginato, El H. A. Diop. S. Rudaz, Analyse qualitative et quantitative de contrefaçons par electrophorèse capillaire, une approche intégrée par la technique de la double injection, Spectra Analyse, 298, 63-73 (2014).
S. Cretton, T.A. Bartholomeusz, F. Mehl, E. Delort, L. Baroux, V. Raymo, M.I. Velazco, H. Sommer, J.-L. Wolfender, S. Rudaz, Synthesis and In Vitro Evaluation of Tropane Halogenated-derivatives against Malaria, Sleeping Sickness, Chagas Disease and Leishmaniasis, Medicinal Chemistry, 10 (8), 753-758 (2014).
G. Bonvin, J. Schappler, S. Rudaz, Non-aqueous capillary electrophoresis for the analysis of pharmaceutical acidic compounds using negative ESI-MS, Chimia, 68, 665 (2014).
S. Fekete, J. Schappler, J.-L. Veuthey, D. Guillarme, Current and futur trends in UHPLC, Trends in Analytical Chemistry, 62, 2-13 (2014).
C. Samer, N. Marsousi, Y. Daali, S. Rudaz, L. Almond, H. Humphries, J. Desmeules, Prediction of metabolicinteractions with oxycodone via CYP2D6 and CYP3A inhibition using a physiologically-based pharmacokinetic model, CPT: Pharmacometrics & Systems Pharmacology, 3, 1-8 (2014).

K. Vuignier, J.-L. Veuthey, P.-A. Carrupt, J. Schappler, Global analytical strategy to measure drug-plasma protein interactions: from high-throughput to in-depth analysis, Drug Discovery Today, 18, 21-22 (2013).
K. Vuignier, J.L. Veuthey, P.-A. Carrupt, J. Schappler, Highlights of Analytical Sciences in Switzerland, Chimia, 67 N° 10, 739 (2013).
T. Bortolotto, D. Guillarme, D. Gutemberg, J.-L. Veuthey, I. Krejci, Composite resin vs resin cement for luting of indirect restorations: Comparison of solubility and shrinkage behavior, Dental Materials Journal, 32(5), 834-838 (2013).
A. Grand-Guillaume-Perrenoud, Ch. Hamman, M. Goel, J.-L. Veuthey, D. Guillarme, S. Fekete, Maximizing kinetic performance in supercritical fluid, J. Chromatogr. A, 1314, 288-297 (2013).
A. Periat, J. Boccard, J.-L. Veuthey, S. Rudaz, D. Guillarme, Systematic comparison of sensitivity between hydrophilic interaction liquid chromatography and reversed phase liquid chromatography coupled with mass spectrometry, J. Chromatogr. A, 1312, 49-57 (2013).
D. Spaggiari, S. Fekete, P. Eugster, J.-L. Veuthey, L. Geiser, S. Rudaz, D. Guillarme, Contribution of various types of liquid chromatography-mass spectrometry instruments to band broadening in fast analysis, J. Chromatogr. A, 1310, 45-55 (2013).
K. Vuignier, S. Fekete, P.-A. Carrupt, J.-L. Veuthey, D- Guillarme, Comparison of various silica-based monoliths for the analysis of large biomolecules, Journal of Separation Science, 36, 2231-2243 (2013).
M. Rodriguez-Aller, D. Guillarme, M. El Sanharawi, F. Behar-Cohen, J.-L. Veuthey, R. Gurny, In vivo distribution and exvivo permeation of cyclosporine A prodrug aqueous formulations for ocular application, Journal of Controlled Release, 170, 153-159 (2013).
A. Periat, I. Kohler, J.-L. Veuthey, D. Guillarme, Advances in Hydrophilic Interaction Liquid Chromatography for Pharmaceutical Analysis, LCGC Europe, May 2013, 17-23 (2013).
S. Fekete, J.-L. Veuthey, S. Eeltink, D. Guillarme, Comparative study of recent wide-pore materials of different stationary phase morphology, applied for the reversed-phase analysis of recombinant monoclonal antibodies, Anal Bioanal Chemistry, 405, 3137-3151 (2013).
M. Rodriguez-Aller, R. Gurny, J.-L. Veuthey, D. Guillarme, Coupling ultra high-pressure liquid chromatography with mass spectrometry: Constraints and possible applications, J. Chromatogr. A, 1292, 2-18 (2013).
Ch. Gourmel, A. Grand-Guillaume-Perrenoud, L. Waller, E. Reginato, J. Verne, B. Dulery, J.-L. Veuthey, S. Rudaz, J. Schappler, D. Guillarme, Evaluation and comparison of various separation techniques for the analysis of closely-related compounds of pharmaceutical interest, J. Chromatogr. A, 1282, 172-177 (2013).
K. Vuignier, D. Guillarme, J.-L. Veuthey, P-A. Carrupt, J. Schappler, High performance affinity chromatography (HPAC) as a high-throughouput screening tool in drug discovery to study drug-plasma protein interactions, Journal of Pharmaceutical and Biomedical Analysis, 74, 205-212 (2013).
I. Kohler, J. Schappler, T. Sierro, S. Rudaz, Dispersive liquid-liquid microextraction combined with capillary electrophoresis and time-of-flight mass spectrometry for urine analysis, Journal of Pharmaceutical and Biomedical Analysis, 73, 82-89 (2013).
S. Fekete, A.-L. Gassner, S. Rudaz, J. Schappler, D. Guillarme, Analytical strategies for the characterisation of therapeutic monoclonal antibodies, Trends in Analytical Chemistry, 42, 74-83 (2013).
I. Kohler, J. Schappler, S. Rudaz, Microextraction techniques combined with capillary electrophoresis in bioanalysis, Anal Bioanal Chem, 405, 125-141 (2013).
A. Periat, B. Debrus, S. Rudaz, D. Guillarme, Screening of the most relevant parameters for method development in ultra-high performance hydrophilic interaction chromatography, J. Chromatogr. A, 1282, 72-83 (2013).
S. Coutu, L. Rossi, D.A. Barry, S. Rudaz, N. Vernaz, Temporal Variability of Antibiotics Fluxes in Wastewater and Contribution from Hospitals, Plos One, 8, e53593 (2013).
G. Marti, M. Erb, J. Boccard, G. Glauser, G. Doyen, N. Villard, C. Robert, T. Turlings, S. Rudaz, J.-L. Wolfender, Metabolomics reveals herbivore-induced metabolites of resistance and susceptibility in maize leaves and roots, Plant, Cell & Environment, 36, 621-639 (2013).
J.-L. Wolfender, S. Rudaz, Y.H. Choi, H.K. Kim, Plant Metabolomics: From Holistic Data to Relevant Biomarkers, Current Medicinal Chemistry, 20, 1056-1090 (2013).
I. Constantin, G. Zelger, A. Paroz, P. Furrer, S. Rudaz, C. Messeiller, Development of Misoprostol Suppositories for Postpartum Hemorrhage, Pharmacology & Pharmacy, 4, 71-76 (2013).
J. Broseus, B. Debrus, O. Delemont, S. Rudaz, P. Esseiva, Study of common database feeding with results coming from different analytical methods in the framework of illicit drugs chemical profiling, Forensic Science International, 0, 0 (2013).
S. Fekete, K. Ganzler, D. Guillarme, Critical evaluation of fast size exclusion chromatographic separations of protein aggregates, applying sub-2 m particles, Journal of Pharmaceutical and Biomedical Analysis, 78-79, 141-149 (2013).
I. Kohler, J. Schappler, S. Rudaz, Highly sensitive capillary electrophoresis-mass spectrometry for rapid screening and accurate quantitation of drugs of abuse in urine, Analytica Chimica Acta, 780, 101-109 (2013).
M. Rodriguez-Aller, R. Gurny, J.-L. Veuthey, D. Guillarme, Coupling ultra high-presszre liquid chromatography with mass spectrometry: Constraints and possible applications, J. Chromatogr. A, 1292, 2-18 (2013).
B. Debrus, D. Guillarme, S. Rudaz, Improved quality-by-design compliant methodology for method development in reversed-phase liquid chromatography, Journal of Pharmaceutical and Biomedical Analysis, 84, 215-223 (2013).
S. Fekete, M. W. Dong, T. Zhang, D. Guillarme, High resolution reversed ohase analysis of recombinant monoclonal antibodies by ultra-high pressure liquid chromatography column coupling, Journal of Pharmaceutical and Biomedical Analysis, 83, 273-278 (2013).
D. Guillarme, M.W. Dong, Newer developments in HPLC impacting pharmaceutical analysis: a brief review, American Pharma. Rev., 16 (4), 36-43 (2013).
B. Debrus, P. Lebrun. E. Rozet, T. Schofield, R.D. Marini, S. Rudaz, B. Boulanger, Ph. Hubert, A New method for Quality-by-Design Robust Optimizations in Liquid Chromatography, LC-GC Europe , 26, 370-377 (2013).
F. Mehl, G. Marti, J. Boccard, B. Debrus, P. Merle, E. Delort, L. Baroux, V. Raymo, M.I. Velazco, H. Sommerm J.-L. Wolfender, S. Rudaz, Differentiation of lemon essential oil based on volatile and non-volatile fractions with various analytical techniques: a metabolomic approach, Food Chemistry, 143, 325-335 (2013).
A. Periat, A. Grand-Guillaume-Perrenoud, D. Guillarme, Evaluation of various chromatographix approaches for the retention of hydrophilic compounds and MS compatibility, J. Sep. Sci., 36, 3141-3151 (2013).
S. Fekete, D. Guillarme, Possibilities of new generation columns packed with 1.3um core-shedd particles in gradient elution mode, J. Chromatogr A, 1320, 86-96 (2013).
S. Fekete, D. Guillarme, Kinetic evaluation of new generation of column packed with 1.3 um, J. Chromatogr. A, 1308, 104-113 (2013).
A. Carl Sanchez, G. Friedlander, S. Fekete, J. Anspach, D. Guillarme, M. Chitty, T. Farkas, Pushing the performance limits of reversed-phase ultra highperformance liquid chromatography with 1.3 um core shell particles, J. Chromatogr. A, 1311, 90-97 (2013).
S. Fekete, K. Horvath, D. Guillarme, Influence of pressure and temperature on molar volume and retention, J. Chromatogr. A, 1311, 65-71 (2013).
A.-L. Gassner, S. Rudaz, J. Schappler, Static coating for the analysis of intact monoclonal antibody drugs by capillary zone electrophoresis, Electrophoresis, 34, 2718-2724 (2013).
A. Periat, A. Grand-Guillaume-Perrenoud, D. Guillarme, Evaluation of various chromatographix approaches for the retention of hydrophilic compounds and MS compatibility, Journal of Separation Science, 36, 3141-3151 (2013).
N. Marsousi, V. Ancrenaz, Y. Daali, S. Rudaz, C. Samer, J. Desmeules, Influence of genetic polymorphisms on the response variability to opioids, Food Chemistry, 26, 203-208 (2013).

S. Fekete, J.-L. Veuthey, D.V. McCallex, D. Guillarme, The effect of pressure and mobile phase velocity on the retention properties of small analytes and large biomolecules in ultra-high-pressure liquid chromatography, J. Chromatogr. A, 1270, 127-138 (2012).
S. Fekete, S. Rudaz, J.-L. Veuthey, D. Guillarme, Impact of mobile phase temperature on recovery and stability of monoclonal antibodies using recent reversed phase stationary phases, Journal of Separation Science, 35, 3113-3123 (2012).
A. Grand-Guillaume-Perrenoud, J.-L. Veuthey, D. Guillarme, Comparison of ultra-high performance supercritical fluid chromatography and ultra-high performace liquid chromatography for the analysis of pharmaceutical compounds, J. Chromatogr. A, 1266, 158-167 (2012).
S. Herzig, E. Raemy, S. Montessuit, J.-L. Veuthey, N. Zamboni, B. Westermann, E. R. S. Kunji, J.-C. Martinou, Identification and Functional Expression of the Mitochondrial Pyruvate Carrier, Science, 337, 93-96 et 1-10 (2012).
A. Grand-Guillaume-Perrenoud, J. Boccard, J.-L. Veuthey, D. Guillarme. , Analysis of basic compounds by supercritical fluid chromatography: Attemps to improve peak shape and maintain mass spectrometry compatibility, J. Chromatogr. A, 1262, 205-213 (2012).
S. Fekete, J.-L. Veuthey, D. Guillarme, New trends in reversed-phase liquid chromatographic separation of therapeutique peptides and proteins: Theory and applications., Journal of Pharmaceutical and Biomedical Analysis, 69, 9-27 (2012).
S. Fekete, R. Berky, J. Fekete, J.-L. Veuthey, D. Guillarme, Evaluation of recent very efficient wide-pore stationary phases for the reversed-phase separation of proteins, J. Chromatogr. A, 1252, 90-103 (2012).
K. Vuignier, J.-L. Veuthey, P.-A. Carrupt, J. Schappler, Characterization og drug-protein interaction by capillary electrophoresis hyphenated to mass spectrometry, Electrophores, 33, 1-10 (2012).
D. Guillarme, J. Schappler, J. Boccard, J.-L. Veuthey, S. Rudaz, New insights in pharmaceutical analysis, Chimia, 66, 330-334 (2012).
S. Fekete, R. Berky, J. Fekete, J.-L. Veuthey, D. Guillarme, Evaluation of a new wide pore core-shell material (Aeris TM WIDEPORE) and comparison with other existing stationary phases for the analysis of intact proteins, J. Chromatogr. A, 1236, 177-188 (2012).
J. Boccard, F. Badoud, E. Grata, S. Ouertani. M. Hanafi, G. Mazerolles, P. Lantéri, J.-L. Veuthey, S. Rudaz, Analyse métabolomique dans l’urine par UHPLC-QTOF-MSE: profilage des steroids appliqué au dépistage antidopage, Spectra Analyse, 284, 48-54 (2012).
G. Bonvin, J.-L. Veuthey, S. Rudaz, J. Schappler, Evaluation of a sheathless nanospray interface based on a porous tip sprayer for CE-ESI-MS coupling, Electrophoresis, 33, 552-562 (2012).
S. Nussbaumer, L. Geiser, F. Sadeghipour, D. Hochstrasser, P. Bonnabry, J.-L. Veuthey, S. Fleury-Souverain, Wipe sampling procedure coupled to LC-MS/MS analysis for the simultaneous determination of 10 cytotoxic drugs on different surfaces, Anal Bioanal Chemistry, 402, 2499-2509 (2012).
J. Ruta, J. Boccard, D. Cabooter, S. Rudaz, G. Desmet, J.-L. Veuthey, D. Guillarme, Method development for pharmaceutics: some solutions for tuning selectivity in reversed phase and hydrophilic interaction liquid chromatography, Journal of Pharmaceutical and Biomedical Analysis, 63, 95-105 (2012).
M. Rodriguez-Aller, B. Kaufmann, D. Guillarme, C. Stella, P. Furrer, S. Rudaz, I. El Zaoui, F. Valamanesh, C. Di Tommaso, F. Behar-Cohen, J.-L. Veuthey, R. Gurny, In vivo characterrisation of a novel water-soluble Cyclosporine A prodrug for the treatment of dry eye disease, Eur. journal of Pharm. and Biopharm., 80, 544-552 (2012).
J.Ruta, D. Zurlino, C. Grivel, S. Heinisch, J.-L. Veuthey, D. Guillarme, Evaluation of columns packed with shell particles with compounds of pharmaceutical interest, J. Chromatogr. A, 1228, 221-231 (2012).
S. Fekete, R. Berky, J. Fekete, J.-L. Veuthey, D. Guillarme, Evaluation of recent very efficient wide-pore stationary phases for the reversed-phase separation of proteins, J. Chromatogr. A, 152, 90-103 (2012).
S. Fekete, S. Rudaz, J. Fekete, D. Guillarme, Analysis of recombinant monoclonal antibodies by RPLC: Toward a generic method development approach, Journal of Pharmaceutical and Biomedical Analysis, 70, 158-168 (2012).
E. Tyteca, A. Liekens, D. Clicq, A. Fanigliulo, B. Debrus, S. Rudaz, D. Guillarme, A. Desmet, Predictive Elution Window Stretching and Shifting as a Generic Search Strategy for Automated Method Development for Liquid Chromatography, Analytical Chemistry, 84, 7823-7830 (2012).
Ph. J. Eugster, D. Biass, D. Guillarme, Ph. Favreau, R. Stöcklin, J.-L. Wolfender, Peak capacity optimisation for high resolution peptide profiling in complex mixtures by liquid chromatography coupled to time-of-flight mass spectrometry: Application to the Conus consors cone snail venom, J. Chromatogr. A, 1259, 187-199 (2012).
G. Bonvin, J. Schappler, S. Rudaz, Capillary electrophoresis-electrospray ionization-mass spectrometry interfaces: Fundamental concepts and technical developments, J. Chromatogr A, 1267, 17-31 (2012).

G. Mazerolles, J. Boccard, M. Hanafi, S. Rudaz, Analysis of experimental design with multivariate response: A contribution using multiblock techniques , Chem. Intel. Lab. Systems, 106, 65-72 (2011).
E. Rozet, R.D. Marini, E. Ziemons, W. Dewe, S. Rudaz, B. Boulanger, Ph. Hubert, Total error and uncertainty: Friends or foes?, TrAC, 30, 797-806 (2011).
E. Rozet, S. Rudaz, R.D. Marini, E. Ziémons, B. Boulanger, Ph. Hubert, Models to estimate overall analytical measurements uncertainty: Assumptions, comparisons and applications, Analytica Chimica Acta, 702, 160–171 (2011).
S. Fekete, S. Rudaz, J.-L. Veuthey, D. Guillarme, Impact of mobile phase temperature on recovery and stability of monoclonal antibodies using recent reversed phase stationary phases, Journal of Separation Science, 35, 3113-3123 (2011).
A. Staub, D. Zurlino, S. Rudaz, J.-L. Veuthey, D. Guillarme, Analysis of peptides and proteins using sub-2 µm fully porous and sub 3-µm shell particles, J. Chromatogr. A, 1218, 8903-8914 (2011).
J. Boccard, F. Badoud, E. Grata, S. Ouertani, M. Hanafi, G. Mazerolles, P. Lantéri, J.-L. Veuthey, M. Saugy, S. Rudaz, A steroidomic approach for biomarkers discovery in doping control, Forensic Science International, 213, 85-94 (2011).
J. Schappler, A. Staub, S. Rudaz, J.-L. Veuthey, Nouveaux développements dans l'analyse de protéines intactes par CE-TOF/MS, Spectra Analysis, 281, 24-30 (2011).
F. Badoud, D. Guillarme, J. Boccard, E. Grata, M. Saugy, S. Rudaz, J.-L. Veuthey, Analytical aspects in doping control: Challenges and perspectives, Forensic Science International, 213, 49-61 (2011).
F. Badoud, D. Guillarme, J. Boccard, E. Grata, M. Saugy, S. Rudaz, J.-L. Veuthey, Analytical aspects in doping control: challenges and perspectives, Forensic science international, 213, 49-61 (2011).
M. Rovini, J. Schappler, I. Kohler, M. Anzini, J.-L. Veuthey, S. Rudaz, Sample Preparation of Urine Samples Prior to CE-MS in Toxicological Analysis, J. Chem. Chem. Eng., 5, 583-594 (2011).
L. Nováková, J.-L. Veuthey, D. Guillarme, Practical method transfer from high performance liquid chromatography to ultra-high performance liquid chromatography: The importance of frictional heating, J. Chromatogr. A, 1218, 7971-7981 (2011).
S. Fleury-Souverain, S. Nussbaumer, J. Schappler, P. Bonnabry, J.-L. Veuthey, Interest of capillary electrophoresis for the quality control of pharmaceutical formulations produced in hospital pharmacy, EJHPPractice, 17, 32-34 (2011).
S. Nussbaumer, P. Bonnabry, J.-L. Veuthey, S. Fleury-Souverain, Analysis of anticancer drugs: A review, Talanta, 85, 2265-2289 (2011).
V. Viette, M. Fathi, S. Rudaz, D. Hochstrasser, J.-L. Veuthey, Current tole of LC-MS intoxicological screening methods, J. Clin. Chem. And Lab. Med. , 49 (7), 1091-1103 (2011).
I. Kohler, E. Cognard, I. Marchi, D. Ortelli, P. Edder, J.-L. Veuthey, S. Rudaz, J. Schappler, Single-Run Separation of Closely Related Cationic and Anionic Compounds by CE-ESI-MS: Application to the Simultaneous Analysis of Melamine and its Analogs in Milk. , Chimia, 65, 389-395 (2011).
S. Fleury, S. Nussbaumer, J. Schappler, P. Bonnabry, J.-L. Veuthey, Interest of capillary electrophoresis for the quality control of pharmaceutical formulations produced in hospital pharmacy, EJHP Practice, 17, 1-3 (2011).
E. Choong, S. Rudaz, A. Kottelat, S. Haldemann, D. Guillarme, J.-L. Veuthey, C. Eap, Quantification of 4 antidepressants and a metabolite by LC-MS for therapeutic drug monitoring, J. Chromatogr. B, 879, 1544-1550 (2011).
A. Staub, D. Guillarme, J. Schappler, J.-L. Veuthey, S. Rudaz, Intact protein analysis in the biopharmaceutical field, Journal of Pharmaceutical and Biomedical Analysis, 55, 810-822 (2011).
F. Badoud, E. Grata, J. Boccard, D. Guillarme, J.-L. Veuthey, S. Rudaz, M. Saugy, Quantification of glucuronidated and sulphated steroids in human urine by ultra-high pressure liquid chromatography quadrupole time-of-flight mass spectrometry, Anal Bioanal Chem., 400, 503-516 (2011).
S. Nussbaumer, S. Fleury-Souverain, J. Schappler, S. Rudaz, J.-L. Veuthey, P. Bonnabry, Quality control of pharmaceutical formulations containing cisplatin, corboplatin, and oxaliplatin by micellar and microemulsion electrokinetic chromatography (MEKC, MEEKC), Journal of Pharmaceutical and Biomedical Analysis, 55, 253-258 (2011).
B. Debrus, J. Broséus, D. Guillarme, P. Lebrun, P. Hubert, J.-L. Veuthey, P. Esseiva, S. Rudaz, Innovative methodology to transfer conventional GC-MS herion profiling to UHPLC-MS/MS, Anal. Bioanal. Chem., 399, 2719-2730 (2011).
Ph. J. Eugster, D. Guillarme, S. Rudaz, J.-L. Veuthey, P.-A. Carrupt, J.-L. Wolfender, Ultra High Pressure Liquid Chromatography for Crude Plant Extract Profiling, Journ. of AOAC Intern., 94/1, 51-70 (2011).
V. Viette, D. Guillarme, R. Mylonas, Y. Mauron, M. Fathi, S. Rudaz, D. Hochstrasser, J.-L. Veuthey, A multi-target screening analysis in human plasma using fast liquid chromatography-hybrid tandem mass spectrometry (Part II), Clinical Biochemistry, 44, 45-53 (2011).
V. Viette, D. Guillarme, R. Mylonas, Y. Mauron, M. Fathi, S. Rudaz, D. Hochstrasser, J.-L. Veuthey, A multi-target screening analysis in human plasma using fast liquid chromatography-hybrid tandem mass spectrometry (Part I), Clinical Biochemistry, 44, 34-44 (2011).

J. Ruta, S. Rudaz, D. V. McCalley, J.-L. Veuthey, D. Guillarme, A systematic investigation of the effect of sample diluent on peak shape in hydrophilic interaction liquid chromatography, J. Chromatogr. A, 1217, 8230-8240 (2010).
S. Nussbaumer, S. Fleury-Souverain, P. Antinori, F. Sadeghipour, D. F. Hochstrasser, P. Bonnabry, J.-L. Veuthey, L. Geiser, Simultaneous quantification of ten cytotoxic drugs by a validated LC-ESI-MS/MS method, Anal. Bioanal. Chem., 398, 3033-3042 (2010).
A. Staub, S. Rudaz, J.-L. Veuthey, J. Schappler, Multiple injection technique for the determination and quantitation of insulin formulations by capillary electrophoresis and time-of-flight mass spectrometry, J. Chromatogr. A, 1217, 8041-8047 (2010).
R. Curcio, R. Nicoli, S. Rudaz, J.-L. Veuthey, Evaluation of an in-capillary approach for performing quantitative cytochrome P450 activity studies, Anal. Bioanal. Chem., 398, 2163-2171 (2010).
D. Guillarme, C. Casetta, C. Bicchi, J.-L. Veuthey, High throughput qualitative analysis of polyphenols in tea samples by ultra-high pressure liquid chromatography coupled to UV and mass spectrometry detectors, J. Chromatogr. A, 1217, 6882-6890 (2010).
A. Staub, S. Comte, S. Rudaz, J.-L. Veuthey, J. Schappler, Use of organic solvent to prevent protein adsorption in CE-MS experiments, Electrophor., 31, 3326-3333 (2010).
K. Vuignier, J. Schappler, J.-L. Veuthey, P.-A. Carrupt, S. Martel, Drug-protein binding : a critical review of analytical tools, Anal. Bioanal. Chem., 398, 53-66 (2010).
R. D. Marini, E. Rozet, M.-L. Aja Montes, S. Roth, C. Rohrbasser, D. Rhème, P. Bonnabry, J. Schappler, J.-L. Veuthey, Ph. Hubert, S. Rudaz, Reliable low cost capillary electrophoresis device for drug quality control and counterfeit medicines, Journal of Pharmaceutical and Biomedical Analysis, 53, 1278-1287 (2010).
K. Vuignier, J. Schappler, J.-L. Veuthey, P.-A. Carrupt, S. Martel, Improvement of a capillary electrophoresis/frontal analysis (CE/FA) method for determining binding constants: discussion on relevant parameters, Journal of Pharmaceutical and Biomedical Analysis, 53, 1288-1297 (2010).
J. Ruta, D. Guillarme, S. Rudaz, J.-L. Veuthey, Comparison of columns packed with porous sub-2µm particles and superficially porous sub-3µm particles for peptides analysis at ambient and high temperature, J. Sep. Sci., 33, 2465-2477 (2010).
S. Nussbaumer, S. Fleury-Souverain, L. Bouchoud, S. Rudaz, P. Bonnabry, J.-L. Veuthey, Determination of potassium, sodium, calcium and magnesium in total parental nutrition formulations by capillary electrophoresis with contactless conductivity detection, Journal of Pharmaceutical and Biomedical Analysis, 53, 130-136 (2010).
D. Guillarme, J. Ruta, S. Rudaz, J.-L. Veuthey, New trends in fast and high-resolution liquid chromatography: a critical comparison of existing approaches, Anal. Bioanal Chem., 397, 1069-1082 (2010).
F. Badoud, E. Grata, L. Perrenoud, M. Saugy, S. Rudaz, J.-L. Veuthey, Fast analysis of doping agent in urine by ultra-high-pressure liquid chromatography-quadrupole time-of-flight mass spectrometry. II : Confirmatory analysis, J. Chromatogr. A, 1217, 4109-4119 (2010).
I. Marchi, V. Viette, F. Badoud, M. Fathi, M. Saugy, S. Rudaz, J.-L. Veuthey, Characterization and classification of matrix effects in biological samples analyses, J. Chromatogr. A, 1217, 4071-4078 (2010).
R. Nicoli, S. Martel, S. Rudaz, J.-L. Wolfender, J.-L. Veuthey, P.-A. Carrupt, D. Guillarme, Advances in LC platforms for drug discovery, Expert Opin. Drug Discov., 5, 475-489 (2010).
B. Chauve, D. Guillarme, P. Cléon, J.-L. Veuthey, Evaluation of various HILIC materials for the fast separation of polar compounds, J. Sep. Sci., 33, 752-764 (2010).
A. Staub, S. Rudaz, M. Saugy, J.-L. Veuthey, J. Schappler, Analysis of hemoglobin-based oxygen carriers by CE-UV/Vis and CE-ESI-TOF/MS, Electrophor., 31, 1241-1247 (2010).
Y. Henchoz, S. Romand, J. Schappler, S. Rudaz, J.-L. Veuthey, P.-A. Carrupt, High-throughput log P determination by MEEKC coupled with UV and MS detections, Electrophor., 31, 952-964 (2010).
J. Boccard, J.-L. Veuthey, S. Rudaz, Knowledge discovery in metabolomics: an overview of MS data handling, J. Sep. Sci., 33, 290-304 (2010).
A. Staub, S. Giraud, M. Saugy, S. Rudaz, J.-L. Veuthey, J. Schappler, CE-ESI-TOF/MS for human growth hormone analysis, Electrophor., 31, 388-395 (2010).
D. Guillarme, G. Bonvin, F. Badoud, J. Schappler, S. Rudaz, J.-L. Veuthey, Fast chiral separation of drugs using columns packed with sub-2 µm particles and ultra-high pressure, Chirality, 22, 320-330 (2010).
D. Guillarme, J. Schappler, S. Rudaz, J.-L. Veuthey, Coupling ultra-high-pressure liquid chromatography with mass spectrometry, Trends in Analytical Chemistry, 29, 15-27 (2010).
C. Grivel, J.-L. Rocca, D. Guillarme, J.-L. Veuthey, S. Heinisch, Selection of suitable operating conditions to minimize the gradient equilibration time in the separation of drugs by Ultra-HighPressure Liquid Chromatography with volatile (mass spectrometry-compatible) buffers, J. Chromatogr. A, 1217, 459-472 (2010).
J.-L. Veuthey, Forensic and toxicological analysis, Anal Bioanal Chem, 396, 2377-2378 (2010).
D. Guillarme, S. Heinisch, Utilisation de très hautes températures en chromatographie en phase liquide: possibilités et limites., Spectra Anal. , 274, 28-34 (2010).
R.D. Marini, J. Mbinze Kindenge, M.L.. Montes, B. Debrus, P. Lubrun, J. Mantanus, E. Ziemind, C. Rohrbasser, S. Rudaz, Ph. Hubert, Analytical tools to fight against counterfeit medecines. Chemistry today , Focus on pharm. anal., 28, 10-14 (2010).
G. Glauser, J. Boccard, S. Rudaz, J.-L. Wolfender, Mass spectrometry-based metabolomics oriented by correlation analysis for wound-induced modecule discovery: identification of a novel jasmonate glucoside, Phytochem. Anal., 21, 95-101 (2010).
J. Boccard, A. Kalousis, M. Hilario, P. Lantéri, M. Hanafi, G. Mazerolles, J.-L. Wolfender, P.-A. Carrupt, S. Rudaz, Standard machine learning algorithms applied to UPLC-TOF/MS metabolic fingerprinting for the discovery of wound biomarkers in Arabidopsis thaliana, Chem. Intel. Lab. Syst., 104, 20-27 (2010).

C. Rohrbasser, D. Rhême, S. Décastel, S. Roth, M.A. Montes, J.-L. Veuthey, S. Rudaz, A new capillary electrophoresis device with deep UV detector based on LED technology, Chimia, 63, 890-891 (2009).
A. Maquille, D. Guillarme, S. Rudaz, J.-L. Veuthey, High-throughput screening of drugs of abuse in urine by supported liquid-liquid extraction and ultra high pressure liquid chrimatigraphy coupled to tandem mass spectrometry, Chromatographia, 70, 1373-1780 (2009).
S. Schindhelm, A. Weber, C. Andrés-Barrao, C. Schelling, A.M. Stchigel, J. Cano, J.-L. Veuthey, J. Bourgeois, F. Barja, Biochemical and morphological characterization of a new fungal contaminant in balsamic and cider vinegars, Food Addit. Contam., 26:9, 1306-1313 (2009).
A. Guillot, Y. Henchoz, C. Moccand, D. Guillarme, J.-L. Veuthey, P.-A. Carrupt, S. Martel, Lipophilicity determination of highly lipophilic compounds by liquid chromatography, Chemistry and biodiversity , 6, 1828-1836 (2009).
E. Choong, S. Rudaz, A. Kottelat, D. Guillarme, J.-L. Veuthey, C. B. Eap, Therapeutic drug monitoring of seven psychotropic drugs and four metabolites in human plasma by HPCL-MS, J. Pharm. Biomed. Anal., 50, 1000-1008 (2009).
Y. Henchoz, D. Guillarme, S. Martel, S. Rudaz, J.-L. Veuthey, P.-A. Carrupt, Fast log P determination by ultra-high-pressure liquid chromatography coupled with UV and mass spectrometry detections, Anal. Bioanal. Chem., 394, 1919-1930 (2009).
N. Ansermot, S. Rudaz, M. Brawand-Amey, S. Fleury-Souverain, J.-L. Veuthey, C. B. Eap, Validation and long-term evaluation of a modified on-line chiral analaytical method for therapeutic drug monitoring of (R,S)-methadone in clinical samples, J. Chromatogr. B, 877, 2301-2307 (2009).
I. Marchi, J. Schappler, J.-L. Veuthey, S. Rudaz, Development and validation of a liquid chromatography-atmospheric pressure photoionization-mass spectrometry method for the quantification of alprazolam, flunitrazepam, and their main metabolites in haemolysed blood, J. Chromatogr. B, 877, 2275-2283 (2009).
E. Grata, D. Guillarme, G. Glauser, J. Boccard, P.-A. Carrupt, J.-L. Veuthey, S. Rudaz, J.-L. Wolfender, Metabolite Profiling of Plant Extracts by Ultra-high-pressure Liquid Chromatography at Elevated Temperature Coupled to Time-of-flight Mass Spectrometry, J. Chromatogr. A, 1216, 5660-5668 (2009).
Y. Henchoz, N. Abla, J.-L. Veuthey, P.-A. Carrupt, A Fast Screening Strategy for Characterizing Peptide Delivery by Transdermal Iontophoresis, J. Controlled Release, 137, 123-129 (2009).
A. Staub, J. Schappler, S. Rudaz, J.-L. Veuthey, CE-TOF/MS: Fundamental concepts, instrumental considerations and applications, Electrophor., 30, 1610-1923 (2009).
D. Guillarme, E. Grata, G. Glauser, J.-L. Wolfender, J.-L. Veuthey, S. Rudaz, Some Solutions to Obtain Very Efficient Separations in Isocratic and Gradient Modes Using Small Particles Size and Ultra-high Pressure, J. Chromatogr. A, 1216, 3232-3243 (2009).
D. Guillarme, S. Rudaz, J.-L. Veuthey, Nouveaux développements en chromatographie rapide dans le domaine pharmaceutique, Spectra Anal., 267, 12-17 (2009).
Y. Henchoz, B. Barde, D. Guillarme, P.-A. Carrupt, J.-L. Veuthey. S. Martel, Analytical tools for the physicochemical profiling of drug candidates to predict absorption/distribution, Anal. Bioanal. Chem., 394, 707-729 (2009).
F. Badoud., E Grata., L Perrenoud., L Avois., M Saugy. S, Rudaz., J.-L Veuthey, Fast Analysis of Doping Agents in Urine by Ultra-high Pressure Liquid Chromatography-Quadrupole Time-of-Flight Mass Spectrometry – Part I: Screening Analysis, J. Chromatogr. A, 1216, 4423-4433 (2009).
R. Nicoli, R. Curcio, S. Rudaz, J.-L. Veuthey, Development of an In-Capillary Approach to Nanoscale Automated in Vitro Cytochromes P450 Assays, J. Med. Chem., 52 (8), 2192-2195 (2009).
K. R. Ing-Lorenzini, J. A. Desmeules, M. Besson, J.-L. Veuthey, P. Dayer, Y. Daali, Two-dimensional Liquid Chromatography-ion Trap Mass Spectrometry for the Simultaneous Determination of Detorolac Enantiomers and Paracetamol in Human plasma. Application to a Pharmacokinetic Study, J. Chromatogr. A, 1216, 3851-3856 (2009).
A. Sieg, F. Jeanneret, M. Fathi, D. Hochstrasser, S. Rudaz, J.-L. Veuthey, R. H. Guy, M. Begoña Delgado-Charro, Extraction of Amino Acids by Reverse Iontophoresis in vivo, Eur. J. Pharm. Biopharm., 72, 226-231 (2009).
R. Nicoli, S. Rudaz, C. Stella, J.-L. Veuthey, Trypsin immobilisation on an ethylenediamine-based monolithic minidisk for rapid on-line peptide mass fingerprinting studies, J. Chromatogr. A, 1216, 2695-2699 (2009).
J. Schappler, R. Nicoli, D. Nguyen, S. Rudaz, J.-L. Veuthey, D. Guillarme, Coupling Ultra High-Pressure Liquid Chromatography with Single Quadrupole Mass Spectrometry for the Analysis of a Complex Drug Mixture, Talanta, 78, 377-387 (2009).
I. Marchi, S. Rudaz, J.-L. Veuthey, Sample Preparation Development and Matrix Effects Evaluation for Multianalyte Determination in Urine, J. Pharm. Biomed. Anal., 49, 459-467 (2009).
S. Nussbaumer, S. Fleury-Souverain, S. Rudaz, P. Bonnabry, J.-L. Veuthey, Determination of Suxamethonium in a Pharmaceutical Formulation by Capillary Electrophoresis with Contactless Conductivity Detection (CE-C4D), J. Pharm. Biomed. Anal., 49, 333-337 (2009).
I. Marchi, S. Rudaz, J.-L. Veuthey, Atmospheric Pressure Photoionization for Coupling Liquid-chromatography to Mass Spectrometry : A Review, Talanta, 78, 1-18 (2009).
L. Geiser, J.-L. Veuthey, Non-aqueous Capillary Electrophoresis 2005-2008, Electrophor., 30, 36-49 (2009).
G. Glauser, K. Gindro, J. Fringeli, J.-P. De Joffrey, S. Rudaz, J.-L. Wolfender, Differential Analysis of Mycoalexins in Confrontation Zones of Grapevine Fungal Pathogens by Ultrahigh Pressure Liquid Chromatography/Time-of-Flight Mass Spectrometry and Capillary Nuclear Magnetic Resonance, J. Agri. Food Chem., 57, 1127-1134 (2009).
J. Boccard, F. Bajot, A. Di Pietro, S. Rudaz, A. Boumendjel, E. Nicolle, P.-A. Carrupt, A 3D linear solvation energy model to quantify the affinity of flavonoid derivatives toward P-glycoprotein, Eur. J. Pharm.Sci., 36, 254-264 (2009).
S. Rudaz, Ph. Hubert, Method validation, comparison and transfer, J. Chromatogr. B , 877, 2179 (2009).
B. Boulanger, E. Rozet, F. Moonen, S. Rudaz, Ph. Hubert, A risk-based analysis of the AAPS conference report on quantitative bioanalytical methods validation and implementation, J. Chromatogr. B , 877, 2179 (2009).
J.-L. Wolfender, G. Glauser, J. Boccard, S. Rudaz, MS-based Plant Metabolomic Approaches for Biomarker Discovery , Natural Product Discovery , 4, 1417-1430 (2009).
G. Glauser, L. Dubugnon, S. A. R. Mousavi, S. Rudaz, J.-L. Wolfender, E.E. Farmer , Velocity Estimates for Signal Propagation Leading to Systemic Jasmonic Acid Accumulation in Wounded Arabidopsis , J. Biol. Chem, 284, 34506-34513 (2009).

D. Guillarme, J.-L. Veuthey, Description d’une Méthode d’Evaluation et de Comparaison, LC-CG en français, décembre 2008, 18-24 (2008).
D. Guillarme, C. Schelling, S. Rudaz, J.-L. Veuthey, Ultra-Fast Separation of Pharmaceutical Compounds with 10mm Columns Packed with Sub-2mm Particles, LC-GC, 21, 488-501 (2008).
A. Sieg, F. Jeanneret, M. Fathi, D. Hochstrasser, S. Rudaz, J.-L. Veuthey, R. H. Guy, M. B. Delgado-Charro, Extraction of Amino Acids by Reverse Iontophoresis: Simulation of Therapeutic Monitoring in Vitro, Eur. J. Pharm. Biopharm., 70, 908-913 (2008).
R. Nicoli, M. Bartolini, S. Rudaz, V. Andrisano, J.-L. Veuthey, Development of Immobilized Enzyme Reactors Based on Human Recombinant Cytochrome P450 Enzymes for Phase I Drug Metabolism Studies, J. Chromatogr. A, 1206, 2-10 (2008).
R. Nicoli, N. Gaud, C. Stella, S. Rudaz, J.-L. Veuthey, Trypsin Immobilization on Three Monolithic Disks for On-line Protein Digestion, J. Pharm. Biomed. Anal., 48, 398-407 (2008).
J. Schappler, A. Staub, J.-L. Veuthey, S. Rudaz, Highly Sensitive Detection of Pharmaceutical Compounds in Biological Fluids Using Capillary Electrophoresis Coupled with Laser-induced Native Fluorescence, J. Chromatogr. A, 1204, 183-190 (2008).
R. Russo, D. Guillarme, C. Bicchi, S. Rudaz, J.L. Veuthey, Evaluation of the coupling between ultra performance liquid chromatography and evaporative light scattering detector for selected phytochemical applications, J. Sep. Sci., 31, 2377-2387 (2008).
N. Ansermot, M. Fathi, J.-L. Veuthey, J. Desmeules, S. Rudaz, D. Hochstrasser, Quantification of Cyclosporine and Tacrolimus in Whole Blood. Comparison of Liquid Chromatography-electrospray Mass Spectrometry with the Enzyme Multiplied Immunoassay Technique, Clin. Biochem., 41, 910-913 (2008).
D. Guillarme, V. Meyer, J.L. Veuthey, Method transfer in HPLC, LC-GC Europe, 21, 322-327 (2008).
E. Strahm, I. Kohler, S. Rudaz, S. Martel, P.-A. Carrupt, J.-L. Veuthey, M. Saugy, C. Saudan, Isolation and Quantification by High-performance Liquid Chromatography-ion-trap Mass Spectrometry of Androgen Sulfoconjugates in Human Urine, J. Chromatogr. A, 1196-1197, 153-160 (2008).
N. Ansermot, M. Fathi, J.-L. Veuthey, J. Desmeules, S. Rudaz, D. Hochstrasser, Simultaneous Quantification of Cyclosporine , Tacrolimus, Sirolimus and Everolimus in whole Blood by Liquid Chromatography-electrospray Mass Spectrometry, Clin. Biochem., 41, 728-735 (2008).
J. Schappler, D. Guillarme, J. Prat, J.-L. Veuthey, S. Rudaz, Validation of chiral CE-ESI/MS methods for ectasy and methadone in plasma, Electrophor., 29, 2193-2202 (2008).
L. Gremaud, J. Schappler, J.-L. Veuthey, C. Rohrbasser, S. Rudaz, Analysis of Amphetamine Derivatives in Plasma Using Capillary Zone Electrophoresis Coupled with Laser-Induced Fluorescence after Derivatization on Solid-Phase Extraction Support, Chimia, 62, 210-214 (2008).
R. Russo, D. Guillarme, D. Nguyen, C. Bicchi, S. Rudaz, J.L. Veuthey, Pharmaceutical applications on columns packed with sub-2µm particles, J. Chromatogr. Sci., 46, 199-208 (2008).
D. Guillarme, S. Rudaz, C. Schelling, M. Dreux, J.L. Veuthey, Micro liquid chromatography coupled with evaporative light scattering detector: modification of the nebulization cell geometry, J. Chromatogr. A, 1192, 103-112 (2008).
D. Nguyen, D. Guillarme, S. Rudaz, J.L. Veuthey, Validation of an ultra-fast UPLC-UV method for the separation of anti-tuberculosis tablets, J. Sep. Sci., 31, 1050-1056 (2008).
P. Rubiolo, E. Liberto, B. Sgorbini, R. Russo, J.-L. Veuthey, C. Bicchi, Fast-GC-conventional Quadrupole Mass Spectrometry in Essential Oil Analysis, J. Sep. Sci., 31, 1074-1084 (2008).
E. Strahm, S. Rudaz, J.-L. Veuthey, M. Saugy, C. Saudan, Profiling of 19-norsteroid sulfoconjugates in human urine by liquid chromatography mass spectrometry, Anal. Chim. Acta., 613, 228-237 (2008).
Y. Henchoz, D. Guillarme, S. Rudaz, J.L. Veuthey, P.A. Carrupt, Fast logP measurements by ultra performance liquid chromatography, a promising high throughput tool for medicinal chemists, J. Med. Chem., 51, 396-399 (2008).
G. Glauser, D. Guillarme, E. Grata, J. Boccard, A. Thiocone, P.A. Carrupt, J.L. Veuthey, S. Rudaz, J.L. Wolfender, Optimized liquid chromatography-mass spectrometry approach for the isolation of minor stress biomarkers in plant extracts and their identification by capillary nuclear magnetic resonance at the microgram scale, J. Chromatogr. A, 1180, 90-98 (2008).
D. Guillarme, D. Nguyen, S. Rudaz, J.L. Veuthey, Method transfer for fast liquid chromatography in pharmaceutical analysis: Application to short columns packed with small particles - Part II: Gradient Experiments, Eur. J. Pharm. Biopharm., 68, 430-440 (2008).
J. Schappler, D. Guillarme, J.-L. Veuthey, S. Rudaz, Microemulsion electrokinetic chromatography hyphenated to atmospheric pressure photoionization mass spectrometry (MEEKC-APPI-MS), Electrophor., 29, 11-19 (2008).
E. Grata, J. Boccard, D. Guillarme, G. Glauser, P.A. Carrupt, E.E. Farmer, J.L. Wolfender, S. Rudaz, UPLC-TOF-MS for plant metabolomics: a sequential approach for wound markers analysis in Arabidopsis Thaliana, J. Chromatogr. B, 871, 261-270 (2008).
G. Glauser, E. Grata, S. Rudaz, J.-L. Wolfender, High-resolution profiling of oxylipin-containing galactolipids in Arabidopsis extracts by ultraperformance liquid chromatography/time-of-flight mass spectrometry, Rapid Commun. Mass Spectrom., 22, 3154–3160 (2008).
G. Glauser, E. Grata, L. Dubugnon, S. Rudaz, E.E. Farmer, J.-L. Wolfender, Spatial and Temporal Dynamics of Jasmonate Synthesis and Accumulation in Arabidopsis in Response to Wounding, J. Bio. Chem., 283, 16400-16407 (2008).

Y. Henchoz, J. Schappler, L. Geiser, J. Prat, P.-A. Carrupt, J.-L. Veuthey, Rapid Determination of pKa Values of 20 Amino Acids by CZE with UV and Capacitively Coupled Contactless Conductivity Detections, Anal. Bioanal. Chem., 389, 1869-1878 (2007).
D. Guillarme, R. Russo, S. Rudaz, C. Bicchi, J.-L. Veuthey, Chromatographic Performance of Silica-Based Stationary Phases in High Temperature Liquid Chromatography : Pharmaceutical Applications, Curr. Pharm. Anal., 3, 221-229 (2007).
D. T.-T. Nguyen, D. Guillarme, S. Heinisch, M.-P. Barrioulet, J.-L. Rocca, S. Rudaz, J.-L. Veuthey, High throughput liquid chromatography with sub-2µm particles at high pressure and high temperature, J. Chromatogr. A, 1167, 76-84 (2007).
N. Ansermot, M. Fathi, J.-L. Veuthey, J. Desmeules, D. Hochstrasser, S. Rudaz, Quantification of cyclosporine A in peripheral blood mononuclear cells by liquid chromatography-electrospray mass spectrometry using a column-switching approach, J. Chromatogr. B, 857, 92-99 (2007).
J. Billen, D. Guillarme, S. Rudaz, J.-L. Veuthey, H. Ritchie, B. Grady, G. Desmet, Relation between the particle size distribution and the kinetic performance of packed columns. Application to a commercial sub-2 Âµm particle material, J. Chromatogr. A, 1161, 224-233 (2007).
J. Schappler, D. Guillarme, J. Prat, J.-L. Veuthey, S. Rudaz, Coupling CE with atmospheric pressure photoionization MS for pharmaceutical basic compounds: optimization of operating parameters, Electrophor., 28, 3078-3087 (2007).
I. Marchi, D. T.-T. Nguyen, D. Guillarme, L. Mateus-Avois, M. Saugy, S. Rudaz, J.-L. Veuthey, Fast analysis of doping agents by ultra performance LC, GIT Lab. J. Eur., 11, n°5-6, 14-15 (2007).
D. Guillarme, D. T.-T. Nguyen, S. Rudaz, J.-L. Veuthey, Method transfer for fast liquid chromatography in pharmaceutical analysis: Application to short columns packed with small particle. Part I: Isocratic separation, Eur. J. Pharm. Biopharm., 66, 475-482 (2007).
D. Guillarme, D. T.-T. Nguyen, S. Rudaz, J.-L. Veuthey, Recent developments in liquid chromatography - Impact on qualitative and quantitative performance, J. Chromatogr. A, 1149, 20-29 (2007).
D. T.-T. Nguyen, D. Guillarme, S. Rudaz, J.-L. Veuthey, New trend in fast liquid chromatography, Chimia, 61, 186-189 (2007).
L. Geiser, J.-L. Veuthey, Nonaqueous capillary electrophoresis in pharmaceutical analysis, Electrophor., 28, 45-57 (2007).
B. Kaufmann, S. Rudaz, S. Cherkaoui, J.-L. Veuthey, P. Christen, Influence of Plant Matrix on Microwave-assisted Extraction Process. The Case of Diosgenin Extracted from Fenugreek (Trigonella foenum-graecum L.), Phytochem. Anal., 18, 70-76 (2007).
I. Marchi, S. Rudaz, M. Selman, J.-L. Veuthey, Evaluation of the Influence of Protein Precipitation Prior to On-line SPE-LC-API/MS Procedures Using Multivariate Data Analysis, J. Chromatogr. B, 845, 244-252 (2007).
C. Stella, S. Rudaz, J.-Y. Gauvrit, P. Lantéri, A. Huteau, A. Tchapla, J.-L. Veuthey, Characterization and Comparison of the Chromatographic Performance of Different Types of Reversed-phase Stationary Phases, J. Pharm. Biomed. Anal., 43, 89-98 (2007).
M. Dreux, D. Guillarme, J-L. Veuthey, Detector being coupled with a liquid phase chromatography column and equipped with a means allowing the formation and transfer of an aerosol, Patent pending n° 0650372, 0, (2007).
E. Grata, J. Boccard, G. Glauser, P.-A. Carrupt, E. E. Farmer, J.-L. Wolfender, S. Rudaz, Development of a two step screening ESI-TOF-MS method for rapid determination of significant stress-induced metabolome modifications in plant leaf extracts: the wound response in A. thaliana as a case study, J. Sep. Sci., 30, 2268-2278 (2007).
E. Rozet, A. Ceccato, C. Hubert, E. Ziemons, R. Oprean, S. Rudaz, B. Boulanger, PH. Hubert, Analysis of recent pharmaceutical regulatory documents on analytical method validation, J. Chromatogr. A, 1158, 111-125 (2007).
P. Bonnabry, Y. Pinget, H. Ing, S. Rudaz, Evaluation et comparaison de la performance de 12 sets pour perfusion intraveineuse, Pharm. Hosp., 42, 11-17 (2007).
J. Boccard, E. Grata, A. Thiocone, J.-Y. Gauvrit, P. Lantéri, P.-A. Carrupt, J.-L. Wolfender, S. Rudaz, Multivariate data analysis of rapid LC-TOF/MS experiments from Arabidopsis thaliana stressed by wounding, Chemom. Intell. Lab. Syst., 86, 189-197 (2007).

Y. Ilias, S. Rudaz, P. Christen, J.-L. Veuthey, Headspace Solid-Phase Microextraction of Pesticide Residues in Cannabis Samples, Chimia, 60, 846-851 (2006).
P. Rubiolo, M. Matteodo, G. Riccio, M. Ballero, Ph. Christen, S. Fleury-Souverain, J.-L. Veuthey, C. Bicchi, Analytical Discrimination of Poisonous and Nonpoisonous Chemotypes of Giant Fennel (Ferula communis L.) through their Biologically Active and Volatile Fractions, J. Agri. Food Chem., 54, 7556-7563 (2006).
Y. Ilias, S. Bieri, Ph. Christen, J.-L. Veuthey, Evaluation of Solid-Phase Microextraction Desorption Parameters for Fast GC Analysis of Cocaine in Coca Leaves, J. Chromatogr. Sci., 44, 394-398 (2006).
D. T.-T. Nguyen, D. Guillarme, S. Rudaz, J.-L. Veuthey, Fast analysis in liquid chromatography using small particle size and high pressure, J. Sep. Sci., 29, 1836-1848 (2006).
D. T.-T. Nguyen, D. Guillarme, S. Rudaz, J.-L. Veuthey, Chromatographic behaviour and comparison of column packed with sub-2 Âµm stationary phases in liquid chromatography, J. Chromatogr. A, 1128, 105-113 (2006).
R. D. Marini, C. Groom, F. R. Doucet, J. Hawari, Y. Bitar, U. Holzgrabe, R. Gotti, J. Schappler, S. Rudaz, J.-L. Veuthey, R. Mol, G. W. Somsen, G. J. de Jong, P. T. T. Ha, J. Zhang, A. Van Schepdael, J. Hoogmartens, W. Brione, A. Ceccato, B. Boulanger, D. Mangelings, Y. Vander Heyden, W. Van Ael, I. Jimidar, M. Pedrini, A.-C. Servais, M. Fillet, J. Crommen, E. Rozet, Ph. Hubert, Interlaboratory study of a NACE method for the determination of R-timolol content in S-timolol maleate: Assessment of uncertainty, Electrophor., 27, 2386-2399 (2006).
S. Bieri, E. Varesio, J.-L. Veuthey, O. Muñoz, L.-H. Tseng, U. Braumann, M. Spraul, Ph. Christen, Identification of Isomeric Tropane Alkaloids from Schizanthus Grahamii by HPLC-NMR with Loop Storage and HPLC-UV-MS/SPE-NMR Using a Cryogenic Flow Probe, Phytochem. Anal., 17, 78-86 (2006).
J. Schappler, D. Guillarme, J. Prat, Veuthey, S. Rudaz, Enhanced method performances for conventional and chiral CE-ESI/MS analyses in plasma, Electrophor., 27, 1537-1546 (2006).
G. Desmet, D. Clicq, Dao T.-T. Nguyen, D. Guillarme, S. Rudaz, J.-L. Veuthey, N. Vervoort, G. Torok, D. Cabooter, P. Gzil, Practical Constraints in the Kinetic Plot Representation of Chromatographic Performance Data: Theory and Application to Experimental Data, Anal. Chem., 78, 2150-2162 (2006).
S. Bieri, Y. Ilias, C. Bicchi, J.-L. Veuthey, Ph. Christen, Focused Microwave-assisted Extraction Combined with Solid-phase Microextraction and Gas Chromatography-mass Spectrometry for the Selective Analysis of Cocaine from Coca Leaves, J. Chromatogr. A, 1112, 127-132 (2006).
S. Bieri, E. Varesio, O. Muñoz, Ph. Christen, J.-L. Veuthey, Use of Porous Graphitic Carbon Column for the Separation of Natural Isomeric Tropane Alkaloids by Capillary LC and Mass Spectrometry, J. Pharm. Biomed. Anal., 40, 545-551 (2006).
S. Bieri, A. Brachet, Ph. Christen, J.-L. Veuthey, Cocaine Distribution in Wild Erythroxylum Species, J. Ethnopharmacol., 103, 439-447 (2006).
S. Bieri, O. Muñoz, Ph. Christen, J.-L. Veuthey, Analysis of Isomeric Tropane Alkaloids from Schizanthus Grahamii by Very Fast Gas Chromatography, J. Sep. Sci., 29, 96-102 (2006).
S. Souverain, L. Geiser, S. Rudaz, J.-L. Veuthey, Strategies for rapid chiral analysis, J. Pharm. Biomed. Anal., 40, 235-241 (2006).
R. D. Marini, A.-C. Servais, E. Rozet, P. Chiap, B. Boulanger, S. Rudaz, J. Crommen, Ph. Hubert, M. Fillet, Nonaqueous capillary electrophoresis method for the enantiomeric purity determination of S-timolol using heptakis(2;3-di-O-methyl-6-O-sulfo)-beta-cyclodextrin: Validation using the accuracy profile strategy and estimation of uncertainty, J. Chromatogr. A, 1120, 102-111 (2006).
R. D. Marini, P. Chiap, B. Boulanger, S. Rudaz, E. Rozet, J. Crommen, Ph. Hubert, Comparison of three approaches for uncertainty estimation, Acta Clin. Belg., 61, 60-63 (2006).
R. D. Marini, P. Chiap, B. Boulanger, S. Rudaz, E. Rozet, J. Crommen, Ph. Hubert, Comparison of three approaches for uncertainty estimation, Acta Clin. Belg., 61, 60-63 (2006).
A. Bugey, S. Rudaz, C. Staub, A fast LC-APCI/MS method for analyzing benzodiazepines in whole blood using monolithic support, J. Chromatogr. B, 832, 249-255 (2006).
R. D. Marini, P. Chiap, B. Boulanger, S. Rudaz, E. Rozet, J. Crommen, Ph. Hubert, LC method for the determination of R-timolol in S-timolol maleate: Validation of its ability to quantify and uncertainty assessment, Talanta, 68, 1166-1175 (2006).
R. D. Marini, P. Chiap, B. Boulanger, S. Rudaz, E. Rozet, J. Crommen, PH. Hubert, LC method for the determination of R-timolol in S-timolol maleate: Validation of its ability to quantify and uncertainty assessment., Talanta, 68, 1166-1175 (2006).

N. Abla, L. Geiser, M. Mirgaldi, A. Naik, J.-L. Veuthey, R. H. Guy, Y. N. Kalia, Capillary Zone Electrophoresis for the Estimation of Transdermal Iontophoretic Mobility, J. Pharm. Sci., 94, 2667-2675 (2005).
S. Rudaz, L. Geiser, S. Souverain, J. Prat, J.-L. Veuthey, Rapid Stereoselective Separations of Amphetamine Derivatives with Highly Sulfated -cyclodextrin, Electrophor., 26, 3910-3920 (2005).
F. Schenkel, S. Rudaz, Y. Daali, M. Kondo Oestreicher, J.-L. Veuthey, P. Dayer, Development and Validation of a New Reversed-phase Ion Pairing Liquid Chromatographic Method with Fluorescence Detection for Penciclovir Analysis in Plasma and Aqueous Humor, J. Chromatogr. B, 826, 1-7 (2005).
L. Geiser, Y. Henchoz, A. Galland, P.-A. Carrupt, J.-L. Veuthey, Determination of pKa Values by Capillary Zone Electrophoresis with a Dynamic Coating Procedure, J. Sep. Sci., 28, 2374-2380 (2005).
C. Stella, A. Galland, X. Liu, B. Testa, S. Rudaz, J.-L. Veuthey, P.-A. Carrupt, Novel RPLC Stationary Phases for Lipophilicity Measurement : Solvatochromic Analysis of Retention Mechanisms for Neutral and Basic Compounds, J. Sep. Sci., 28, 2350-2362 (2005).
Y. Ilias, S. Rudaz, P. Mathieu, Ph. Christen, J.-L. Veuthey, Extraction and Analysis of Different Cannabis Samples by Headspace Solid-phase Microextraction Combined with Gas Chromatography-mass Spectrometry, J. Sep. Sci., 28, 2293-2300 (2005).
G. Kavran-Belin, S. Rudaz, J.-L. Veuthey, Enantioseparation of Baclofen with Highly Sulfated -cyclodextrin by Capillary Electrophoresis with Laser-induced Fluorescence Detection, J. Sep. Sci., 28, 2187-2192 (2005).
M. Humam, S. Bieri, L. Geiser, O. Muñoz, J.-L. Veuthey, P. Christen, Separation of Four Isomeric Tropane Alkaloids from Shizanthus Grahamii by Non-aqueous Capillary Electrophoresis, Phytochem. Anal., 16, 349-356 (2005).
C. Stella, S. Heinisch, X. Liu, P.-A. Carrupt, G. Cazorla, J.-Y. Gauvrit, P. Lantéri, K. Le Mapihan, J. Vial, S. Héron, A. Tchapla, J.-L. Rocca, J.-L. Veuthey, S. Rudaz, A study of interlaboratory influence on column evaluation, J. Pharm. Biomed. Anal., 39, 104-110 (2005).
J.-L. Veuthey, S. Rudaz, Statistical and Chemometric Tools Applied to Pharmaceutical Analysis, Chimia, 59, 326-330 (2005).
S. Rudaz, L. Geiser, D. Guillarme, J.-L. Veuthey, Development of Rapid Analytical Methods in the Laboratory of Pharmaceutical Analytical Chemistry (LCAP), Chimia, 59, 303-307 (2005).
L. Geiser, S. Rudaz, J.-L. Veuthey, Decreasing Analysis Time in Capillary Electrophoresis : Validation and Comparison of Quantitative Performances in Several Approaches, Electrophor., 26, 2293-2302 (2005).
L. Geiser, M. Mirgaldi, J.-L. Veuthey, Determination of Electroosmotic Flow in Nonaqueous Capillary Electrophoresis, J. Chromatogr. A, 1068, 75-81 (2005).
J.-L. Veuthey, Capillary Electrophoresis in Pharmaceutical and Biomedical Analysis, Anal. Bioanal. Chem., 381, 93-95 (2005).
E. Cognard, S. Rudaz, C. Staub , Analysis of cocaine and three of its metabolites in hair by gas chromatography-mass spectrometry using ion-trap detection for CI/MS/MS, J. Chromatogr. B, 826, 17-25 (2005).
L. Ayouni, G. Cazorla, D. Chaillou, B. Herbreteau, S. Rudaz, P. Lantéri, P.-A. Carrupt, Fast determination of lipophilicity in RP LC without extrapolation using aqueous eluent, Chromatographia, 62, 251-255 (2005).
F. Lallemand, O. Felt-Baeyens, S. Rudaz, A.-R. Hamel, F. Hubler, R. Wenger, M. Mutter, F. Besseghir, R. Gurny, Conversion of Cyclosporin A prodrugs in human tears vs rabbit tears, Eur. J. Pharm. Biopharm., 59, 51-56 (2005).
A. Thiocone, E. Grata, J. Boccard, P.-A. Carrupt, S. Rudaz, J.-L. Wolfender, Synergy at the "Ecole de Pharmacie Genève-Lausanne": methodology developments for the treatment of complex metabolomic datasets with data mining, Chimia, 26, 362-365 (2005).
J.-L. Veuthey, L'électrophorèse et l'électrochromatographie, Spectra Anal., 243, 3 (2005).

S. Souverain, S. Rudaz, J.-L. Veuthey, Matrix Effect in LC-ESI-MS and LC-APCI-LC-MS with off-line and on-line extraction procedures, J. Chromatogr. A, 1058, 61-66 (2004).
S. Rudaz, T. Le Saux, J. Prat, P. Gareil, J.-L. Veuthey, Ultrashort partial-filling technique in capillary electrophoresis for infinite resolution of tramadol enantiomers and its metabolites with highly sulfated cyclodextrins, Electrophor., 25, 2761-2771 (2004).
E. Calleri, C. Temporini, E. Perani, C. Stella, S. Rudaz, D. Lubda, G. Mellerio, J.-L. Veuthey, G. Caccialanza, G. Massolini, Development of a Bioreactor Based on Trypsin Immobilized on Monolithic Support for the On-line Digestion and Identification of Proteins, J. Chromatogr. A, 1045, 99-109 (2004).
Y. Ilias, S. Rudaz, P. Mathieu, J.-L. Veuthey, Ph. Christen, Analysis of Cannabis Material by Headspace Solid-Phase Microextraction Combined with Gas Chromatrography-Mass Spectrometry, Chimia, 58, 219-221 (2004).
S. Souverain, S. Rudaz, J.-L. Veuthey, Protein Precipitation for the Analysis of a Drug Cocktail in Plasma by LC-ESI-MS, J. Pharm. Biomed. Anal., 35, 913-920 (2004).
J.-L. Veuthey, S. Souverain, S. Rudaz, Column-Switching Procedures for the Fast Analysis of Drugs in Biologic Samples, Ther. Drug Monit., 26, 161-166 (2004).
M. Gex-Fabry, A. E. Balant-Gorgia, L. P. Balant, S. Rudaz, J.-L. Veuthey, G. Bertschy, Time Course of Clinical Response to Venlafaxine: Relevance of Plasma Level and Chirality, Eur. J. Clin. Pharmacol., 59, 883-891 (2004).
C. Stella, S. Rudaz, M. Mottaz, P.-A. Carrupt, J.-L. Veuthey, Analysis of Basic Compounds at High pH Values by Reversed-phase Liquid Chromatography, J. Sep. Sci., 27, 284-292 (2004).
S. Souverain, S. Rudaz, J.-L. Veuthey, Restricted Access Material and Large Particle Supports for on-line Sample Preparation: an Attractive Approach for Biological Fluid Analysis, J. Chromatogr. B, 801, 141 (2004).

S. Souverain, C. Eap, J.-L. Veuthey, S. Rudaz, Automated LC-MS Method for the Fast Stereoselective Determination of Methadone in Plasma, Clin. Chem. Lab. Med., 41, 1615-1621 (2003).
S. Souverain, M. Mottaz, S. Cherkaoui, J.-L. Veuthey, Rapid Analysis of Fluoxetine and its Metabolite in Plasma by LC-MS with Column-switching Approach, Anal. Bioanal. Chem., 377, 880-885 (2003).
L. Geiser, S. Rudaz, J.-L. Veuthey, Validation of Capillary Electrophoresis-mass Spectrometry Methods for the Analysis of a Pharmaceutical Formulation, Electrophor., 24, 3049-3056 (2003).
S. Rudaz, S. Souverain, C. Schelling, M. Deleers, A. Klomp, A. Norris, T.L. Vu, B. Ariano, J.-L. Veuthey, Development and Validation of a Heart-cutting Liquid Chromatography-mass Spectrometry Method for the Determination of Process-related Substances in Cetirizine Tablets, Anal. Chim. Acta., 492, 271-282 (2003).
S. Rudaz, E. Calleri, L. Geiser, S. Cherkaoui, J. Prat, J.-L. Veuthey, Infinite Enantiomeric Resolution of Basic Compounds Using Highly Sulfated Cyclodextrin as Chiral Selector in Capillary Electrophoresis, Electrophor., 24, 2633-2641 (2003).
S. Descroix, A. Varenne, L. Geiser, S. Cherkaoui, J.-L. Veuthey, P. Gareil, Influence of Electrolyte Nature on the Separation Selectivity of Amphetamines in Nonaqueous Capillary Eectrophoresis: Protonation Degree versus Ion Pairing Effects, Electrophor., 24, 1577-1586 (2003).
C. Stella, P. Seuret, S. Rudaz, P.-A. Carrupt, J.-Y. Gauvrit, P. Lanteri, J.-L. Veuthey, An Effective Tool for Column Evaluation in the Analysis of Basic Compounds, Chimia, 57, 210-213 (2003).
S. Souverain, S. Rudaz, J.-L. Veuthey, Use of Monolithic Supports for Fast Analysis of Drugs and Metabolites in Plasma by Direct Injection, Chromatographia, 57, 569-575 (2003).
S. Souverain, S. Rudaz, J.-L. Veuthey, New Extraction Support for the Fast Analysis of Pharmaceutical Compounds in Biological Samples by Direct Injection., GIT Lab. J., 2, 80-82 (2003).
L. Geiser, E. Varesio, J.-L. Veuthey, Simultaneous Analysis of Metabisulfite and Sulfate by CE with Indirect UV Detection. Application to and Validation for a Pharmaceutical Fomulation, J. Pharm. Biomed. Anal., 31, 1059-1064 (2003).
P. Dehouck, Y. Vander Heyden, J. Smeyers-Verbeke, D. L. Massart, J. Crommen, Ph. Hubert, R. D. Marini, O.S.N.M. Smeets, G. Decristoforo, W. Van de Wauw, J. De Beer, M. G. Quaglia, C. Stella, J.-L. Veuthey, O. Estevenon, A. Van Schepdael, E. Roets, J. Hoogmartens, Determination of Uncertainty in Analytical Measurements from Collaborative Study Results on the Analysis of a Phenoxymethylpenicillin Sample, Anal. Chim. Acta., 481, 261-272 (2003).
S. Souverain, S. Rudaz, D. Ortelli, E. Varesio, J.-L. Veuthey, Use of Large Particles Support for Fast Analysis of Methadone and its Primary Metabolite in Human Plasma by Liquid Chromatography-mass Spectrometry, J. Chromatogr. B, 784, 117-123 (2003).
S. Cherkaoui, X. Cahours, J.-L. Veuthey, Analysis of Selected Withanolides in Plant Extract by Capillary Electrochromatography and Microemulsion Electrokinetic Chromatography. Attention : erreur d'édition : cet article est paru dans le volume 24 (2003) mais l'article est daté et numéroté 23 (2002) / 23, 336-342 (2002), Electrophor., 24, 336-342 (2003).
L. Geiser, S. Cherkaoui, J.-L. Veuthey, Potential of Formamide and N-Methylformamide in Nonaqueous Capillary Electrophoresis Coupled to Electrospray Ionization Mass Spectrometry: Application to the Analysis of Beta-Blockers, J. Chromatogr. A, 979, 389-398 (2002).
C. Stella, P. Seuret, S. Rudaz, P.-A. Carrupt, J.-Y Gauvrit, P. Lanteri, J,-L. Veuthey, Characterization of Chromatographic Supports for the Analysis of Basic Compounds, J. Sep. Sci., 25, 1351-1363 (2002).
C. Stella, P. Seuret, S. Rudaz, A. Tchapla, J.-Y. Gauvrit, P. Lanteri, J.-L. Veuthey, Simplification of a Chromatographic Test Methodology for the Evaluation of Base Deactivated Supports, Chromatographia, 56, 665-671 (2002).
C. Desiderio, S. Rudaz, J.-L. Veuthey, M.-A. Raggi, S. Fanali, Use of Vancomycin Silica Stationary Phase in Packed Capillary Electrochromatography. Part IV: Enantiomer Separation of Fluoxetine and Norfluoxetine Employing UV High Sensitivity Detection Cell, J. Sep. Sci., 25, 1291-1296 (2002).
S. Souverain, S. Rudaz, J.-L. Veuthey, Nouveaux supports d'extraction en phase solide pour l'analyse rapide de substances pharmaceutiques, BIOforum International, 2, 34-36 (2002).
B. Kaufmann, S. Souverain, S. Cherkaoui, P. Christen, J.-L. Veuthey, Rapid Liquid Chromatographic-Mass Spectrometric Analysis of Withanolides in Crude Plant Extracts by use of a Monolithic Column, Chromatographia, 56, 137-141 (2002).
S. Cherkaoui, J.-L. Veuthey, Micellar and Microemulsion Electrokinetic Chromatography of Selected Anesthetic Drugs, J. Sep. Sci., 25, 1073-1078 (2002).
E. Varesio, S. Rudaz, K. H. Krause, J.-L. Veuthey, Nanoscale Liquid Chromatography and Capillary Electrophoresis Coupled to Electrospray Mass Spectrometry for the Detection of Amyloid-β Peptide related to Alzheimer's Disease, J. Chromatogr. A, 974, 135-142 (2002).
M. Gex-Fabry, S. Rudaz, A. E. Balant-Gorgia, A. Brachet, J.-L. Veuthey, L.P Balant, G. Bertschy, Steady-State Concentration of Venlafaxine Enantiomers: Model-Based Analysis of Between Patient Variability, Eur. J. Clin. Pharmacol., 58, 323-331 (2002).
X. Cahours, S. Cherkaoui, G. Rozing, J.-L. Veuthey, MEEKC-UV Versus CEC-UV-MS for the Analysis of Flunitrazepam and its Major Metabolites, Electrophor., 23, 2320-2326 (2002).
A. Brachet, P. Christen, J.-L. Veuthey, Focused Microwave-assisted Extraction of Cocaine and Benzoylecgonine from Coca Leaves, Phytochem. Anal., 13, 162-169 (2002).
Y. Daali, S. Cherkaoui, X. Cahours, E. Varesio, J.-L. Veuthey, High Performance Liquid Chromatography of Acarbose and its Metabolite on Porous Graphitic Carbon Column, J. Sep. Sci., 25, 280-284 (2002).
S. Cherkaoui, J.-L. Veuthey, Nonaqueous Capillary Electrophoresis- Electrospray-Mass Spectrometry for the Analysis of Fluoxetine and its Related Compounds, Electrophor., 23, 442-448 (2002).
D. Ortelli, S. Rudaz, S. Souverain, J.-L. Veuthey, Restricted Access Materials for Fast Analysis of Methadone in Serum with Liquid Chromatography-Mass Spectrometry, J. Sep. Sci., 25, 222-228 (2002).
X. Cahours, Y. Daali, S. Cherkaoui, J.-L. Veuthey, Simultaneous Analysis of Polyhydroxylated Alkaloids by Capillary Electrophoresis Using Borate Complexation and Evaluation of Sweeping Technique for Sensitivity Improvement, Chromatographia, 55, 211-216 (2002).
S. Cherkaoui, J.-L. Veuthey, Use of Negatively Charged Cyclodextrins for the Simultaneous Enantioseparation of Selected Anesthetic Drugs by Capillary Electrophoresis Mass Spectrometry, J. Pharm. Biomed. Anal., 27, 615-626 (2002).
A. Brachet, S. Rudaz, L. Mateus, P. Christen, J.-L. Veuthey, Optimisation of Accelerated Solvent Extraction of Cocaine and Benzoylecgonine from Coca Leaves, J. Sep. Sci., 24, 865-873 (2001).
P. Christen, J.-L. Veuthey, New Trends in Extraction, Identification and Quantification of Artemisinin and its Derivatives, Curr. Med. Chem., 8, 1827-1839 (2001).
N.T. Tran, Y. Daali, S. Cherkaoui, M. Taverna, J.R. Neeser, J.-L. Veuthey, Routine O-glycan Characterization in Nutritional Supplements - A Comparison of Analytical Methods for the Monitoring of the Bovine Kappa-casein Macropeptide Glycosylation, J. Chromatogr. A, 929, 151-163 (2001).
S. Rudaz, S. Cherkaoui, J.Y. Gauvrit, P. Lantéri, J.-L. Veuthey, Experimental Designs to Investigate CE-ESI-MS Enantioseparation With the Partial-Filling Technique, Electrophor., 22, 3316-3326 (2001).
K. Bekkouche, Y. Daali, S. Cherkaoui, J.-L. Veuthey, P. Christen, Calystegine Distribution in some Solanaceous Species, Phytochemistry, 58, 455-462 (2001).
B. Kaufmann, P. Christen, J.-L. Veuthey, Study Factors Influencing Pressurised Solvent Extraction of Polar Steroids from Plant Material. Application to the Recovery of Withanolides, Chromatographia, 54, 394-398 (2001).
B. Kaufmann, P. Christen, J.-L. Veuthey, Parameters Affecting Microwave-assisted Extraction of Withanolides, Phytochem. Anal., 12, 327-331 (2001).
S. Cherkaoui, S. Rudaz, E. Varesio, J.-L. Veuthey, On-line Capillary Electrophoresis-Electrospray Mass Spectrometry for the Stereoselective Analysis of Drugs and Metabolites, Electrophor., 22, 3308-3315 (2001).
S. Cherkaoui, K. Bekkouche, P. Christen, J.-L. Veuthey, Non-Aqueous Capillary Electrophoresis with Diode Array and Electrospray Mass Spectrometric Detection for the Analysis of Selected Steroidal Alkaloids in Plant Extracts, J. Chromatogr. A, 922, 321-328 (2001).
S. Fanali, S. Rudaz, J.-L. Veuthey, C. Desiderio, Use of Vancomycin Silica Stationary Phase in Packed Capillary Electrochromatography. II. Enantiomer Separation of Venlafaxine and O-desmethylvenlafaxine in Human Plasma, J. Chromatogr. A, 919, 195-203 (2001).
C. Stella, S. Rudaz, J.-L. Veuthey, A. Tchapla, Silica and Other Materials as Supports in Liquid Chromatography. Chromatographic Tests and their Importance for Evaluating these Supports. Part II, Chromatographia, 53, S-132-S-140 (2001).
C. Stella, S. Rudaz, J.-L. Veuthey, A. Tchapla, Silica and Other Materials as Supports in Liquid Chromatography. Chromatographic Tests and their Importance for Evaluating these Supports. Part I, Chromatographia, 53, S-113-S-131 (2001).
C. Bicchi, G. Appendino, C. Cordero, P. Rubiolo, D. Ortelli, J.-L. Veuthey, HPLC-UV and HPLC-Positive-ESI-MS Analysis of the Diterpenoid Fraction from Caper Spurge (Euphorbia Lathyris) Seed Oil, Phytochem. Anal., 12, 255-262 (2001).
Y. Daali, S. Cherkaoui, J.-L. Veuthey, Capillary Electrophoresis and High-Performance Anion Exchange Chromatography for Monitoring Caseinoglycomacropeptide Sialylation, J. Pharm. Biomed. Anal., 24, 849-856 (2001).
S. Cherkaoui, S. Rudaz, J.-L. Veuthey, Nonaqueous Capillary Electrophoresis-Mass Spectrometry for Separation of Venlafaxine and its Phase I Metabolites, Electrophor., 22, 491-496 (2001).
S. Einmahl, F. Behar-Cohen, F. D'Hermies, S. Rudaz, C. Tabatabay, G. Renard, R. Gurny, A new poly(ortho ester)-based drug delivery system for the adjunct treatment of filtering surgery, Invest. Ophtalmol. Visual Sci., 42, 695-700 (2001).
Y. Daali, K. Bekkouche, S. Cherkaoui, P. Christen, J.-L. Veuthey, Use of Borate Complexation for the Separation of Non-UV-Absorbing Calystegines by Capillary Electrophoresis, J. Chromatogr. A, 903, 237-244 (2000).
M. Zignani, S. Einmahl, V. Baeyens, E. Varesio, J.-L. Veuthey, J. Anderson, J. Heller, C. Tabatabay, R. Gurny, A Poly(ortho ester) Designed for Combined Ocular Delivery of Dexamethasone Sodium Phosphate and 5-Fluorouracil: Subconjunctival Tolerance and In Vitro Release, Eur. J. Pharm. Biopharm., 50, 251-255 (2000).
D. Ortelli, S. Rudaz, E. Cognard, J.-L. Veuthey, Analysis of Dihydroartemisinin in Plasma by Liquid Chromatography-Mass Spectrometry, Chromatographia, 52, 445-450 (2000).
S. Cherkaoui, L. Geiser, J-L Veuthey, Rapid Separation of Basic Drugs by Nonaqueous Capillary Electrophoresis, Chromatographia, 52, 403-407 (2000).
L. Geiser, S. Cherkaoui, J.-L. Veuthey, Simultaneous Analysis of Some Amphetamine Derivatives in Urine by Nonaqueous Capillary Electrophoresis Coupled to Electrospray Ionization Mass Spectrometry, J. Chromatogr. A, 895, 111-121 (2000).
S. Rudaz, C. Stella, A.E. Balant-Gorgia, S. Fanali, J.-L. Veuthey, Simultaneous Stereoselective Analysis of Venlafaxine and O-Desmethylvenlafaxine Enantiomers in Clinical Samples by Capillary Electrophoresis Using Charged Cyclodextrins, J. Pharm. Biomed. Anal., 23, 107-115 (2000).
A. Brachet, P. Christen, J.Y. Gauvrit, R. Longeray, P. Lantéri, J.-L. Veuthey, Experimental Design in Supercritical Fluid Extraction of Cocaine from Coca Leaves, J. Biochem. Biophys. Methods, 43, 353-366 (2000).
S. Cherkaoui, J.-L. Veuthey, Development and Robustness Testing of a Nonaqueous Capillary Electrophoresis Method for the Analysis of Non Steroidal Anti-inflammatory Drugs, J. Chromatogr. A, 874, 121-129 (2000).
L. Mateus, S. Cherkaoui, P. Christen, J.-L. Veuthey, Enantioseparation of Atropine by Capillary Electrophoresis Using Sulfated-β-Cyclodextrin : Application to a Plant extract, J. Chromatogr. A, 868, 285-294 (2000).
S. Rudaz, S. Cherkaoui, P. Dayer, S. Fanali, J.-L. Veuthey, Simultaneous Stereoselective Analysis of Tramadol and its Main Phase I Metabolites by On-line Capillary Zone Electrophoresis-Electrospray Ionization Mass Spectrometry, J. Chromatogr. A, 868, 295-303 (2000).
D. Ortelli, S.Rudaz, A.F. Chevalley, A. Mino, J.J. Deglon, L. Balant, J.-L. Veuthey, Enantioselective Analysis of Methadone in Saliva by Liquid Chromatography-Mass Spectrometry, J. Chromatogr. A, 871, 163-172 (2000).
L. Mateus, S. Cherkaoui, P. Christen, J.-L. Veuthey, Application of Micellar Electrokinetic Chromatography to the Determination of Some Tropane Alkaloids in Various Plant extracts, Current Topics in Phytochemistry, 2, 175-182 (1999).
S. Cherkaoui, J.-L. Veuthey, Separation of Selected Anesthetic Drugs by Nonaqueous Capillary Electrophoresis, Analusis, 27, 765-771 (1999).
A. Brachet, L. Mateus, S. Cherkaoui, P. Christen, J.-Y. Gauvrit, P. Lantéri, J.-L. Veuthey, Application of Central Composite Designs in the Supercritical Fluid Extraction of Tropane Alkaloids in Plant Extracts, Analusis, 27, 772-778 (1999).
L. Mateus, S. Cherkaoui, P. Christen, J.-L. Veuthey, Capillary Electrophoresis-Diode Array Detection-Electrospray Mass Spectrometry for the Analysis of Selected Tropane Alkaloids in Plant Extracts, Electrophor., 20, 3402-3409 (1999).
S. Cherkaoui, S. Rudaz, E. Varesio, J.-L. Veuthey, On-line Capillary Electrophoresis-Electrospray Mass Spectrometry for the Analysis of Pharmaceuticals, Chimia, 53, 501-505 (1999).
Y. Daali, S. Cherkaoui, P. Christen, J.-L. Veuthey, Experimental Design for Enantioselective Separation of Celiprolol by Capillary Electrophoresis using Sulfated β-Cyclodextrin, Electrophor., 20, 3424-3431 (1999).
S. Einmahl, M. Zignani, E. Varesio, J. Heller, J.-L. Veuthey, C. Tabatabay, R. Gurny, Concomitant and Controlled Release of Dexamethasone and 5-Fluorouracil from Poly(ortho ester), Int. J. Pharm., 185, 189-198 (1999).
S. Rudaz, J.-L. Veuthey, C. Desiderio, S. Fanali, Enantioseparation of Venlafaxine and O-Desmethylvenlafaxine by Capillary Electrophoresis with Mixed Cyclodextrins, Chromatographia, 50, 369-372 (1999).
S. Cherkaoui, F. Pitré, J.R. Neeser, J.-L. Veuthey, Determination of the Stability of Caseinoglycomacropeptide in a Cosmetic Lotion by Use of Capillary Zone Electrophoresis with a Coated Capillary, Chromatographia, 50, 311-316 (1999).
S. Cherkaoui, L Mateus, P. Christen, J.-L. Veuthey, Nonaqueous Versus Aqueous Capillary Electrophoresis for the Dosage of N-butylscopolamine in Various Pharmaceutical Formulations, J. Pharm. Biomed. Anal., 21, 165-174 (1999).
A. Salvador, E. Varesio, M. Dreux, J.-L. Veuthey, Binding Constants Dependency of Amphetamines with Various Commercial Methylated β-Cyclodextrins, Electrophor., 20, 2670-2679 (1999).
E. Varesio, J.Y. Gauvrit, R. Longeray, P. Lantéri, J.-L. Veuthey, Optimization of Fast CE Analyses of Ecstasy Derivatives by Use of Experimental Designs, Chromatographia, 50, 195-201 (1999).
S. Rudaz, J.-L. Veuthey, C. Desiderio, S. Fanali, Simultaneous Stereoselective Analysis by Capillary Electrophoresis of Tramadol Enantiomers and their Main Phase I Metabolites in Urine, J. Chromatogr. A, 846, 227-237 (1999).
S. Rudaz, D. Ortelli, M. Gex-Fabry, J.-J. Déglon, L. Balant, J.-L. Veuthey, Development of Validated Stereoselective Methods for Methadone Determination in Clinical Samples, Chirality, 11, 487-494 (1999).
S. Rudaz, J.-L. Veuthey, Chiral Stationary Phases in HPLC for the Stereoselective Determination of Methadone, Chirality, 11, 319-325 (1999).
S. Cherkaoui, L. Mateus, P. Christen, J.-L. Veuthey, Nonaqueous Capillary Electrophoresis for the Analysis of Selected Tropane Alkaloids in a Plant Extract, Chromatographia, 49, 54-60 (1999).
C. Desiderio, S. Rudaz, M.-A. Raggi, S. Fanali, Enantiomeric separation of fluoxetine and norfluoxetine in plasma and serum samples with high detection sensitivity capillary electrophoresis, Electrophor., 20, 3432-3438 (1999).
S. Rudaz, J.-L. Veuthey, C. Desiderio, S. Fanali, Use of Cyclodextrins in Capillary Electrophoresis. Resolution of Tramadol Enantiomers, Electrophor., 19, 2883-2889 (1998).
S. Cherkaoui, E. Varesio, P. Christen, J.-L. Veuthey, Selectivity Manipulation using Nonaqueous Capillary Electrophoresis. Application to Tropane Alkaloids and Amphetamine Derivatives, Electrophor., 19, 2900-2906 (1998).
L. Mateus, S. Cherkaoui, P. Christen, J.-L. Veuthey, Use of a Doehlert Design in Optimizing the Analysis of Selected Tropane Alkaloids by Micellar Electrokinetic Capillary Chromatography, J. Chromatogr. A, 829, 317-325 (1998).
E. Varesio, S. Cherkaoui, J.-L. Veuthey, Optimization of CE-ESI-MS Parameters for the Analysis of Ecstasy and Derivatives in Urine, J. High Resolut. Chromatogr., 21, 653-657 (1998).
S. Cherkaoui, Y. Daali, P. Christen, J.-L. Veuthey, Development and Validation of Liquid Chromatography and Capillary Electrophoresis Methods for Acarbose Determination in Pharmaceutical Tablets, J. Pharm. Biomed. Anal., 18, 729-735 (1998).
L. Mateus, S. Cherkaoui, P. Christen, J.-L. Veuthey, Capillary Electrophoresis for the Analysis of Tropane Alkaloids. Pharmaceutical and Phytochemical Applications, J. Pharm. Biomed. Anal., 18, 815-825 (1998).
S. Cherkaoui, L. Mateus, P. Christen, J.-L. Veuthey, Validated Capillary Electrophoresis Method for the Determination of Atropine and Scopolamine Derivatives in Pharmaceutical Formulations, J. Pharm. Biomed. Anal., 17, 1167-1176 (1998).
C. Giroud, M. Augsburger, L. Rivier, P. Mangin, F. Sadeghipour, E. Varesio, J.-L. Veuthey, P. Kamalaprija, 2-CB : A new Psychoactive Phenylethylamine Recently Discovered in "Ecstasy" Tablets Sold on the Swiss Black Market, J. Anal. Toxicol., 22, 345-354 (1998).
F. Sadeghipour, J.-L. Veuthey, Automated On-line Dialysis and Liquid Chromatography of Methylenedioxylated Amphetamines in Plasma and Serum Samples, J. Pharm. Biomed. Anal., 17, 801-810 (1998).
V. Bayens, V. Kaltsatos, B. Boisramé, E. Varesio, J.-L. Veuthey, M. Fathi, L.P. Balant, M. Gex-Fabry, R. Gurny, Optimized Release of Dexamethasone and Gentamicin from a Soluble Ocular Insert for the Treatment of External Ophthalmic Infections, J. Controlled Release, 52, 215-220 (1998).
F. Sadeghipour, J.-L. Veuthey, Enantiomeric Separation of Four Methylenedioxylated Amphetamines on β-Cyclodextrin Chiral Stationary Phases, Chromatographia, 47, 285-290 (1998).
A. Brachet, O. Muñoz, M. Gupta, J.-L. Veuthey, P. Christen, Alkaloids of Erythroxylum Lucidum Steam-Bark, Phytochemistry, 46, 1439-1442 (1997).
S. Cherkaoui, N. Doumenc, P. Tachon, J.R. Neeser, J.-L. Veuthey, Development of a Capillary Zone Electrophoresis Method for Caseinoglycomacropeptide Determination, J. Chromatogr. A, 790, 195-205 (1997).
F. Sadeghipour, J.-L. Veuthey, Sensitive and Selective Determination of Methylenedioxylated Amphetamines by HPLC with Fluorimetric Detection, J. Chromatogr. A, 787, 137-143 (1997).
M. Kohler, W. Haerdi, P. Christen, J.-L. Veuthey, Extraction of Artemisinin and Artemisinic Acid from Artemisia annua L. using Supercritical Carbon Dioxide, J. Chromatogr. A, 785, 353-360 (1997).
S. Cherkaoui, L. Mateus, P. Christen, J.-L. Veuthey, Micellar Electrokinetic Capillary Chromatography for Selected Tropane Alkaloid Analysis in Plant Extract, Chromatographia, 46, 351-357 (1997).
M. Kohler, W. Haerdi, P. Christen, J.-L. Veuthey, The Evaporative Light Scattering Detector : some Applications in Pharmaceutical Analysis, Trends Anal. Chem., 16, 475-484 (1997).
M. Kohler, W. Haerdi, P. Christen, J.-L. Veuthey, Supercritical Fluid Extraction and Chromatography of Artemisinin and Artemisinic Acid. An Improved Method for the Analysis of Artemisia Annua Samples, Phytochem. Anal., 8, 223-227 (1997).
S. Cherkaoui, L. Mateus, P. Christen, J.-L. Veuthey, Development and Validation of a Capillary Zone Electrophoresis Method for the Determination of Atropine, Homatropine and Scopolamine in Ophtalmic Solutions, J. Chromatogr. B, 696, 283-290 (1997).
E. Varesio, J.Y. Gauvrit, R. Longeray, P. Lantéri, J.-L. Veuthey, Central Composite Design in the Chiral Analysis of Amphetamines by Capillary Electrophoresis, Electrophor., 18, 931-937 (1997).
C. Giroud, M. Augsburger, F. Sadeghipour, E. Varesio, J.-L. Veuthey, L. Rivier, P. Mangin, Ecstasy et "Raves"en Suisse Romande, Toxicorama, IX, 113-122 (1997).
V. Bayens, E. Varesio, J.-L. Veuthey, R. Gurny, Determination of Dexamethasone in Tears by Capillary Electrophoresis, J. Chromatogr. B, 692, 222-226 (1997).
F. Sadeghipour, E. Varesio, C. Giroud, L. Rivier, J.-L. Veuthey, Analysis of Amphetamines by Capillary Electrophoresis and Liquid Chromatography- Application to Drug Seizures and Cross-validation, Forensic Sci. Intern., 86, 1-13 (1997).
S. Rudaz, W. Haerdi, J.-L. Veuthey, Evaluation of Solid Phase Extraction Procedures of I125-Methadone in serum on Discs and Cartridges, Chromatographia, 44, 283-288 (1997).
F. Sadeghipour, C. Giroud, L. Rivier, J.-L. Veuthey, Rapid Determination of Amphetamines by HPLC with UV Detection, J. Chromatogr. A, 761, 71-78 (1997).
C. Giroud, M. Augsburger, F. Sadeghipour, E. Varesio, J.-L. Veuthey, L. Rivier, Ecstasy - la Situation en Suisse Romande: Composition des Saisies, Analyse des Echantillons Biologiques et Brève Revue de son Action Pharmacologique et de sa Toxicité., Praxis, 86, 510-523 (1997).
M. Kohler, W. Haerdi, P. Christen, J.-L. Veuthey, Determination of Artemisinin and Artemisinic Acid by Capillary and Packed Supercritical Fluid Chromatography, J. High Resolut. Chromatogr., 20, 62-66 (1997).
M. Saugy, C. Cardis, C. Schweizer, J.-L. Veuthey, L. Rivier, Detection of Human Growth Hormone Doping in Urine: Out of Competition Tests Are Necessary, J. Chromatogr. B, 687, 201-211 (1996).
S. Rudaz, J.-L. Veuthey, Stereoselective Determination of Methadone in Serum by HPLC following Solid-Phase Extraction on Disk, J. Pharm. Biomed. Anal., 14, 1271-1279 (1996).
F. Brun, J.-L. Veuthey, Validation of HPLC Methods on two Silica Base-Deactivated Reversed Phases for the Analysis of Basic Drugs, J. Pharm. Biomed. Anal., 14, 1251-1259 (1996).
P. Bonnabry, J. Desmeules, S. Rudaz, T. Leemann, J.-L. Veuthey, P. Dayer, Stereoselective Interaction between Piroxicam and Acenocoumarol, Br. J. Clin. Pharmacol, 41, 525-530 (1996).
E. Varesio, J.-L. Veuthey, Chiral Separation of Amphetamines by High-Performance Capillary Electrophoresis, J. Chromatogr. A, 717, 219-228 (1995).
J.-L.Veuthey, P. Edder, C. Staub, Depistage des Toxicomanies au moyen de l'Extraction en Phase Supercritique couplée à la CPG-SM: Applications à l'Urine et aux Cheveux, Analusis, 23, 258-265 (1995).
P. Castioni, P. Christen, J.-L. Veuthey, L'extraction en Phase Supercritique des Substances d'Origine Végétale, Analusis, 23, 95-106 (1995).
P. Edder, C. Staub, J.-L. Veuthey, I. Pierroz, W. Haerdi, Subcritical Fluid Extraction of Opiates in Hair of Drug Addicts, J. Chromatogr. Biomed. Appl., 658, 75-86 (1994).
P. Edder, J.-L. Veuthey, M. Kohler, C. Staub, W. Haerdi, Sub-Critical Fluid Extraction of Morphinic Alkaloids in Urine and Other Liquid Matrices After Adsorption on Solid Supports, Chromatographia, 38, 35-42 (1994).
A. Coquet, W. Haerdi, R. Degli Agosti, J.-L. Veuthey, Determination of Sugars by Liquid Catalytic Derivatization and Fluorescence Detection, Chromatographia, 38, 12-16 (1994).
A. Coquet, J.-L. Veuthey, W. Haerdi, Comparison of Post-Column Fluorescence Derivatization and Evaporative Light-Scattering Detection to Analyse Saccharides Selectively by LC, Chromatographia, 34, 651-654 (1992).
P. Edder, W. Haerdi, J.-L. Veuthey, C. Staub, Capillary Supercritical Chromatography and Quantitative Supercritical Fluid Extraction of Basic Drugs of Abuse, Chimia, 46, 141-148 (1992).
A. Coquet, J.-L. Veuthey, W. Haerdi, R. Degli Agosti, Applications of a Post-Column Fluorigenic Reaction in Liquid Chromatography for the Determination of Glucose and Fructose in Biological Matrices, Anal. Chim. Acta., 252, 173-179 (1991).
A. Coquet, J.-L. Veuthey, W. Haerdi, Selective Post-column Fluorogenic Reaction with Benzamidine for Trace Level Detection of Reducing Saccharides in Liquid Chromatography, J. Chromatogr., 553, 255-263 (1991).
A. Coquet, A.A. Descombes, J.-L. Veuthey, W. Haerdi. Frez, Comparison between Phenylboronic acid and Iron-Loaded Silicas to Selectively Preconcentrate Catecholamines On-line Coupled with HPLC, Z. Anal. Chem., 339, 475-479 (1991).
A.A. Descombes, J.-L. Veuthey, W. Haerdi. Frez, Optimization of Derivatization Parameters with 9-Fluorenylmethyl Chloroformate for Amphetamines and Catecholamines Separation by Supercritical Fluid Chromatography, Z. Anal. Chem., 339, 480-484 (1991).
G. Maeder, M. Pelletier, J.-L. Veuthey, W. Haerdi, Determination Spectrophotométrique de l'Ethanol dans le Sang par FIA avec Réacteur Enzymatique Couplé à un Dialyseur, Trav. Chim. Aliment. Hyg., 81, 209-218 (1990).
M.A. Bagnoud, W. Haerdi, J.-L. Veuthey, Outer-Sphere Ligand Exchange Chromatography with a Copper-Loaded Macrocyclic-Bonded Silica Column, Chromatographia, 29, 495-499 (1990).
G. Hopfgartner, J.-L.Veuthey, F.O. Gülaçar, A. Buchs, Extraction of Biomarkers from Sediments with Supercritical Carbon Dioxide: a Comparative Study with the Solvent Extraction and the Thermodesorption Method, Org. Geochem., 15, 397-402 (1990).
J.-L. Veuthey, W. Haerdi, Separation of Amphetamines by Supercritical Fluid Chromatography, J. Chromatogr., 515, 385-390 (1990).
G. Maeder, J.-L. Veuthey, M. Pelletier, W. Haerdi, A Novel Spectrophotometric Determination of Ethanol in Blood Using a Flow-Injection System with an Immobilized Enzyme (Alcohol Dehydrogenase) Reactor Coupled to on-line Dialyser, Anal. Chim. Acta., 231, 115-119 (1990).
J.-L. Janicot, M. Caude, R. Rosset, J.-L. Veuthey, Extraction of Major Alkaloids from Poppy Straw with Subcritical Mixtures of Carbon Dioxide and Polar Modifiers, J. Chromatogr., 505, 247-256 (1990).
J.-L. Veuthey, J.-L. Janicot, M. Caude, R. Rosset, Comparative Supercritical Chromatographic Properties of CO2 and SF6-NH3 Mixtures with Packed Columns, J. Chromatogr., 499, 637-643 (1990).
J.-L. Veuthey, M. Caude, R. Rosset, Couplage de l'Extraction et de la Chromatographie en Phase Supercritique avec des Chromatographies, Analusis, 18, 103-111 (1990).
J.-L. Veuthey, W. Haerdi, Copper (II) - Dialkyldithiocarbamate Silica Pre-column for the Enrichment of complexing Analytes in Natural Media, On-line Coupled with HPLC, Anal. Chim. Acta., 225, 303-311 (1989).
J.-L. Veuthey, M.A. Bagnoud, A. Descombes, W. Haerdi, Extraction Liquide-Solide Sélective au Moyen de Silices Métalliques, Trav. Chim. Aliment. Hyg., 80, 223-230 (1989).
J.-L. Veuthey, M. Caude, R. Rosset, Separation of some Amino Acids by SFC after a Pre-derivatization Step with Classical Reagents, Chromatographia, 27, 105-108 (1989).
J.-L. Veuthey, M. Caude, R. Rosset, La chromatographie en Phase Supercritique Micellaire Inverse est-elle possible ?, Analusis, 16, 466-468 (1988).
J.-L. Veuthey, J.P. Senn, W. Haerdi, Low-cost Rapid Separation and Determination of Ionic Species by Single-Column Ion Chromatography, J. Chromatogr., 445, 183-188 (1988).
J.-L. Veuthey, M.A. Bagnoud, W. Haerdi, Enrichment of a Copper-loaded-Silica Surface of Amino Acids and On-line Coupling with Ion Pairing Chromatography, J. Chromatogr., 393, 51-56 (1987).
M.A. Bagnoud, J.-L. Veuthey, W. Haerdi, Etude des Interactions Silice Métallique-soluté. Possibilités d'Applications en Préconcentration et en Chromatographie d'Echange de Ligands, Chimia, 40, 432-434 (1986).
J.-L. Veuthey, M.A. Bagnoud, W. Haerdi, Rétention d'Acides Aminés sur Silice chargée en Cuivre, Chimia, 40, 353-356 (1986).
J.-L. Veuthey, M.A. Bagnoud, W. Haerdi, Enrichment of Amino and Carboxylic Acids using Copper-loaded Silica Pre-columns Coupled One-line with HPLC, Int. J. Environ. Anal. Chem., 26, 157-166 (1986).
J.-L. Veuthey, A. Deom, W. Haerdi, Plomb Sanguin et Atmosphérique dans le canton de Genève, Rev. Méd. Suisse Romande, 104, 1005-1012 (1984).

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