2021 |
| Double-PEGylated Cyclopeptidic Photosensitizer Prodrug Improves Drug Uptake from In Vitro to Hen's Egg Chorioallantoic Membrane Model Bouilloux, J. Kiening, M. Yapi, S. Lange, N. Molecules 2021 DOI: 10.3390/molecules26206241 |
2020 |
| Cathepsin B-Cleavable Cyclopeptidic Chemotherapeutic Prodrugs Herceg, V. Bouilloux, J. Janikowska, K. Allemann, E. Lange, N. Molecules 2020 DOI: 10.3390/molecules25184285 |
| c(RGDfK)- and ZnTriMPyP-Bound Polymeric Nanocarriers for Tumor-Targeted Photodynamic Therapy de las Heras, E. Boix-Garriga, E. Bryden, F. Agut, M. Mora, M. Sagrista, M. L. Boyle, R. W. Lange, N. Nonell, S. Photochemistry and Photobiology 2020 DOI: 10.1111/php.13238 |
2019 |
| The Dark Side: Photosensitizer Prodrugs Sansaloni-Pastor, S. Bouilloux, J. Lange, N. Pharmaceuticals 2019 DOI: 10.3390/ph12040148 |
| Squalene-PEG: Pyropheophorbide-a nanoconstructs for tumor theranostics Adriouach, S. Vorobiev, V. Trefalt, G. Allemann, E. Lange, N. Babic, A. Nanomedicine-Nanotechnology Biology and Medicine 2019 DOI: 10.1016/j.nano.2018.09.013 |
| Correction: Cyclopeptidic photosensitizer prodrugs as proteolytically triggered drug delivery systems of pheophorbide A: part II - co-loading of pheophorbide A and black hole quencher Bouilloux, J. Yushchenko, O. Dereka, B. Boso, G. Babic, A. Zbinden, H. Vauthey, E. Lange, N. Photochem Photobiol Sci 2019 DOI: 10.1039/c9pp90053e |
| Correction: Cyclopeptidic photosensitizer prodrugs as proteolytically triggered drug delivery systems of pheophorbide A: part I - self-quenched prodrugs Bouilloux, J. Yushchenko, O. Dereka, B. Boso, G. Zbinden, H. Vauthey, E. Babic, A. Lange, N. Photochem Photobiol Sci 2019 DOI: 10.1039/c9pp90052g |
2018 |
| Cyclopeptidic photosensitizer prodrugs as proteolytically triggered drug delivery systems of pheophorbide A: part I - self-quenched prodrugs Bouilloux, J. Yuschenko, O. Dereka, B. Boso, G. Zbinden, H. Vauthey, E. Babic, A. Lange, N. Photochemical & Photobiological Sciences 2018 DOI: 10.1039/c8pp00317c |
| Cyclopeptidic photosensitizer prodrugs as proteolytically triggered drug delivery systems of pheophorbide A: part II - co-loading of pheophorbide A and black hole quencher Bouilloux, J. Yuschenko, O. Dereka, B. Boso, G. Babic, A. Zbinden, H. Vauthey, E. Lange, N. Photochemical & Photobiological Sciences 2018 DOI: 10.1039/c8pp00318a |
| Squalene-PEG-Exendin as High-Affinity Constructs for Pancreatic Beta-Cells Babic, A. Vinet, L. Chellakudam, V. Janikowska, K. Allemann, E. Lange, N. Bioconjugate Chemistry 2018 DOI: 10.1021/acs.bioconjchem.8b00186 |
| Design, synthesis and in vitro evaluation of beta-glucuronidase-sensitive prodrug of 5-aminolevulinic acid for photodiagnosis of breast cancer cells Herceg, V. Adriouach, S. Janikowska, K. Allemann, E. Lange, N. Babic, A. Bioorganic Chemistry 2018 DOI: 10.1016/j.bioorg.2018.03.020 |
| Enzyme-mediated photoinactivation of Enterococcus faecalis using Rose Bengal-acetate Manoil, D. Lange, N. Bouillaguet, S. Journal of Photochemistry and Photobiology B-Biology 2018 DOI: 10.1016/j.jphotobiol.2018.01.001 |
| 5-Aminolevulinic Acid-Squalene Nanoassemblies for Tumor Photodetection and Therapy: In Vitro Studies Babic, A. Herceg, V. Bastien, E. Lassalle, H. P. Bezdetnaya, L. Lange, N. Nanoscale Research Letters 2018 DOI: 10.1186/s11671-017-2408-y |
2017 |
| An Activatable Photosensitizer Targeted to gamma-Glutamyltranspeptidase Chiba, M. Ichikawa, Y. Kamiya, M. Komatsu, T. Ueno, T. Hanaoka, K. Nagano, T. Lange, N. Urano, Y. Angewandte Chemie-International Edition 2017 DOI: 10.1002/anie.201704793 |
| Activity of phosphatase-sensitive 5-aminolevulinic acid prodrugs in cancer cell lines Herceg, V. Lange, N. Allemann, E. Babic, A. Journal of Photochemistry and Photobiology B-Biology 2017 DOI: 10.1016/j.jphotobiol.2017.04.029 |
2016 |
| Multivalent glibenclamide to generate islet specific imaging probes Babic, A. Lamprianou, S. Vinet, L. Stransky-Heilkron, N. Xayaphoummine, C. Campo, M. A. Glombik, H. Schulte, A. Juretschke, H. P. Montet, X. Meda, P. Lange, N. Biomaterials 2016 DOI: 10.1016/j.biomaterials.2015.10.006 |
| Tunable phosphatase-sensitive stable prodrugs of 5-aminolevulinic acid for tumor fluorescence photodetection Babic, A. Herceg, V. Ateb, I. Allemann, E. Lange, N. Journal of Controlled Release 2016 DOI: 10.1016/j.jconrel.2016.05.047 |
| Time-resolved singlet-oxygen luminescence detection with an efficient and practical semiconductor single-photon detector Boso, G. Ke, D. M. Korzh, B. Bouilloux, J. Lange, N. Zbinden, H. Biomedical Optics Express 2016 DOI: 10.1364/boe.7.000211 |
2015 |
| In vitro imaging of GLP-1R as an approach to non-invasive in vivo pancreatic islet imaging Chellakudam, V. Janikowska, K. Babic, A. Allemann, E. Lange, N. Diabetologia 2015 DOI: |
| Targeting GLP-1 receptors for repeated magnetic resonance imaging differentiates graded losses of pancreatic beta cells in mice Vinet, L. Lamprianou, S. Babic, A. Lange, N. Thorel, F. Herrera, P. L. Montet, X. Meda, P. Diabetologia 2015 DOI: 10.1007/s00125-014-3442-2 |
2014 |
| Protoporphyrin (PPIX) efflux by the MacAB-TolC pump in Escherichia coli Turlin, E. Heuck, G. Brandeo, M. I. S. Szili, N. Mellin, J. R. Lange, N. Wandersman, C. Microbiologyopen 2014 DOI: 10.1002/mbo3.203 |
| Flow cytometric assessment of Streptococcus mutans viability after exposure to blue light-activated curcumin Manoil, D. Filieri, A. Gameiro, C. Lange, N. Schrenzel, J. Wataha, J. C. Bouillaguet, S. Photodiagnosis and Photodynamic Therapy 2014 DOI: 10.1016/j.pdpdt.2014.06.003 |
| Antimicrobial Activity and Cytotoxicity of 3 Photosensitizers Activated with Blue Light Bulit, F. Grad, I. Manoil, D. Simon, S. Wataha, J. C. Filieri, A. Feki, A. Schrenzel, J. Lange, N. Bouillaguet, S. Journal of Endodontics 2014 DOI: 10.1016/j.joen.2013.12.001 |
2013 |
| Blue light-mediated inactivation of Enterococcus faecalis in vitro Pileggi, G. Wataha, J. C. Girard, M. Grad, I. Schrenzel, J. Lange, N. Bouillaguet, S. Photodiagnosis and Photodynamic Therapy 2013 DOI: 10.1016/j.pdpdt.2012.11.002 |
| Selective Photodetection and Photodynamic Therapy for Prostate Cancer through Targeting of Proteolytic Activity Zuluaga, M. F. Sekkat, N. Gabriel, D. van den Bergh, H. Lange, N. Molecular Cancer Therapeutics 2013 DOI: 10.1158/1535-7163.Mct-12-0780 |
2012 |
| Pharmaceutical technology at the service of targeted drug delivery Allemann, E. Delie, F. Lange, N. Chimia (Aarau) 2012 DOI: 10.2533/chimia.2012.308 |
| Thrombin-sensitive dual fluorescence imaging and therapeutic agent for detection and treatment of synovial inflammation in murine rheumatoid arthritis Gabriel, D. Lange, N. Chobaz-Peclat, V. Zuluaga, M. F. Gurny, R. van den Bergh, H. Busso, N. Journal of Controlled Release 2012 DOI: 10.1016/j.jconrel.2012.08.022 |
| Matrix mediated fluorescence enhancement - why nano-particles and PPIX make a friendly couple Heuck, G. Lange, N. Journal of Porphyrins and Phthalocyanines 2012 DOI: 10.1142/s1088424612500873 |
| Enhanced Prostate Cancer Targeting by Modified Protease Sensitive Photosensitizer Prodrugs Zuluaga, M. F. Gabriel, D. Lange, N. Molecular Pharmaceutics 2012 DOI: 10.1021/mp2005774 |
| Like a Bolt from the Blue: Phthalocyanines in Biomedical Optics Sekkat, N. van den Bergh, H. Nyokong, T. Lange, N. Molecules 2012 DOI: 10.3390/molecules17010098 |
2011 |
| It is All About Proteases: From Drug Delivery to In Vivo Imaging and Photomedicine Gabriel, D. Zuluaga, M. F. van den Bergh, H. Gurny, R. Lange, N. Current Medicinal Chemistry 2011 DOI: 10.2174/092986711795496782 |
| On the cutting edge: protease-sensitive prodrugs for the delivery of photoactive compounds Gabriel, D. Zuluaga, M. F. Lange, N. Photochemical & Photobiological Sciences 2011 DOI: 10.1039/c0pp00341g |
2010 |
| Production of Reactive Oxygen Species from Photosensitizers Activated with Visible Light Sources Available in Dental Offices Bouillaguet, S. Wataha, J. C. Zapata, O. Campo, M. Lange, N. Schrenzel, J. Photomedicine and Laser Surgery 2010 DOI: 10.1089/pho.2009.2505 |
| Benefit of anti-HER2-coated paclitaxel-loaded immuno-nanoparticles in the treatment of disseminated ovarian cancer: Therapeutic efficacy and biodistribution in mice Cirstoiu-Hapca, A. Buchegger, F. Lange, N. Bossy, L. Gurny, R. Delie, F. Journal of Controlled Release 2010 DOI: 10.1016/j.jconrel.2010.02.026 |
2009 |
| 5-ALA derivative-mediated photoinactivation of Propionibacterium acnes Fotinos, N. Mikulic, J. Convert, M. Campo, M. A. Piffaretti, J. C. Gurny, R. Lange, N. Journal of Dermatological Science 2009 DOI: 10.1016/j.jdermsci.2009.07.010 |
| Thrombin-sensitive photodynamic agents: A novel strategy for selective synovectomy in rheumatoid arthritis Gabriel, D. Busso, N. So, A. van den Bergh, H. Gurny, R. Lange, N. Journal of Controlled Release 2009 DOI: 10.1016/j.jconrel.2009.05.012 |
| Toward the understanding of the photodynamic activity of m-THPP encapsulated in PLGA nanoparticles: correlation between nanoparticle properties and in vivo activity Vargas, A. Lange, N. Arvinte, T. Cerny, R. Gurny, R. Delie, F. Journal of Drug Targeting 2009 DOI: 10.1080/10611860903118914 |
| Quenching-induced deactivation of photosensitizer by nano encapsulation to improve phototherapy of cancer Zeisser-Labouebe, M. Mattiuzzo, M. Lange, N. Gurny, R. Delie, F. Journal of Drug Targeting 2009 DOI: 10.1080/10611860903118930 |
| Bacteria capture iron from heme by keeping tetrapyrrol skeleton intact Letoffe, S. Heuck, G. Delepelaire, P. Lange, N. Wandersman, C. Proceedings of the National Academy of Sciences of the United States of America 2009 DOI: 10.1073/pnas.0903842106 |
| Benefits of nanoencapsulation for the hypercin-mediated photodetection of ovarian micrometastases Zeisser-Labouebe, M. Delie, F. Gurny, R. Lange, N. European Journal of Pharmaceutics and Biopharmaceutics 2009 DOI: 10.1016/j.ejpb.2008.10.005 |
| Screening of nanoparticulate delivery systems for the photodetection of cancer in a simple and cost-effective model Zeisser-Labouebe, M. Delie, F. Gurny, R. Lange, N. Nanomedicine 2009 DOI: 10.2217/17435889.4.2.135 |
| Urokinase-plasminogen-activator sensitive polymeric photosensitizer prodrugs: design, synthesis and in vitro evaluation Gabriel, D. Zuluaga, M. F. Martinez, M. N. Campo, M. A. Lange, N. Journal of Drug Delivery Science and Technology 2009 DOI: 10.1016/s1773-2247(09)50002-0 |
2008 |
| Simultaneous but not prior inhibition of VEGF165 enhances the efficacy of photodynamic therapy in multiple models of ocular neovascularization Ju, M. Mailhos, C. Bradley, J. Dowie, T. Ganley, M. Cook, G. Calias, P. Lange, N. Adamis, A. P. Shima, D. T. Robinson, G. S. Invest Ophthalmol Vis Sci 2008 DOI: 10.1167/iovs.07-0195 |
| Effects on gram-negative and gram-positive bacteria mediated by 5-aminolevulinic Acid and 5-aminolevulinic acid derivatives Fotinos, N. Convert, M. Piffaretti, J. C. Gurny, R. Lange, N. Antimicrob Agents Chemother 2008 DOI: 10.1128/AAC.01372-07 |
| Comparison of ALA- and ALA hexyl-ester-induced PpIX depth distribution in human skin carcinoma Dognitz, N. Salomon, D. Zellweger, M. Ballini, J. P. Gabrecht, T. Lange, N. van den Bergh, H. Wagnieres, G. Journal of Photochemistry and Photobiology B-Biology 2008 DOI: 10.1016/j.jphotobiol.2008.07.012 |
| Analysis of differential PDT effect in rat bladder tumor models according to concentrations of intravesical hexyl-aminolevulinate Berrahmoune, S. Fotinos, N. Bezdetnaya, L. Lange, N. Guedenet, J. C. Guillemin, F. D'Hallewin, M. A. Photochemical & Photobiological Sciences 2008 DOI: 10.1039/b804921a |
| Video monitoring of neovessel occlusion induced by photodynamic therapy with verteporfin (Visudyne (R)), in the CAM model Debefve, E. Pegaz, B. van den Bergh, H. Wagnieres, G. Lange, N. Ballini, J. P. Angiogenesis 2008 DOI: 10.1007/s10456-008-9106-4 |
| Intracellular reactive oxygen species in monocytes generated by photosensitive chromophores activated with blue light Bouillaguet, S. Owen, B. Wataha, J. C. Campo, M. A. Lange, N. Schrenzel, J. Dental Materials 2008 DOI: 10.1016/j.dental.2007.12.004 |
| Thermosetting gel for the delivery of 5-aminolevulinic acid esters to the cervix Collaud, S. Peng, Q. A. Gurny, R. Lange, N. Journal of Pharmaceutical Sciences 2008 DOI: 10.1002/jps.21181 |
| Molecular imaging in a (pre-) clinical context Lange, N. Becker, C. D. Montet, X. Acta Gastro-Enterologica Belgica 2008 DOI: |
| Combination of photodynamic therapy with anti-cancer agents Zuluaga, M. F. Lange, N. Current Medicinal Chemistry 2008 DOI: 10.2174/092986708784872401 |
2007 |
| Clinical evaluation of bioadhesive hydrogels for topical delivery of hexylaminolevulinate to Barrett's esophagus Collaud, S. Warloe, T. Jordan, O. Gurny, R. Lange, N. J Control Release 2007 DOI: 10.1016/j.jconrel.2007.08.015 |
| The chick embryo and its chorioallantoic membrane (CAM) for the in vivo evaluation of drug delivery systems Vargas, A. Zeisser-Labouebe, M. Lange, N. Gurny, R. Delie, F. Adv Drug Deliv Rev 2007 DOI: 10.1016/j.addr.2007.04.019 |
| Polymeric photosensitizer prodrugs for photodynamic therapy Campo, M. A. Gabriel, D. Kucera, P. Gurny, R. Lange, N. Photochem Photobiol 2007 DOI: 10.1111/j.1751-1097.2007.00090.x |
| Tailoring protease-sensitive photodynamic agents to specific disease-associated enzymes Gabriel, D. Campo, M. A. Gurny, R. Lange, N. Bioconjug Chem 2007 DOI: 10.1021/bc060321l |
| Synergies of VEGF inhibition and photodynamic therapy in the treatment of age-related macular degeneration Zuluaga, M. F. Mailhos, C. Robinson, G. Shima, D. T. Gurny, R. Lange, N. Invest Ophthalmol Vis Sci 2007 DOI: 10.1167/iovs.06-1224 |
| Hexyl-aminolevulinate-mediated photodynamic therapy: how to spare normal urothelium. An in vitro approach Vaucher, L. Jichlinski, P. Lange, N. Ritter-Schenk, C. van den Bergh, H. Kucera, P. Lasers Surg Med 2007 DOI: 10.1002/lsm.20416 |
2006 |
| Hypericin-loaded nanoparticles for the photodynamic treatment of ovarian cancer Zeisser-Labouebe, M. Lange, N. Gurny, R. Delie, F. Int J Pharm 2006 DOI: 10.1016/j.ijpharm.2006.07.012 |
| An open pharmacokinetic study of hexylaminolevulinate-induced photodiagnosis after intravesical administration Collaud, S. Jichlinski, P. Marti, A. Aymon, D. Gurny, R. Lange, N. Drugs R D 2006 DOI: 10.2165/00126839-200607030-00005 |
| Fluorescence diagnosis using enzyme-related metabolic abnormalities of neoplasia Campo, M. A. Lange, N. J Environ Pathol Toxicol Oncol 2006 DOI: 10.1615/jenvironpatholtoxicoloncol.v25.i1-2.220 |
| 5-Aminolevulinic acid derivatives in photomedicine: Characteristics, application and perspectives Fotinos, N. Campo, M. A. Popowycz, F. Gurny, R. Lange, N. Photochem Photobiol 2006 DOI: 10.1562/2006-02-03-IR-794 |
2005 |
| mitoKATP channel activation in the postanoxic developing heart protects E-C coupling via NO-, ROS-, and PKC-dependent pathways Sarre, A. Lange, N. Kucera, P. Raddatz, E. Am J Physiol Heart Circ Physiol 2005 DOI: 10.1152/ajpheart.00942.2004 |
2004 |
| In vitro metabolism of 5-ALA esters derivatives in hairless mice skin homogenate and in vivo PpIX accumulation studies De Rosa, F. S. Lopez, R. F. Thomazine, J. A. Tedesco, A. C. Lange, N. Bentley, M. V. Pharm Res 2004 DOI: 10.1007/s11095-004-7677-3 |
| Improved photodynamic activity of porphyrin loaded into nanoparticles: an in vivo evaluation using chick embryos Vargas, A. Pegaz, B. Debefve, E. Konan-Kouakou, Y. Lange, N. Ballini, J. P. van den Bergh, H. Gurny, R. Delie, F. Int J Pharm 2004 DOI: 10.1016/j.ijpharm.2004.07.029 |
| On the selectivity of 5-aminolevulinic acid-induced protoporphyrin IX formation Collaud, S. Juzeniene, A. Moan, J. Lange, N. Curr Med Chem Anticancer Agents 2004 DOI: 10.2174/1568011043352984 |
| Photodynamic therapy of skin cancer: controlled drug delivery of 5-ALA and its esters Lopez, R. F. Lange, N. Guy, R. Bentley, M. V. Adv Drug Deliv Rev 2004 DOI: 10.1016/j.addr.2003.09.002 |
2003 |
| Endoscopic fluorescence detection of intraepithelial neoplasia in Barrett's esophagus after oral administration of aminolevulinic acid Stepinac, T. Felley, C. Jornod, P. Lange, N. Gabrecht, T. Fontolliet, C. Grosjean, P. vanMelle, G. van den Bergh, H. Monnier, P. Wagnieres, G. Dorta, G. Endoscopy 2003 DOI: 10.1055/s-2003-41514 |
| Comparison of aminolevulinic acid and hexylester aminolevulinate induced protoporphyrin IX distribution in human bladder cancer Marti, A. Jichlinski, P. Lange, N. Ballini, J. P. Guillou, L. Leisinger, H. J. Kucera, P. J Urol 2003 DOI: 10.1097/01.ju.0000075054.38441.2d |
| Hexyl aminolevulinate fluorescence cystoscopy: new diagnostic tool for photodiagnosis of superficial bladder cancer--a multicenter study Jichlinski, P. Guillou, L. Karlsen, S. J. Malmstrom, P. U. Jocham, D. Brennhovd, B. Johansson, E. Gartner, T. Lange, N. van den Bergh, H. Leisinger, H. J. J Urol 2003 DOI: 10.1097/01.ju.0000060782.52358.04 |
| Photodynamic diagnosis of ovarian cancer using hexaminolaevulinate: a preclinical study Ludicke, F. Gabrecht, T. Lange, N. Wagnieres, G. Van Den Bergh, H. Berclaz, L. Major, A. L. Br J Cancer 2003 DOI: 10.1038/sj.bjc.6600958 |
| In vitro skin permeation and retention of 5-aminolevulinic acid ester derivatives for photodynamic therapy De Rosa, F. S. Tedesco, A. C. Lopez, R. F. Pierre, M. B. Lange, N. Marchetti, J. M. Rotta, J. C. Bentley, M. V. J Control Release 2003 DOI: 10.1016/s0168-3659(03)00125-1 |
| Enhanced delivery of 5-aminolevulinic acid esters by iontophoresis in vitro Lopez, R. F. Bentley, M. V. Delgado-Charro, M. B. Salomon, D. van den Bergh, H. Lange, N. Guy, R. H. Photochem Photobiol 2003 DOI: 10.1562/0031-8655(2003)077<0304:edoaae>2.0.co;2 |
2002 |
| Production of protoporphyrin IX from 5-aminolevulinic acid and two of its esters in cells in vitro and tissues in vivo Juzeniene, A. Ma, L. W. Juzenas, P. Iani, V. Lange, N. Moan, J. Cell Mol Biol (Noisy-le-grand) 2002 DOI: |
| Protoporphyrin IX photodynamic therapy for synovitis Kirdaite, G. Lange, N. Busso, N. Van Den Bergh, H. Kucera, P. So, A. Arthritis Rheum 2002 DOI: 10.1002/art.10199 |
2001 |
| Routine experimental system for defining conditions used in photodynamic therapy and fluorescence photodetection of (non-) neoplastic epithelia Lange, N. Vaucher, L. Marti, A. Etter, A. L. Gerber, P. van Den Bergh, H. Jichlinski, P. Kucera, P. J Biomed Opt 2001 DOI: 10.1117/1.1352751 |
| A new drug-screening procedure for photosensitizing agents used in photodynamic therapy for CNV Lange, N. Ballini, J. P. Wagnieres, G. van den Bergh, H. Invest Ophthalmol Vis Sci 2001 DOI: |
2000 |
| 5-Aminolevulinic acid and its derivatives: physical chemical properties and protoporphyrin IX formation in cultured cells Uehlinger, P. Zellweger, M. Wagnieres, G. Juillerat-Jeanneret, L. van den Bergh, H. Lange, N. J Photochem Photobiol B 2000 DOI: 10.1016/s1011-1344(99)00159-1 |
1999 |
| Optimisation of the formation and distribution of protoporphyrin IX in the urothelium: an in vitro approach Marti, A. Lange, N. van den Bergh, H. Sedmera, D. Jichlinski, P. Kucera, P. J Urol 1999 DOI: |
| Photodetection of early human bladder cancer based on the fluorescence of 5-aminolaevulinic acid hexylester-induced protoporphyrin IX: a pilot study Lange, N. Jichlinski, P. Zellweger, M. Forrer, M. Marti, A. Guillou, L. Kucera, P. Wagnieres, G. van den Bergh, H. Br J Cancer 1999 DOI: 10.1038/sj.bjc.6690338 |