Molecular therapeutics delivery group
Publications
Publications
2020-now Enhancing Oral Delivery of Biologics: A Non-Competitive and Cross-Reactive Anti-Leptin Receptor Nanofitin Demonstrates a Gut-Crossing Capacity in an Ex Vivo Porcine Intestinal Model. Masloh S, Chevrel A, Culot M, Perrocheau A, Kalia YN, Frehel S, Gaussin R, Gosselet F, Huet S, Zeisser Labouebe M, Scapozza L. Finite sample corrections for average equivalence testing. Boulaguiem Y, Quartier J, Lapteva M, Kalia YN, Victoria-Feser MP, Guerrier S, Couturier DL. Enhanced topical paromomycin delivery for cutaneous leishmaniasis treatment: Passive and iontophoretic approaches. de Sá FAP, Andrade JFM, Miranda TC, Cunha-Filho M, Gelfuso GM, Lapteva M, Kalia YN, Gratieri T. Development of an ex vivo porcine skin model for the preclinical evaluation of subcutaneously injected biomacromolecules. Gou S, Lapteva M, Brusini R, Flegeau K, Bourdon F, Kaya G, Faivre J, Kalia YN. Polymeric micelles for cutaneous delivery of the hedgehog pathway inhibitor TAK-441: Formulation development and cutaneous biodistribution in porcine and human skin. Darade AR, Lapteva M, Ling V, Kalia YN. Injectable Hyaluronan-Based Thermoresponsive Hydrogels for Dermatological Applications. Gou S, Porcello A, Allémann E, Salomon D, Micheels P, Jordan O, Kalia YN. Influence of Molecular Structure and Physicochemical Properties of Immunosuppressive Drugs on Micelle Formulation Characteristics and Cutaneous Delivery. Quartier J, Lapteva M, Boulaguiem Y, Guerrier S, Kalia YN. Biodistribution of progesterone in the eye after topical ocular administration via drops or inserts. Alambiaga-Caravaca AM, González Iglesias LG, Rodilla V, Kalia YN, López-Castellano A. Bolus delivery of palonosetron through skin by tip-loaded dissolving microneedles with short-duration iontophoresis: A potential strategy to rapidly relieve emesis associated with chemotherapy. Kang D, Ge Q, Natabou MA, Xu W, Liu X, Xu B, Bao X, Kalia YN, Chen Y. Erbium:YAG fractional laser ablation improves cutaneous delivery of pentoxifylline from different topical dosage forms. Gou S, Del Río-Sancho S, Laubach HJ, Kalia YN. Non-Invasive Iontophoretic Delivery of Cytochrome c to the Posterior Segment and Determination of Its Ocular Biodistribution. González Iglesias LG, Messaoudi S, Kalia YN. Simultaneous Delivery of Econazole, Terbinafine and Amorolfine with Improved Cutaneous Bioavailability: A Novel Micelle-Based Antifungal "Tri-Therapy". Gou S, Monod M, Salomon D, Kalia YN. Effect of mRNA Delivery Modality and Formulation on Cutaneous mRNA Distribution and Downstream eGFP Expression. Darade AR, Lapteva M, Hoffmann T, Mandler M, Schneeberger A, Kalia YN. Preclinical and clinical studies to evaluate cutaneous biodistribution, safety and efficacy of UV filters encapsulated in mesoporous silica SBA-15. Daneluti ALM, Guerra LO, Velasco MVR, do Rosário Matos J, Baby AR, Kalia YN. Using Porcine Jejunum Ex Vivo to Study Absorption and Biotransformation of Natural Products in Plant Extracts: Pueraria lobata as a Case Study. Houriet J, Arnold YE, Pellissier L, Kalia YN, Wolfender JL. Controlled simultaneous iontophoresis of buflomedil hydrochloride and dexamethasone sodium phosphate to the mucosa for oral submucous fibrosis. Tyagi V, Serna-Jiménez CE, Kalia YN. DESI-MS imaging to visualize spatial distribution of xenobiotics and endogenous lipids in the skin. Quartier J, Rao W, Slade S, Métral F, Lapteva M, Kalia YN. Current profile controlled transdermal delivery of pramipexole from an iontophoretic patch system in vitro and in vivo. Singhal M, Serna C, Merino V, Kalia YN. Polymeric micelle mediated follicular delivery of spironolactone: Targeting the mineralocorticoid receptor to prevent glucocorticoid-induced activation and delayed cutaneous wound healing. Dahmana N, Mugnier T, Gabriel D, Favez T, Kowalczuk L, Behar-Cohen F, Gurny R, Kalia YN. Polymeric micelle formulations for the cutaneous delivery of sirolimus: A new approach for the treatment of facial angiofibromas in tuberous sclerosis complex. Quartier J, Lapteva M, Boulaguiem Y, Guerrier S, Kalia YN. Microemulsion-based gel for the transdermal delivery of rasagiline mesylate: In vitro and in vivo assessment for Parkinson's therapy. Patel P, Pol A, Kalaria D, Date AA, Kalia Y, Patravale V. The influence of skin barrier impairment on the iontophoretic transport of low and high molecular weight permeants. Gratieri T, Zarhloule R, Dubey S, Kalia YN. Effect of continuous and multi-phasic current profiles on the iontophoretic transport of pramipexole, rasagiline and huperzine A: Depicting temporal variation and biodistribution in the skin. Singhal M, Serna C, Kalaria D, Kalia YN. Co-administration of zinc phthalocyanine and quercetin via hybrid nanoparticles for augmented photodynamic therapy. Thakur NS, Mandal N, Patel G, Kirar S, Reddy YN, Kushwah V, Jain S, Kalia YN, Bhaumik J, Banerjee UC. Iontosomes: Electroresponsive Liposomes for Topical Iontophoretic Delivery of Chemotherapeutics to the Buccal Mucosa. Sonaje K, Tyagi V, Chen Y, Kalia YN. Using protease inhibitors to improve protein stability in the presence of skin: A case study on the stability of insulin like growth factor 1. Dubey S, Perozzo R, Scapozza L, Kalia YN. Specific protein-protein interactions limit the cutaneous iontophoretic transport of interferon beta-1b and a poly-Arg interferon beta-1b analogue. Dubey S, Perozzo R, Scapozza L, Kalia YN. Using Ex Vivo Porcine Jejunum to Identify Membrane Transporter Substrates: A Screening Tool for Early-Stage Drug Development. Arnold YE, Kalia YN. Tissue Levels of Flurbiprofen in the Rat Plantar Heel after Short-Duration Topical Iontophoresis are Sufficient to Induce Pharmacodynamic Responses to Local Pain Stimuli. Cai Y, Zhou Y, Zhang P, Kalia YN, Gratieri T, Chen Y Targeted cutaneous delivery of etanercept using Er:YAG fractional laser ablation Del Río-Sancho S, Lapteva M, Sonaje K, Böhler C, Ling V, Boehncke WH, Kalia YN. Non-invasive targeted iontophoretic delivery of cetuximab to skin. Lapteva M, Sallam MA, Goyon A, Guillarme D, Veuthey JL, Kalia YN. 2015-2019 Ocular Biodistribution of Spironolactone after a Single Intravitreal Injection of a Biodegradable Sustained-Release Polymer in Rats. Dahmana N, Kowalczuk L, Gabriel D, Behar-Cohen F, Gurny R, Kalia YN. Cutaneous Biodistribution: A High-Resolution Methodology to Assess Bioequivalence in Topical Skin Delivery. Quartier J, Capony N, Lapteva M, Kalia YN. Topical iontophoresis of buflomedil hydrochloride increases drug bioavailability in the mucosa: A targeted approach to treat oral submucous fibrosis. Tyagi V, Sancho SD, Lapteva M, Kalia YN. Controlled Iontophoretic Delivery in Vitro and in Vivo of ARN14140-A Multitarget Compound for Alzheimer's Disease. Singhal M, Merino V, Rosini M, Cavalli A, Kalia YN. Er:YAG fractional laser ablation for cutaneous co-delivery of pentoxifylline and d-α-tocopherol succinate: A new approach for topical treatment of radiation-induced skin fibrosis. Gou S, Del Rio-Sancho S, Singhal M, Laubach HJ, Kalia YN. Polymeric micelle nanocarriers for targeted epidermal delivery of the hedgehog pathway inhibitor vismodegib: formulation development and cutaneous biodistribution in human skin. Kandekar SG, Singhal M, Sonaje KB, Kalia YN. Drug Transport across Porcine Intestine Using an Ussing Chamber System: Regional Differences and the Effect of P-Glycoprotein and CYP3A4 Activity on Drug Absorption. Arnold YE, Thorens J, Bernard S, Kalia YN. Fractional laser ablation for the targeted cutaneous delivery of an anti-CD29 monoclonal antibody - OS2966. Lapteva M, Del Río-Sancho S, Wu E, Carbonell WS, Böhler C, Kalia YN. Self-assembled mPEG-hexPLA polymeric nanocarriers for the targeted cutaneous delivery of imiquimod. Lapteva M, Mignot M, Mondon K, Möller M, Gurny R, Kalia YN. Investigation of Different Iontophoretic Currents Profiles for Short-Term Applications in Cosmetics. Cázares-Delgadillo J, Planard-Luong L, Gregoire S, Serna-Jiménez CE, Singhal M, Kalia YN, Merino V, Merino-Sanjuán M, Nácher A, Martínez-Gómez MA, Burnier-Yalaoui V, Barbarat P. Strategies for modifying drug residence time and ocular bioavailability to decrease treatment frequency for back of the eye diseases. Shatz W, Aaronson J, Yohe S, Kelley RF, Kalia YN. Controlled non-invasive iontophoretic delivery of triamcinolone acetonide amino acid ester prodrugs into the posterior segment of the eye. Santer V, Chen Y, Kalia YN. Hydrogels in three-dimensional dendritic cell (MUTZ-3) culture as a scaffold to mimic human immuno competent subcutaneous tissue. Groell F, Kalia YN, Jordan O, Borchard G. Hyaluronic Acid After Subcutaneous Injection-An Objective Assessment. Santer V, Molliard SG, Micheels P, Río-Sancho SD, Quinodoz P, Kalia YN, Salomon D. Needle-free cutaneous delivery of living human cells by Er:YAG fractional laser ablation. Yu J, Dubey S, Kalia YN Development and validation of a fast and sensitive UHPLC-ESI-MS method for the simultaneous quantification of spironolactone and its metabolites in ocular tissues Dahmana N, Gabriel D, Gurny R, Kalia YN Topical Administration of Spironolactone-Loaded Nanomicelles Prevents Glucocorticoid-Induced Delayed Corneal Wound Healing in Rabbits. Dahmana N, Mugnier T, Gabriel D, Kaltsatos V, Bertaim T, Behar-Cohen F, Gurny R, Kalia YN. Simultaneous controlled iontophoretic delivery of pramipexole and rasagiline in vitro and in vivo: Transdermal polypharmacy to treat Parkinson's Disease. Kalaria DR, Singhal M, Patravale V, Merino V, Kalia YN. Selective delivery of adapalene to the human hair follicle under finite dose conditions using polymeric micelle nanocarriers. Kandekar SG , Del Río-Sancho S , Lapteva M , Kalia YN . Short-duration ocular iontophoresis of ionizable aciclovir prodrugs: A new approach to treat herpes simplex infections in the anterior and posterior segments of the eye. Chen Y, Kalia YN. Targeted intracorneal delivery-Biodistribution of triamcinolone acetonide following topical iontophoresis of cationic amino acid ester prodrugs. Santer V, Del Río Sancho S, Lapteva M, Kalia YN. Formulation challenges for 21st century topical and transdermal delivery systems. Singhal M, Lapteva M, Kalia YN. Cutaneous iontophoresis of μ-conotoxin CnIIIC-A potent NaV1.4 antagonist with analgesic, anaesthetic and myorelaxant properties. Del Río-Sancho S, Cros C, Coutaz B, Cuendet M, Kalia YN. Transdermal therapeutic systems for memantine delivery. Comparison of passive and iontophoretic transport. Del Río-Sancho S, Serna-Jiménez CE, Sebastián-Morelló M, Calatayud-Pascual MA, Balaguer-Fernández C, Femenía-Font A, Kalia YN, Merino V, López-Castellano A. Basic principles and current status of transcorneal and transscleral iontophoresis. Gratieri T, Santer V, Kalia YN. Topical delivery of diclofenac into and across equine skin from a novel liquid diclofenac epolamine formulation. Del Río-Sancho S, Concas D, Oreste P, Zoppetti G, Briggs PH, Kalia YN. Improved topical delivery of tacrolimus: A novel composite hydrogel formulation for the treatment of psoriasis. Gabriel D, Mugnier T, Courthion H, Kranidioti K, Karagianni N, Denis MC, Lapteva M, Kalia Y, Möller M, Gurny R. Erratum to Chen Y, Alberti I, Kalia YN. A UHPLC-UV Method to Quantify Skin Deposition and Transdermal Permeation of Tizanidine Hydrochloride. del Río-Sancho S, Merino V, López-Castellano A, Kalia YN. Controlled transdermal iontophoresis for poly-pharmacotherapy: Simultaneous delivery of granisetron, metoclopramide and dexamethasone sodium phosphate in vitro and in vivo. Cázares-Delgadillo J, Ganem-Rondero A, Merino V, Kalia YN. Fractional Laser Ablation for the Cutaneous Delivery of Triamcinolone Acetonide from Cryomilled Polymeric Microparticles: Creating Intraepidermal Drug Depots. Singhal M, Del Río-Sancho S, Sonaje K, Kalia YN. Topical iontophoretic delivery of ionizable, biolabile aciclovir prodrugs: A rational approach to improve cutaneous bioavailability. Chen Y, Alberti I, Kalia YN. Eur J Pharm Biopharm. 2016 Feb;99:103-13. doi: 10.1016/j.ejpb.2015.12.002. Epub 2015 Dec 11. Erratum in: Eur J Pharm Biopharm. 2016 May;102:19. Cutaneous biodistribution of ionizable, biolabile aciclovir prodrugs after short duration topical iontophoresis: Targeted intraepidermal drug delivery. Chen Y, Zahui T, Alberti I, Kalia YN. Self-assembled polymeric nanocarriers for the targeted delivery of retinoic acid to the hair follicle. Lapteva M, Möller M, Gurny R, Kalia YN. Synthesis of 3-azabicyclo[3.2.2]nonanes and their antiprotozoal activities. Seebacher W, Wolkinger V, Faist J, Kaiser M, Brun R, Saf R, Bucar F, Gröblacher B, Brantner A, Merino V, Kalia Y, Scapozza L, Perozzo R, Weis R. Transdermal patches: history, development and pharmacology. Pastore MN, Kalia YN, Horstmann M, Roberts MS. 2010-2014 Targeted cutaneous delivery of ciclosporin A using micellar nanocarriers and the possible role of inter-cluster regions as molecular transport pathways. Lapteva M, Santer V, Mondon K, Patmanidis I, Chiriano G, Scapozza L, Gurny R, Möller M, Kalia YN. Colloidal soft nanocarrier for transdermal delivery of dopamine agonist: ex vivo and in vivo evaluation. Patel P, Pol A, More S, Kalaria DR, Kalia YN, Patravale VB. Polymeric micelle nanocarriers for the cutaneous delivery of tacrolimus: a targeted approach for the treatment of psoriasis. Lapteva M, Mondon K, Möller M, Gurny R, Kalia YN. Understanding the poor iontophoretic transport of lysozyme across the skin: when high charge and high electrophoretic mobility are not enough. Dubey S, Kalia YN. Controlled iontophoretic delivery of pramipexole: electrotransport kinetics in vitro and in vivo. Kalaria DR, Patel P, Merino V, Patravale VB, Kalia YN. Targeted local simultaneous iontophoresis of chemotherapeutics for topical therapy of head and neck cancers. Gratieri T, Kalia YN. Controlled iontophoretic transport of huperzine A across skin in vitro and in vivo: effect of delivery conditions and comparison of pharmacokinetic models. Kalaria DR, Patel P, Merino V, Patravale VB, Kalia YN. Turning theory into practice: the development of modern transdermal drug delivery systems and future trends. Perumal O, Murthy SN, Kalia YN. Iontophoretic transport kinetics of ketorolac in vitro and in vivo: demonstrating local enhanced topical drug delivery to muscle. Gratieri T, Pujol-Bello E, Gelfuso GM, de Souza JG, Lopez RF, Kalia YN. Microstructured bicontinuous phase formulations: their characterization and application in dermal and transdermal drug delivery. Lapteva M, Kalia YN. Next generation intra- and transdermal therapeutic systems: using non- and minimally-invasive technologies to increase drug delivery into and across the skin. Gratieri T, Alberti I, Lapteva M, Kalia YN. Comparative in vitro and in vivo evaluation of lipid based nanocarriers of Huperzine A. Patel PA, Patil SC, Kalaria DR, Kalia YN, Patravale VB. Controlled intra- and transdermal protein delivery using a minimally invasive Erbium:YAG fractional laser ablation technology. Bachhav YG, Heinrich A, Kalia YN. Mathematical models to describe iontophoretic transport in vitro and in vivo and the effect of current application on the skin barrier. Gratieri T, Kalia YN. Comparison of the cutaneous iontophoretic delivery of rasagiline and selegiline across porcine and human skin in vitro. Kalaria DR, Patel P, Patravale V, Kalia YN. The pharmaceutical biochemistry group: where pharmaceutical chemistry meets biology and drug delivery. Kalia YN, Perozzo R, Scapozza L. Transcutaneous vaccination via laser microporation. Weiss R, Hessenberger M, Kitzmüller S, Bach D, Weinberger EE, Krautgartner WD, Hauser-Kronberger C, Malissen B, Boehler C, Kalia YN, Thalhamer J, Scheiblhofer S. Development and validation of a HPAE-PAD method for the quantification of CGP69669A, a sialyl Lewis(x) mimetic, in skin permeation studies. Gratieri T, Wagner B, Kalaria D, Ernst B, Kalia YN. Cutaneous iontophoretic delivery of CGP69669A, a sialyl Lewis(x) mimetic, in vitro. Gratieri T, Wagner B, Kalaria D, Ernst B, Kalia YN. Erbium:YAG fractional laser ablation for the percutaneous delivery of intact functional therapeutic antibodies. Yu J, Kalaria DR, Kalia YN. Noninvasive transdermal iontophoretic delivery of biologically active human basic fibroblast growth factor. Dubey S, Perozzo R, Scapozza L, Kalia YN. Using controlled laser-microporation to increase transdermal delivery of prednisone. Yu J, Bachhav YG, Summer S, Heinrich A, Bragagna T, Böhler C, Kalia YN. Non-invasive iontophoretic delivery of peptides and proteins across the skin. Gratieri T, Kalaria D, Kalia YN. Using laser microporation to improve transdermal delivery of diclofenac: Increasing bioavailability and the range of therapeutic applications. Bachhav YG, Heinrich A, Kalia YN. Electrically-assisted delivery of an anionic protein across intact skin: cathodal iontophoresis of biologically active ribonuclease T1. Dubey S, Kalia YN. Novel micelle formulations to increase cutaneous bioavailability of azole antifungals. Bachhav YG, Mondon K, Kalia YN, Gurny R, Möller M. Human growth hormone: new delivery systems, alternative routes of administration, and their pharmacological relevance. Cázares-Delgadillo J, Ganem-Rondero A, Kalia YN. Development and validation of a rapid high-performance liquid chromatography method for the quantification of exenatide. Bachhav YG, Kalia YN. Effect of controlled laser microporation on drug transport kinetics into and across the skin. Bachhav YG, Summer S, Heinrich A, Bragagna T, Böhler C, Kalia YN. Comparing metoclopramide electrotransport kinetics in vitro and in vivo. Cázares-Delgadillo J, Aziza IB, Balaguer-Fernández C, Calatayud-Pascual A, Ganem-Rondero A, Quintanar-Guerrero D, Castellano AC, Merino V, Kalia YN. Non-invasive iontophoretic delivery of enzymatically active ribonuclease A (13.6 kDa) across intact porcine and human skins. Dubey S, Kalia YN. Transdermal iontophoresis of dexamethasone sodium phosphate in vitro and in vivo: effect of experimental parameters and skin type on drug stability and transport kinetics. Cázares-Delgadillo J, Balaguer-Fernández C, Calatayud-Pascual A, Ganem-Rondero A, Quintanar-Guerrero D, López-Castellano AC, Merino V, Kalia YN. Using transdermal iontophoresis to increase granisetron delivery across skin in vitro and in vivo: effect of experimental conditions and a comparison with other enhancement strategies. Cázares-Delgadillo J, Ganem-Rondero A, Quintanar-Guerrero D, López-Castellano AC, Merino V, Kalia YN. Development and validation of an analytical method for the quantification of cytochrome c in skin transport studies. Bachhav YG, Kalia YN. 2005-2009 Stability of triptorelin in the presence of dermis and epidermis. Bachhav YG, Kalia YN. Controlled non-invasive transdermal iontophoretic delivery of zolmitriptan hydrochloride in vitro and in vivo. Patel SR, Zhong H, Sharma A, Kalia YN. In vitro evaluation of the effect of electrotreatment on skin permeability. Marra F, Levy JL, Santi P, Kalia YN. In vivo methods for the assessment of topical drug bioavailability. Herkenne C, Alberti I, Naik A, Kalia YN, Mathy FX, Préat V, Guy RH. Effect of propylene glycol on ibuprofen absorption into human skin in vivo. Herkenne C, Naik A, Kalia YN, Hadgraft J, Guy RH. Transdermal delivery of cytochrome C--A 12.4 kDa protein--across intact skin by constant-current iontophoresis. Cázares-Delgadillo J, Naik A, Ganem-Rondero A, Quintanar-Guerrero D, Kalia YN. In vitro and in vivo evaluation of the transdermal iontophoretic delivery of sumatriptan succinate. Patel SR, Zhong H, Sharma A, Kalia YN. Dermatopharmacokinetic prediction of topical drug bioavailability in vivo. Herkenne C, Naik A, Kalia YN, Hadgraft J, Guy RH. Ibuprofen transport into and through skin from topical formulations: in vitro-in vivo comparison. Herkenne C, Naik A, Kalia YN, Hadgraft J, Guy RH. Applications of thermo-reversible pluronic F-127 gels in pharmaceutical formulations. Escobar-Chávez JJ, López-Cervantes M, Naïk A, Kalia YN, Quintanar-Guerrero D, Ganem-Quintanar A. Topical iontophoresis of valaciclovir hydrochloride improves cutaneous aciclovir delivery. Abla N, Naik A, Guy RH, Kalia YN. Pig ear skin ex vivo as a model for in vivo dermatopharmacokinetic studies in man. Herkenne C, Naik A, Kalia YN, Hadgraft J, Guy RH. Structure-permeation relationships for the non-invasive transdermal delivery of cationic peptides by iontophoresis. Schuetz YB, Carrupt PA, Naik A, Guy RH, Kalia YN. Emerging strategies for the transdermal delivery of peptide and protein drugs. Schuetz YB, Naik A, Guy RH, Kalia YN. Capillary zone electrophoresis for the estimation of transdermal iontophoretic mobility. Abla N, Geiser L, Mirgaldi M, Naik A, Veuthey JL, Guy RH, Kalia YN. Effect of charge and molecular weight on transdermal peptide delivery by iontophoresis. Abla N, Naik A, Guy RH, Kalia YN. Contributions of electromigration and electroosmosis to peptide iontophoresis across intact and impaired skin. Abla N, Naik A, Guy RH, Kalia YN. Effect of amino acid sequence on transdermal iontophoretic peptide delivery. Schuetz YB, Naik A, Guy RH, Kalia YN. Transdermal iontophoretic delivery of triptorelin in vitro. Schuetz YB, Naik A, Guy RH, Vuaridel E, Kalia YN. Transdermal iontophoretic delivery of vapreotide acetate across porcine skin in vitro. Schuetz YB, Naik A, Guy RH, Vuaridel E, Kalia YN. Skin permeation enhancement by sucrose esters: a pH-dependent phenomenon. Cázares-Delgadillo J, Naik A, Kalia YN, Quintanar-Guerrero D, Ganem-Quintanar A. 2000-2004 Enhancement of topical delivery from biodegradable nanoparticles. Alvarez-Román R, Naik A, Kalia YN, Guy RH, Fessi H. Development of an in vitro model for premature neonatal skin: biophysical characterization using transepidermal water loss. Sekkat N, Kalia YN, Guy RH. Porcine ear skin as a model for the assessment of transdermal drug delivery to premature neonates. Sekkat N, Kalia YN, Guy RH. Skin penetration and distribution of polymeric nanoparticles. Alvarez-Román R, Naik A, Kalia YN, Guy RH, Fessi H. Visualization of skin penetration using confocal laser scanning microscopy. Alvarez-Román R, Naik A, Kalia YN, Fessi H, Guy RH. Non-invasive assessment of the effect of formulation excipients on stratum corneum barrier function in vivo. Curdy C, Naik A, Kalia YN, Alberti I, Guy RH. Iontophoretic drug delivery. Kalia YN, Naik A, Garrison J, Guy RH. Effects of sucrose oleate and sucrose laureate on in vivo human stratum corneum permeability. Ayala-Bravo HA, Quintanar-Guerrero D, Naik A, Kalia YN, Cornejo-Bravo JM, Ganem-Quintanar A. Skin permeability enhancement by low frequency sonophoresis: lipid extraction and transport pathways. Alvarez-Román R, Merino G, Kalia YN, Naik A, Guy RH. Ultrasound-enhanced transdermal transport. Merino G, Kalia YN, Guy RH. Frequency and thermal effects on the enhancement of transdermal transport by sonophoresis. Merino G, Kalia YN, Delgado-Charro MB, Potts RO, Guy RH. Biophysical study of porcine ear skin in vitro and its comparison to human skin in vivo. Sekkat N, Kalia YN, Guy RH. Reverse iontophoretic monitoring in premature neonates: feasibility and potential. Sekkat N, Naik A, Kalia YN, Glikfeld P, Guy RH. In vivo assessment of skin electroporation using square wave pulses. Dujardin N, Staes E, Kalia Y, Clarys P, Guy R, Préat V. Post-iontophoresis recovery of human skin impedance in vivo. Curdy C, Kalia YN, Guy RH. Optimizing iontophoretic drug delivery: identification and distribution of the charge-carrying species. Marro D, Kalia YN, Delgado-Charro MB, Guy RH. Contributions of electromigration and electroosmosis to iontophoretic drug delivery. Marro D, Kalia YN, Delgado-Charro MB, Guy RH. Assessment and prediction of the cutaneous bioavailability of topical terbinafine, in vivo, in man. Alberti I, Kalia YN, Naik A, Guy RH. Piroxicam delivery into human stratum corneum in vivo: iontophoresis versus passive diffusion. Curdy C, Kalia YN, Naik A, Guy RH. Passive skin penetration enhancement and its quantification in vitro. Moser K, Kriwet K, Naik A, Kalia YN, Guy RH. Enhanced skin permeation of a lipophilic drug using supersaturated formulations. Moser K, Kriwet K, Kalia YN, Guy RH. Assessment of topical bioavailability in vivo: the importance of stratum corneum thickness. Kalia YN, Alberti I, Naik A, Guy RH. Iontophoretic transport across the skin. Guy RH, Delgado-Charro MB, Kalia YN. Supersaturation: enhancement of skin penetration and permeation of a lipophilic drug. Moser K, Kriwet K, Froehlich C, Kalia YN, Guy RH. Stabilization of supersaturated solutions of a lipophilic drug for dermal delivery. Moser K, Kriwet K, Kalia YN, Guy RH. Non-invasive assessment of the effects of iontophoresis on human skin in-vivo. Curdy C, Kalia YN, Guy RH. Modeling transdermal drug release. Kalia YN, Guy RH. Effect of ethanol and isopropyl myristate on the availability of topical terbinafine in human stratum corneum, in vivo. Alberti I, Kalia YN, Naik A, Bonny J, Guy RH. In vivo assessment of enhanced topical delivery of terbinafine to human stratum corneum. Alberti I, Kalia YN, Naik A, Bonny JD, Guy RH. Permeation enhancement of a highly lipophilic drug using supersaturated systems. Moser K, Kriwet K, Froehlich C, Naik A, Kalia YN, Guy RH. Factors and strategies for improving buccal absorption of peptides. Veuillez F, Kalia YN, Jacques Y, Deshusses J, Buri P. Recovery of human skin impedance in vivo after iontophoresis: effect of metal ions. Curdy C, Kalia YN, Falson-Rieg F, Guy RH. Normalization of stratum corneum barrier function and transepidermal water loss in vivo. Kalia YN, Alberti I, Sekkat N, Curdy C, Naik A, Guy RH. Transdermal drug delivery: overcoming the skin's barrier function. Naik A, Kalia YN, Guy RH. Transepidermal water loss in 24 and 25 weeks gestational age infants. Nonato LB, Lund CH, Kalia YN, Guy RH. Iontophoresis: electrorepulsion and electroosmosis. Guy RH, Kalia YN, Delgado-Charro MB, Merino V, López A, Marro D. 1995-1999 Electrorepulsion versus electroosmosis: effect of pH on the iontophoretic flux of 5-fluorouracil. Merino V, López A, Kalia YN, Guy RH. Ion mobility across human stratum corneum in vivo. Kalia YN, Pirot F, Potts RO, Guy RH. The effect of keratolytic agents on the permeability of three imidazole antimycotic drugs through the human nail. Quintanar-Guerrero D, Ganem-Quintanar A, Tapia-Olguín P, Kalia YN, Buri P. Development of skin barrier function in premature infants. Kalia YN, Nonato LB, Lund CH, Guy RH. Transdermal drug delivery. Clinical aspects. Kalia YN, Merino V, Guy RH. Stratum corneum thickness and apparent water diffusivity: facile and noninvasive quantitation in vivo. Pirot F, Berardesca E, Kalia YN, Singh M, Maibach HI, Guy RH. The effect of current on skin barrier function in vivo: recovery kinetics post-iontophoresis. Turner NG, Kalia YN, Guy RH. Transdermal therapy and diagnosis by iontophoresis. Merino V, Kalia YN, Guy RH. Characterization of the permeability barrier of human skin in vivo. Pirot F, Kalia YN, Stinchcomb AL, Keating G, Bunge A, Guy RH. Transdermal delivery of peptides by iontophoresis. Hirvonen J, Kalia YN, Guy RH. Homogeneous transport in a heterogeneous membrane: water diffusion across human stratum corneum in vivo. Kalia YN, Pirot F, Guy RH. The effect of iontophoresis on skin barrier integrity: non-invasive evaluation by impedance spectroscopy and transepidermal water loss. Kalia YN, Nonato LB, Guy RH. In vitro study of percutaneous absorption, cutaneous bioavailability and bioequivalence of zinc and copper from five topical formulations. Pirot F, Millet J, Kalia YN, Humbert P. The electrical characteristics of human skin in vivo. Kalia YN, Guy RH. Book Chapter Correlation between impedance spectroscopy and transepidermal water loss: non-invasive probes of human skin permeability in vivo. Y. N. Kalia, L. B. Nonato, R. H. Guy. In: K. R. Brain, V. J. James and K. A. Walters (eds.), Prediction of Percutaneous Penetration, Volume 4B, STS Publishing Ltd., Cardiff, pp.38-41, (1996). Characterization of molecular transport across human stratum corneum in vivo. A. Naik, Y. N. Kalia, F. Pirot, R. H. Guy. In: R. Bronaugh and H. I. Maibach (eds.), Percutaneous Absorption 3rd ed., Marcel Dekker, New York, pp. 149-175, (1999). The development of skin barrier function in the neonate. L. B. Nonato, Y. N. Kalia, A. Naik, C. H. Lund, R. H. Guy. In: R. Bronaugh and H. I. Maibach (eds.), Percutaneous Absorption 3rd ed., Marcel Dekker, New York, pp. 825-860, (1999). Characterization of molecular transport across human stratum corneum in vivo. A. Naik, Y. N. Kalia, F. Pirot, R. H. Guy. In: R. Bronaugh and H. I. Maibach (eds.), Percutaneous Absorption: Drugs-Cosmetics-Mechanisms-Methodology, Marcel Dekker, New York (2001). The development of skin barrier function in the neonate. L. B. Nonato, Y. N. Kalia, A. Naik, C. H. Lund, R. H. Guy. In: R. Bronaugh and H. I. Maibach (eds.), Percutaneous Absorption: Drugs-Cosmetics-Mechanisms-Methodology, Marcel Dekker, New York (2001). Iontophoresis: Clinical applications and future challenges N. Abla, A. Naik, R. H. Guy, Y. N. Kalia. In: E. Smith and H. I. Maibach (eds.), Percutaneous Penetration Enhancers – Volume 2, CRC Press, Boca Raton (2006), pp 177-219. Transdermic system with cosmetic efficiency. Y. N. Kalia, J.-L. Levy, F. Garcia Pérez. In: J.-L. Levy (ed.), The Secrets of Anti-aging, Arnette (2007), pp 129-149. Clinical applications of transdermal iontophoresis. D. R. Kalaria, S. Dubey, Y. N. Kalia. In: H. Benson and A. Watkinson (eds.), Topical and transdermal drug delivery, John Wiley & Sons, Inc. (2011), pp 67-83. Stratum corneum ablation techniques. S. Dubey, D. R. Kalaria, T. Gratieri, Y. N. Kalia. In: R. F. V. Lopez, T. Gratieri and G. M. Gelfuso (eds.), Physical methods to increase topical and transdermal drug delivery, Transworld Research Network (2012), pp 145-159. Iontophoretic delivery of glycomimetics - a new approach for the treatment of inflammatory skin diseases. T. Gratieri, B. Wagner, D. Kalaria, B. Ernst, Y. N. Kalia. In: R. Chilcott and K. Brain (eds.), Advances in dermatological sciences, RSC, (2013), pp. 178-188. Topical iontophoresis for targeted local drug delivery to the eye and skin. T. Gratieri, Y. N. Kalia. In: A.V. Domb (ed.), Advances in delivery science and technology – Focal controlled drug delivery, Springer, (2014), pp 263-284. Iontophoresis. T Gratieri, Y. N. Kalia. In: N. Dragicevic-Curic and H. I. Maibach (eds.), Percutaneous Penetration Enhancers – Springer, in press. Iontophoretic transport mechanisms and factors affecting electrically-assisted delivery. T Gratieri, Y. N. Kalia. In: N. Dragicevic-Curic and H. I. Maibach (eds.), Percutaneous Penetration Enhancers – Springer, in press. Polymeric micelles in dermal and transdermal delivery. M. Lapteva, M. Möller, Y. N. Kalia. In: N. Dragicevic-Curic and H. I. Maibach (eds.), Percutaneous Penetration Enhancers – Springer, in press. Liquid crystals in dermal and transdermal delivery. M. Lapteva, Y. N. Kalia. In: K. Sugibayashi (eds.), Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds – Springer (Japan), in press. Encapsulation technologies: Polymeric micelles in dermal and transdermal delivery. M. Lapteva, Y. N. Kalia. In: K. Sugibayashi (eds.), Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds – Springer (Japan), in press. Iontophoresis and electroporation. M. Singhal, Y. N. Kalia. In: K. Sugibayashi (eds.), Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds – Springer (Japan), in press.