Pharmaceutical analysis

Fundamentals

Development of new strategies to understand and improve separation techniques of:

  • Selectivity
  • Resolution
  • Throughput
  • Sensitivity
  • Method transfer
  • Automated method development
  • Frictional heating / pressure effects
  • Coupling to sensors

Biopharmaceuticals

Development of methods to analyse monoclonal antibody (mAbs), proteins, fusion proteins, Antibody Drug Conjugates (ADC), etc

  • Chromatographic techniques: SEC, IEX, HIC, RPLC, HILIC
  • Electrophoretic techniques: CZE, CIEF, CGE
  • Coupling with high resolution MS
  • Characterization and quantification of biopharmaceuticals in formulations and in biological matrices

Drugs

Development of methods to analyse drugs, illegal substances, doping agents, secondary metabolites

  • Drug formulation, biological matrices
  • Chromatographic techniques: RPLC, SFC, HILIC, chiral
  • Coupling with MS and MS/MS
  • Characterization and quantification of substances in formulations and biological matrices
 

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